Trafficking of liposomal antigen to the trans-Golgi of murine macrophages requires both liposomal lipid and liposomal protein

Experimental Cell Research

Volumn 246, Issue 1, 1999, Pages 203-211

  Rao, Mangala ^a   Rothwell, Stephen W ^a   Wassef, Nabila M ^a   Koolwal, Aditya B ^a   Alving, Carl R ^a  

^a WALTER REED ARMY INSTITUTE OF RESEARCH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

LIPOSOME; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; MEMBRANE PROTEIN;

ANIMAL CELL; ANTIGEN BINDING; ANTIGEN PRESENTING CELL; ARTICLE; CYTOTOXIC T LYMPHOCYTE; GOLGI COMPLEX; MACROPHAGE ACTIVATION; MAJOR HISTOCOMPATIBILITY COMPLEX; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN LIPID INTERACTION; PROTEIN LOCALIZATION;

ANIMALIA; MURINAE;

EID: 0033540275     PISSN: 00144827     EISSN: None     Source Type: Journal    
DOI: 10.1006/excr.1998.4274     Document Type: Article

References (42)

1. Germain R. N., Margoulies D. H. The biochemistry and cell biology of antigen processing and presentation. Annu. Rev. Immunol. 11:1993;403-450.
2. Germain R. N. MHC-dependent antigen processing and peptide presentation: Providing ligands for T lymphocyte activation. Cell. 76:1994;287-299.
3. Wolf P. R., Ploegh H. L. How MHC class II molecules acquire peptide cargo: Biosynthesis and trafficking through the endocytic pathway. Annu. Rev. Cell Biol. 11:1995;267-306.
4. Townsend A. R., Gotch F. M., Davey J. Cytotoxic T cells recognize fragments of the influenza nucleoprotein. Cell. 42:1985;457-467.
5. Braciale T. J., Morrison L. A., Sweetser M. T., Sainbrook J., Gething M. J., Braciale V. L. Antigen presentation pathways to class I and class II MHC-restricted T lymphocytes. Immunol. Rev. 98:1987;95-114.
6. Townsend A., Bodmer H. Antigen recognition by class I-restricted T lymphocytes. Annu. Rev. Immunol. 7:1989;601-624.
7. Rotzschke O., Falk K., Deres K., Schild H., Norda M., Metzger J., Jung G., Rammensee H. G. Isolation and analysis of naturally processed viral peptides as recognized by cytotoxic T cells. Nature. 348:1990;252-254.
8. Moore M. W., Carbone F. R., Bevan M. J. Introduction of soluble protein into the class I pathway of antigen processing and presentation. Cell. 54:1988;777-785.
9. Deres K., Schild H., Wiesmufler K. H., Jung G., Rammensee H. G. In vivo. Nature. 342:1989;561-564.
10. Schild H., Norda M., Deres K., Falk K., Rotzschke O., Wiesmuller K. H., Jung G., Rammensee H. G. Fine specificity of cytotoxic T lymphocytes primedin vivoin vitro. J. Exp. Med. 174:1991;1665-1668.
11. Martinon F., Gras-Masse H., Boutillon C., Chirat F., Deprez B., Guillet J-G., Gomard E., Tartar A., Levy J. P. Immunization of mice with lipopeptides bypasses the prerequisite for adjuvant. Immune response of BALB/c mice to human immunodeficiency virus envelope glycoprotein. J. Immunol. 149:1992;3416-3422.
12. Harding C. V., Song R. Phagocytic processing of exogenous particulate antigens by macrophages for presentation by class I MHC molecules. J. Immunol. 153:1994;4925-4933.
13. Kovacsovics-Bankowski M., Rock K. L. A phagosome-to-cytosol pathway for exogenous antigens presented on MHC class I molecules. Science. 267:1995;243-246.
14. Lopes L. M., Chain B. M. Liposome-mediated delivery stimulates a class I restricted cytotoxic T cell response to soluble antigen. Eur. J. Immunol. 22:1992;287-290.
15. Reddy R., Zhou F., Nair S., Huang L., Rouse B. T. In vivo. J. Immunol. 148:1992;1585-1589.
16. White K., Krzych U., Gordon T. D., Porter M. R., Richards R. L., Alving C. R., Deal C. D., Hollingdale M., Silverman C., Sylvester D. R., Ballou W. R., Gross M. Induction of cytolytic and antibody responses usingPlasmodium falciparum. Vaccine. 11:1993;1341-1346.
17. Alving C. R., Wassef N. M. Cytotoxic T lymphocytes induced by liposomal antigens: Mechanisms of immunological presentation. AIDS Res. and Human Retrovir. 10:1994;S91-S94.
18. Alving C. R., Koulchin V., Glenn G. M., Rao M. Liposomes as carriers of peptide antigens: Induction of antibodies and cytotoxic T lymphocytes to conjugated and unconjugated peptides. Immunol. Rev. 145:1995;5-31.
19. White W. I., Cassatt D. R., Madsen J., Burke S. J., Woods R. M., Wassef N. M., Alving C. R., Koenig S. Antibody and cytotoxic T-lymphocyte responses to a single liposome-associated peptide antigen. Vaccine. 13:1995;1111-1122.
20. Alving C. R. Liposomes as carriers of antigens and adjuvants. J. Immunol. Methods. 140:1991;1-13.
21. Wassef N. M., Alving C. R., Richards R. L. Liposomes as carriers for vaccines. ImmunoMethods. 4:1994;217-222.
22. Fries L. F., Gordon D. M., Richards R. L., Egan J. E., Hollingdale M. R., Gross M., Silverman C., Alving C. R. Liposomal malaria vaccine in humans: A safe and potent adjuvant strategy. Proc. Natl. Acad. Sci. USA. 89:1992;358-362.
23. Heppner D. G., Gordon D. M., Gross M., Wellde B., Leitner W., Krzych U., Schneider I., Wirtz R. A., Richards R. L., Trofa A., Hall T., Sadoff J. C., Boerger P., Alving C. R., Sylvester D. R., Porter T. G., Ballou W. R. Safety, immunogenecity, and efficacy ofPlasmodium falciparum. J. Infect. Dis. 174:1996;361-366.
24. Verma J. N., Wassef N. M., Wirtz R. A., Atkinson C. T., Aikawa M., Loomis L. D., Alving C. R. Phagocytosis of liposomes by macrophages: Intracellular fate of liposomal malaria antigen. Biochim. Biophys. Acta. 1066:1991;229-238.
25. Verma J. N., Rao M., Amselem S., Krzych U., Alving C. R., Green S. J., Wassef N. M. Adjuvant effects of liposomes containing lipid A: Enhancement of liposomal antigen presentation and recruitment of macrophages. Infect. Immun. 60:1992;2438-2444.
26. Rao M., Wassef N. M., Alving C. R., Krzych U. Intracellular processing of liposome-encapsulated antigens by macrophages depends upon the antigen. Infect. Immun. 63:1995;2396-2402.
27. Rao M., Rothwell S. W., Wassef N. M., Pagano R. E., Alving C. R. Visualization of peptides derived from liposome-encapsulated proteins in the trans-Golgi area of macrophages. Immun. Lett. 59:1997;99-105.
28. Alving C. R., Shichijo S., Mattsby-Baltzer I., Richards R. L., Wassef N. M. Preparation and use of liposomes in immunological studies. Liposome Technol. 3:1993;317-343.
29. Titus J. A., Haugland R., Sharrow S. O., Segal D. M. Texas red, a hydrophilic, red-emitting fluorophore for use with fluorescein in dual parameter flow microfluoremetric and fluorescence microscopic studies. J. Immunol. Methods. 50:1982;193-204.
30. Pagano R. E., Sepanski M. A., Martin O. C. Molecular trapping of a fluorescent (NBD) ceramide analog at the Golgi apparatus of fixed cells: Interaction with endogenous lipids provides a trans-Golgi marker for both light and electron microscopy. J. Cell Biol. 109:1989;2067-2079.
31. Segal A. W., Willis E. J., Richmond J. E., Slavin G., Black C. D. V., Gregoriadis G. Morphological observations on the cellular and subcellular destination of intravenously administered liposomes. Br. J. Exp. Pathol. 55:1974;320-327.
32. Gregoriadis G., Buckland R. A. Enzyme-containing liposomes alleviate a model for storage disease. Nature. 244:1973;170-172.
33. Straubinger R. M., Hong K., Friend D. S., Papahadjopoulos D. Endocytosis of liposomes and intracellular fate of encapsulated molecules: Encounter with a low pH compartment after internalization in coated vesicles. Cell. 32:1983;1069-1079.
34. Dijkstra J., van Galen M., Regts D., Scherphof G. Uptake and processing of liposomal phospholipids by Kupffer cellsin vitro. Eur. J. Biochem. 148:1985;391-397.
35. Connor J., Huang L. Efficient cytoplasmic delivery of a fluorescent dye by pH-sensitive immunoliposomes. J. Cell Biol. 101:1985;582-589.
36. Zhou F., Watkins S. C., Huang L. Characterization and kinetics of MHC class I-restricted presentation of a soluble antigen delivered by liposomes. Immunobiology. 190:1994;35-52.
37. Perry D. G., Martin W. J. II. Fluorescent liposomes as quantitative markers of phagocytosis by alveolar macrophages. J. Immunol. Methods. 181:1995;269-285.
38. Kagiwada S., Murata M., Hishida S., Tagaya M., Yamashina S., Ohnishi S-I. In vitro. J. Biol. Chem. 268:1993;1430-1435.
39. Kobayashi T., Pagano R. E. ATP-dependent fusion of liposomes with Golgi apparatus of perforated cells. Cell. 55:1988;797-805.
40. +. Nature. 372:1994;691-694.
41. --. Nature. 360:1997;593-597.
42. Prigozy T. I., Sieling P. A., Clemens D., Stewart P. L., Behar S. M., Porcelli S. A., Brenner M. B., Modlin R. L., Kronenberg M. M. The mannose receptor delivers lipoglycan antigens to endosomes for presentation to T cells by CD1b molecules. Immunity. 6:1997;187-197.