Functional characterization of structural alterations in the sequence of the vasodilatory peptide maxadilan yields a pituitary adenylate cyclase- activating peptide type 1 receptor-specific antagonist

Journal of Biological Chemistry

Volumn 274, Issue 33, 1999, Pages 23103-23110

  Moro, Osamu ^a,b   Wakita, Kaori ^a   Ohnuma, Manami ^a   Denda, Sumiko ^a   Lerner, Ethan A ^b   Tajima, Masahiro ^a  

^a SHISEIDO RESEARCH CENTER   (Japan)

^b MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HYPOPHYSIS ADENYLATE CYCLASE ACTIVATING POLYPEPTIDE; HYPOPHYSIS ADENYLATE CYCLASE ACTIVATING POLYPEPTIDE RECEPTOR; MAXADILAN;

AMINO ACID SUBSTITUTION; ANIMAL CELL; ARTICLE; CELL STRAIN COS1; CONTROLLED STUDY; DELETION MUTANT; ERYTHEMA; NONHUMAN; PEPTIDE ANALYSIS; PRIORITY JOURNAL; PROTEIN STRUCTURE; RABBIT; SEQUENCE ANALYSIS; SEQUENCE HOMOLOGY;

AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; CIRCULAR DICHROISM; COS CELLS; CYCLIC AMP; CYSTEINE; DNA PRIMERS; INSECT PROTEINS; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; PC12 CELLS; PROTEIN BINDING; PROTEIN CONFORMATION; RABBITS; RATS; RECEPTORS, PITUITARY ADENYLATE CYCLASE-ACTIVATING POLYPEPTIDE; RECEPTORS, PITUITARY ADENYLATE CYCLASE-ACTIVATING POLYPEPTIDE, TYPE I; RECEPTORS, PITUITARY HORMONE; RECOMBINANT PROTEINS; SEQUENCE DELETION; SEQUENCE HOMOLOGY, AMINO ACID; SPECTROPHOTOMETRY, ULTRAVIOLET; VASODILATOR AGENTS;

ANIMALIA; ORYCTOLAGUS CUNICULUS; PHLEBOTOMINAE;

EID: 0033551767     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.274.33.23103     Document Type: Article

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