A pilot study of MRI activity before and during interferon beta-1a therapy

Neurology

Volumn 53, Issue 4, 1999, Pages 874-876

  Waubant, E ^a   Goodkin, D E ^a   Sloan, R ^a   Andersson, P B ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Gadolinium enhancing lesions; Interferon beta 1a; MRI

Indexed keywords

BETA1A INTERFERON; GADOLINIUM;

ADULT; ARTICLE; CLINICAL ARTICLE; DRUG MONITORING; FEMALE; HUMAN; IMAGE ANALYSIS; IMAGE ENHANCEMENT; MALE; MULTIPLE SCLEROSIS; NUCLEAR MAGNETIC RESONANCE IMAGING; PRIORITY JOURNAL;

EID: 0033546984     PISSN: 00283878     EISSN: None     Source Type: Journal    
DOI: 10.1212/wnl.53.4.874     Document Type: Article

References (9)

1. Jacobs LD, Cookfair DL, Rudick RA, et al. Intramuscular Interferon beta-1a for disease progression in relapsing multiple sclerosis. Ann Neurol 1996;39:285-294.
2. Simon JH, Jacobs L, Campion M, et al. Magnetic resonance studies of intramuscular interferon β-1a for relapsing multiple sclerosis. Ann Neurol 1998;43:79-87.
3. Li DKB, Zhao G, Hyde R, et al. Comparison of the therapeutic effect of interferon beta-1a (Rebif) on different levels of baseline MRI activity. Neurology 1998;50:A190. Abstract.
4. Paty DW, Zhao G, Hyde R, et al. Comparison between proton density/T2 gadolinium-enhanced T1 MRI in demonstrating a treatment effect and dose difference in PRIMS trial of interferon beta-1a (Rebif). Neurology 1998;50(suppl 4):A190. Abstract.
5. Pozzilli C, Bastianello S, Koudriavtseva T, et al. Magnetic resonance imaging changes with recombinant human interferon-beta-1a: a short term study in relapsing-remitting multiple sclerosis. J Neurol Neurosurg Psychiatry 1996;61:251-258.
6. Poser CM, Paty DW, Scheinberg L, et al. New diagnostic criteria for multiple sclerosis: guidelines for research protocols. Ann Neurol 1983;13:227-231.
7. Goodkin D, Rooney W, Sloan R, et al. A serial study of new multiple sclerosis lesions and white matter from which they arise. Neurology 1998;51:1689-1697.
8. Stone LA, Frank JA, Albert PS, et al. Characterization of MRI response to treatment with interferon beta-1b: contrast-enhancing MRI lesion frequency as a primary outcome. Neurology 1997;49:862-869.
9. Stone LA, Frank JA, Albert PS, et al. The effect of interferon beta on blood-brain barrier disruptions demonstrated by contrast-enhanced magnetic resonance imaging in relapsing-remitting multiple sclerosis. Ann Neurol 1995;37:611-619.