Synthesis of novel cationic lipids with oxyethylene spacers at the linkages between hydrocarbon chains and pseudoglyceryl backbone

Tetrahedron Letters

Volumn 40, Issue 46, 1999, Pages 8167-8171

  Bhattacharya, Santanu ^a   Dileep, P V ^a  

^a INDIAN INSTITUTE OF SCIENCE   (India)

Author keywords

[No Author keywords available]

Indexed keywords

CATION; ETHYLENE DERIVATIVE; GLYCEROL DERIVATIVE; LIPID;

ARTICLE; CROSS LINKING; DRUG SYNTHESIS; LIPOPHILICITY; STRUCTURE ACTIVITY RELATION;

EID: 0033550169     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0040-4039(99)01683-4     Document Type: Article

References (19)

1. For general reviews, see: (a) Miller, A. D. Angew. Chem., Int. Ed. Engl. 1998, 37, 1768. (b) Deshmukh, H. M.: Huang, L. New J. Chem. 1997, 21, 113. (c) Behr, J. P. Acc. Chem. Res. 1993, 26, 274.
2. For general reviews, see: (a) Miller, A. D. Angew. Chem., Int. Ed. Engl. 1998, 37, 1768. (b) Deshmukh, H. M.: Huang, L. New J. Chem. 1997, 21, 113. (c) Behr, J. P. Acc. Chem. Res. 1993, 26, 274.
3. For general reviews, see: (a) Miller, A. D. Angew. Chem., Int. Ed. Engl. 1998, 37, 1768. (b) Deshmukh, H. M.: Huang, L.New J. Chem. 1997, 21, 113. (c) Behr, J. P. Acc. Chem. Res. 1993, 26, 274.
4. (a) Bhattacharya, S.; Mandal, S. S. Biochemistry 1998, 37, 7764.
5. (b) Wheeler, C. J.; Felgner, P. L.; Tsai, Y. J.; Marshall, J.; Sukhu, L.; Doh, S. G.; Hartikka, J.; Nietupski, J.; Manthorpe, M.; Nichols, M.; Plewe, M.; Liang, X.; Norman, J.; Smith, A.; Cheng, S. H. Proc. Natl. Acad. Sci. USA 1996, 93, 114-544.
6. (a) Song, Y. K.; Liu, F.; Chu, S.; Liu, D. Human Gene Therapy 1997, 8, 1585.
7. (b) Felgner, J. H.; Kumar, R.; Sridhar, C. N.; Wheeler, C. J.; Tsai, Y. J.; Border, R.; Ramsey, P.; Martin, M.; Felgner, P. L. J. Biol. Chem. 1994, 269, 2550.
8. (a) Bhattacharya, S.; De, S. J. Org. Chem. 1998, 63, 7640.
9. (b) Bhattacharya, S.; Ghosh, S.; Easwaran, K. R. K. J. Org. Chem. 1998, 63, 9232.
10. (c) Bhattacharya, S.; De, S.; George, S. K. J. Chem. Soc., Chem. Commun. 1997, 2287.
11. (d) Ghosh, S.; Easwaran, K. R. K.; Bhattacharya, S. Tetrahedron Lett. 1996, 37, 5769.
12. (e) Bhattacharya, S.; De, S. J. Chem. Soc., Chem. Commun. 1996, 1283.
13. (f) Bhattacharya, S.; De, S. J. Chem. Soc., Chem. Commun. 1995, 651.
14. Zalipsky, S. Advanced Drug Delivery Reviews 1995, 16, 157.
15. For reviews, see: (a) Woodle, M. C.; Lasic, D. D. Biochim. Biophys. Acta 1992, 1113, 171. (b) Lasic, D. D.; Needham, D.Chem. Rev. 1995, 95, 2601.
16. For reviews, see: (a) Woodle, M. C.; Lasic, D. D. Biochim. Biophys. Acta 1992, 1113, 171. (b) Lasic, D. D.; Needham, D. Chem. Rev. 1995, 95, 2601.
17. Kates, M.; Chan, T. H.; Stanacev, N. Z. Biochemistry 1963, 2, 394.
18. Richard, A. B.; Bornislaw, P. C. J. Org. Chem. 1989, 54, 857.
19. 4N: 671.2. Found: 671.6.