The motif D loop of human immunodeficiency virus type 1 reverse transcriptase is critical for nucleoside 5'-triphosphate selectivity

Journal of Biological Chemistry

Volumn 274, Issue 50, 1999, Pages 35768-35776

  Canard, Bruno ^a   Chowdhury, Kajal ^b   Sarfati, Robert ^c   Doublié, Sylvie ^b,d   Richardson, Charles C ^b  

^a CNRS   (France)

^b HARVARD MEDICAL SCHOOL   (United States)

^c INSTITUT PASTEUR   (France)

^d UNIVERSITY OF VERMONT COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

NUCLEOSIDE TRIPHOSPHATE; RNA DIRECTED DNA POLYMERASE;

ARTICLE; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME SPECIFICITY; ENZYME STRUCTURE; HUMAN IMMUNODEFICIENCY VIRUS 1; NONHUMAN; PRIORITY JOURNAL;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; CLONING, MOLECULAR; CONSERVED SEQUENCE; CRYSTALLOGRAPHY, X-RAY; HIV-1 REVERSE TRANSCRIPTASE; HUMANS; KINETICS; LYSINE; MODELS, MOLECULAR; PROTEIN CONFORMATION; PROTEIN STRUCTURE, QUATERNARY; RECOMBINANT FUSION PROTEINS; RECOMBINANT PROTEINS; RIBONUCLEOTIDES; SEQUENCE ALIGNMENT; SEQUENCE HOMOLOGY, AMINO ACID; SOFTWARE; SUBSTRATE SPECIFICITY; THREONINE;

EID: 0033544856     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.274.50.35768     Document Type: Article

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