Volumetric analysis of sexually dimorphic limbic nuclei in normal and sex-reversed whiptail lizards

Brain Research

Volumn 838, Issue 1-2, 1999, Pages 104-109

  Wennstrom, Kira L ^a   Blesius, Fae ^a   Crews, David ^a  

^a UNIVERSITY OF TEXAS AT AUSTIN   (United States)

Author keywords

Preoptic area; Reptile; Sex reversed; Ventromedial hypothalamus

Indexed keywords

FADROZOLE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTERIOR HYPOTHALAMUS; ARTICLE; BRAIN SIZE; CONTROLLED STUDY; FEMALE; HYPOTHALAMUS VENTROMEDIAL NUCLEUS; LIZARD; MALE; NONHUMAN; PARTHENOGENESIS; PHENOTYPE; PREOPTIC AREA; PRIORITY JOURNAL; SEX DIFFERENCE; SEX TRANSFORMATION; VIRILIZATION;

ANIMALS; ANTERIOR HYPOTHALAMIC NUCLEUS; AROMATASE INHIBITORS; ENZYME INHIBITORS; FADROZOLE; FEMALE; HYPOTHALAMUS, MIDDLE; LIMBIC SYSTEM; LIZARDS; MALE; PREOPTIC AREA; REFERENCE VALUES; REGRESSION ANALYSIS; SEX CHARACTERISTICS; SEX REVERSAL, GONADAL;

EID: 0033554206     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-8993(99)01702-3     Document Type: Article

References (44)

1. Adkins-Regan E., Watson J. Sexual dimorphism in the avian brain is not limited to the song system of songbirds: a morphometric analysis of the brain of the quail (Coturnix japonica). Brain Res. 514:1990;320-326.
2. Arai Y., Sekine Y., Murakami S. Estrogen and apoptosis in the developing sexually dimorphic preoptic area in female rats. Neurosci. Res. 25:1996;403-407.
3. Arnold A.P. Genetically triggered sexual differentiation of brain and behavior. Horm. Behav. 30:1996;495-505.
4. Baum M.J., Erskine M.S., Kornberg E., Weaver C.E. Prenatal andneonatal testosterone exposure interact to affect differentiation of sexual behavior and partner preference in female ferrets. Behav. Neurosci. 104:1990;183-198.
5. Breedlove S.M. Regional sex differences in steroid accumulation in the nervous system. Trends Neurosci. 6:1983;403-406.
6. Commins D., Yahr P. Adult testosterone levels influence the morphology of a sexually dimorphic area in the mongolian gerbil brain. J. Comp. Neurol. 224:1984;132-140.
7. D. Crews, R. Silver, Reproductive physiology and behavioral interactions in nonmammalian vertebrates, Handbook of Behavioral Neurology, Plenum, New York, 1985, pp. 101-182.
8. Crews D., Wade J., Wilczynski W. Sexually dimorphic areas in the brain of whiptail lizards. Brain Behav. Evol. 36:1990;262-270.
9. Davis E.C., Popper P., Gorski R.A. The role of apoptosis in sexual differentiation of the rat sexually dimorphic nucleus of the preoptic area. Brain Res. 734:1996;10-18.
10. Döhler K.-D., Srivastava S.S., Shryne J.E., Jarzab B., Sipos A., Gorski R.A. Differentiation of the sexually dimorphic nucleus in the preoptic area of the rat brain is inhibited by postnatal treatment with an estrogen antagonist. Neuroendocrinology. 38:1984;297-301.
11. Döhler K.-D., Hines M., Coquelin A., Davis F., Shryne J., Gorski R. Pre- and postnatal influence of diethylstilboestrol on differentiation of the sexually dimorphic nucleus in the preoptic area of the female rat brain. Neuroendocrinol. Lett. 4:1982;361-365.
12. Gahr M., Metzdorf R. The sexually dimorphic expression of androgen receptors in the song nucleus hyperstriatalis ventrale pars caudale of the zebra finch develops independently of gonadal steroids. J. Neurosci. 19:1999;2628-2636.
13. Gorski R.A., Gordon J.H., Shryne J.E., Southam A.M. Evidence for a morphological sex difference within the medial preoptic area of the rat brain. Brain Res. 148:1978;333-346.
14. Grassman M., Crews D. Ovarian and adrenal function in the parthenogenetic whiptail lizard Cnemidophorus uniparens in the field and laboratory. Gen. Comp. Endocrinol. 76:1990;444-450.
15. Gustafson J.E., Crews D. Effect of group size and physiological state of a cagemate on reproduction in the parthenogenetic lizard, Cnemidophorus uniparens (Teiidae). Behav. Ecol. Sociobiol. 8:1981;267-272.
16. Hines M., Davis F., Coquelin A., Goy R., Gorski R. Sexually dimorphic regions in the medial preoptic area and the bed nucleus of the stria terminalis of the guinea pig brain: a description and an investigation of their relationship to gonadal steroids in adulthood. J. Neurosci. 5:1985;40-47.
17. Hoepfner B.A., Ward I.L. Prenatal and neonatal androgen exposure interact to affect sexual differentiation in female rats. Behav. Neurosci. 102:1988;61-65.
18. Houtsmuller E., Brand T., de Jonge F., Joosten R., van de Poll N., Slob A. SDN-POA volume, sexual behavior, and partner preference of male rats affected by perinatal treatment with ATD. Physiol. Behav. 56:1994;535-541.
19. Jacobson C., Csernus V., Shryne J., Gorski R. The influence of gonadectomy, androgen exposure, or a gonadal graft in the neonatal rat on the volume of the sexually dimorphic nucleus of the preoptic area. J. Neurosci. 1:1981;1142-1147.
20. Jacobson C.D., Gorski R.A. Neurogenesis of the sexually dimorphic nucleus of the preoptic area of the rat. J. Comp. Neurol. 196:1981;519-529.
21. Kendrick M., Rand M.S., Crews D. Electrolytic lesions to the ventromedial hypothalamus abolish receptivity in female whiptail lizards, Cnemidophorus uniparens. Brain Res. 680:1995;226-228.
22. Kingston P.A., Crews D. Effects of hypothalamic lesions on courtship and copulatory behavior in sexual and unisexual whiptail lizards. Brain Res. 643:1994;349-351.
23. Matsumoto, Arai Y. Sex difference in volume of the ventromedial nucleus of the hypothalamus in the rat. Endocrinol. Jpn. 30:1983;277-280.
24. Nunez S., Blye R., Thomas P., Reel J., Barnes K., Malley J., Cutler G.J. Recovery of reproductive function in rats treated with the aromatase inhibitor fadrozole. Reprod. Toxicol. 10:1996;373-377.
25. Panzica G., Viglietti-Panzica C., Calcagni M., Anselmetti G., Schumacher M., Balthazart J. Sexual differentiation of and hormonal control of the sexually dimorphic medial preoptic nucleus in the quail. Brain Res. 416:1987;59-68.
26. Pfaff D.W., Schwartz-Giblin S. Cellular mechanisms of female reproductive behaviors. Physiol. Reprod. 2:1988;1487-1568.
27. Reisert C.P. Sexual differentiation of monoaminergic neurons-genetic or epigenetic? Trends Neurosci. 14:1991;468-473.
28. D. Sachs, R.L. Meisel, The physiology of male reproductive behavior, in: E. Knobil, J.D. Neil (Eds.), The Physiology of Reproduction, Raven Press, New York, 1988, pp. 1393-1486.
29. S. Schwartz-Giblin, B.S. McEwen, D.W. Pfaff, Mechanisms of female reproductive behavior, in: R. Brush, S. Levine (Eds.), Psychoendocrinology, Academic Press, New York, 1989, pp. 41-104.
30. Springer M.L., Wade J. The effects of testicular tissue and prehatching inhibition of estrogen synthesis on the development of courtship and copulatory behavior in zebra finches. Horm. Behav. 32:1997;46-59.
31. Thompson R.R., Adkins-Regan E. Ontogeny of a sexually dimorphic nucleus in the preoptic area of the Japanese quail (Coturnix japonica). Dev. Brain Res. 70:1992;231-237.
32. Tobet S., Zahniser D., Baum M. Differentiation in male ferrets of a sexually dimorphic nucleus in the preoptic anterior hypothalamic area requires prenatal estrogen. Neuroendocrinology. 44:1986.
33. Tobet S., Zahniser D., Baum M. Sexual dimorphism in the preoptic/anterior hypothalamic area of ferrets: effects of adult exposure to sex steroids. Brain Res. 364:1986;249-257.
34. Ulibarri, Yahr P. Role of neonatal androgens in sexual differentiation of brain structure, scent marking and gonadotropin secretion in gerbils. Behav. NeuralBiol. 49:1988;27-44.
35. Ulibarri, Yahr P. Effects of androgens and estrogens on sexual differentiation of sex behavior, scent marking, and the sexually dimorphic area of the gerbil hypothalamus. Horm. Behav. 30:1996;107-130.
36. Wade J., Arnold A.P. Functional testicular tissue does not masculinize development of the zebra finch song system. Proc. Natl. Acad. Sci. U.S.A. 93:1996;5264-5268.
37. Wade J., Crews D. The relationship between reproductive state and "sexually" dimorphic brain areas in sexually reproducing and parthenogenetic whiptail lizards. J. Comp. Neurol. 309:1991;507-514.
38. Wade J., Huang J., Crews D. Hormonal control of sex differences in the brain, behavior and accessory sex structures of whiptail lizards (Cnemidophorus species). J. Neuroendocrinol. 5:1993;81-93.
39. Wade J., Springer M.L., Wingfield J.C., Arnold A.P. Neither testicular androgens nor embryonic aromatase activity alters morphology of the neural song system in zebra finches. Biol. Reprod. 55:1996;1126-1132.
40. Weisz J., Ward I.L. Plasma testosterone and progesterone titers of pregnant rats, their male and female fetuses, and neonatal offspring. Endocrinology. 106:1980;306-316.
41. Wennstrom K.L., Crews D. Making males from females: the effects of aromatase inhibitors on a parthenogenetic species of whiptail lizard. Gen. Comp. Endocrinol. 99:1995;316-322.
42. Wibbels T., Crews D. Putative aromatase inhibitor induces male sex determination in a female unisexual lizard and in a turtle with temperature-dependent sex determination. J. Endocrinol. 141:1994;295-299.
43. J.W. Wright, Evolution of the lizards of the genus Cnemidophorus, in: J.W. Wright, L.J. Witt (Eds.), Biology of Whiptail Lizards (Genus Cnemidophorus), Oklahoma Museum of Natural History, Norman, OK, 1993, pp. 27-81.
44. Yahr P. Pars compacta of the sexually dimorphic area of the gerbil hypothalamus: postnatal ages at which development responds to testosterone. Behav. NeuralBiol. 49:1988;118-124.