Synthesis of [1]benzopyrano[4,3-b]pyrrol-4(1H)-ones from N(α)-(2-Oxo-2H-1-benzopyran-4-yl)Weinreb α-aminoamides

Tetrahedron

Volumn 55, Issue 46, 1999, Pages 13211-13224

  Alberola, Angel ^a   Álvaro, Rocío ^a   Ortega, Alfonso González ^a   Sádaba, M Luisa ^a   Sañudo, M Carmen ^a  

^a UNIVERSITY OF VALLADOLID   (Spain)

Author keywords

1 Benzopyrano 4,3 b pyrrole; Knorr pyrrole synthesis; Pyrrolizine; Weinreb amides

Indexed keywords

ALPHA AMINO ACID; BENZOPYRAN DERIVATIVE; COUMARIN DERIVATIVE; KETONE; ORGANOMETALLIC COMPOUND; PROLINE DERIVATIVE; PYRROLE; PYRROLIZINE DERIVATIVE;

ARTICLE; CHEMICAL REACTION; CYCLIZATION; DRUG STRUCTURE; DRUG SYNTHESIS; PRIORITY JOURNAL;

EID: 0033550258     PISSN: 00404020     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0040-4020(99)00802-9     Document Type: Article

References (26)

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19. E.g. approximate relation of commercial prices for alanine derivatives: 2b 19 DM/mol, 6b 843 DM/mol, 8b 7790 DM/mol.
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21. Unpublished additional experiments.
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25. The same procedure was applied for BOP. See ref. 11.
26. 1≠H, are partially cyclized to pyrroles 13 when they are chromatographed on silica gel.