Simultaneous determination of intermolecular and intramolecular 13C and 2H kinetic isotope effects at natural abundance [5]

Journal of the American Chemical Society

Volumn 121, Issue 40, 1999, Pages 9455-9456

  Singleton, Daniel A ^a   Szymanski, Michael J ^a  

^a TEXAS A AND M UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CARBON 13; DEUTERIUM;

CHEMICAL REACTION; CHEMICAL REACTION KINETICS; CHEMICAL STRUCTURE; LETTER; MOLECULAR INTERACTION; REACTION ANALYSIS;

EID: 0033552247     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja992016z     Document Type: Letter

References (22)

1. An exception occurs when the material of interest is not involved in the rate law, as in some nitrations of aromatics. In such cases, a competition reaction could provide KIEs for a product-determining step after the rate-limiting step.
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22. This methodology has already been applied to palladium-trimethylenemethane cycloadditions: Singleton, D. A.; Schulmeier, B. E. J. Am. Chem. Soc. 1999, 121, 9313-9317.