The oral vitamin E tolerance test - An attempt at standardisation;Der orale vitamin-E-belastungstest - Versuch einer standardisierung

Wiener Klinische Wochenschrift

Volumn 111, Issue 13, 1999, Pages 517-522

  Jost, Wolfgang H ^a   Voran, Anette ^b   Trabert, Wolfgang ^c   König, Jochen ^b   Schimrigk, Klaus ^b  

^a DEUTSCHE KLINIK FÜR DIAGNOSTIK   (Germany)

^b SAARLAND UNIVERSITY   (Germany)

^c Department of Surgery   (Germany)

Author keywords

Tocopherol; Normal values; Tolerance test

Indexed keywords

ALPHA TOCOPHEROL; CHOLESTEROL; TRIACYLGLYCEROL;

ADULT; AGED; ALPHA TOCOPHEROL DEFICIENCY; AREFLEXIA; ARTICLE; CEREBELLAR ATAXIA; DRUG ELIMINATION; DRUG TOLERANCE; FEMALE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN EXPERIMENT; HYPESTHESIA; MALABSORPTION; MALE; MILK; MUSCLE WEAKNESS; NORMAL HUMAN; NYSTAGMUS; ORAL DRUG ADMINISTRATION; RETINOPATHY; VITAMIN METABOLISM;

ADMINISTRATION, ORAL; ADOLESCENT; ADULT; AGED; DRUG TOLERANCE; FEMALE; HUMANS; MALE; MIDDLE AGED; REFERENCE STANDARDS; VITAMIN E; VITAMIN E DEFICIENCY;

EID: 0033538581     PISSN: 00435325     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (35)

1. Amiel J, Maziere JC, Beugler I, König M, Reutenauer L, Loux N, Bonnefont D, Feo C, Landrieu P (1995) Familial isolated vitamin E deficiency. Extensive study of a large family with a 5-year therapeutic follow-up. J Inder Metab Dis 18: 333-340
2. Arita M, Sato Y, Miyata A, et al (1995) Human α-tocopherol transfer protein: cDNA cloning, expression and chromosomal localization. Biochem J 306: 437-443
3. Ben Hamida C, Dörflinger N, Belal S, Lindner C, Reutenauer L, Dib C, Gyapay G, Vignal A, Le Paslier D, Cohen D, Pandolfo M, Mokini V, Novelli G, Hentati F, Ben Hamida M, MandelL JL, König M (1993) Localization of Friedreich ataxia phenotype with selective vitamin E deficiency to chromosome 8q by homozygosity mapping. Nature Genet 5: 195-200
4. Brin MF (1985) Blind loop syndrome, vitamin E malabsorption, and spinocerebellar degeneration. Neurology 35: 338-342
5. Böhles H (1988) Resorptionsdynamik unterschiedlicher Vitamin-E-Mengen bei gesunden jungen Männern. Vita Min Spur 3: 134-136
6. Dörflinger N, Linder C, Ouahchi K, Gyapay G, Weissenbach J, Lepaslier D, Rigault P, Belal S, Ben Ha-Mida C, Hentati F, et alL (1995) Ataxia with vitamin E deficiency: refinement of genetic localization and analysis of linkage di-equilibrium by using new markers in 14 families. Am J Hum Genet 56: 1116-1124
7. Farrell PM, Levine SL, Murphy D, Adams AJ (1978) Plasma tocopherol levels and tocopherol-lipid relationships in a normal population of children al compared to healthy adults. Am J Clin Nutr 31: 1720-1726
8. Guggenheim MA, Jackson V, Lilly J, Silverman A (1983) Vitamin E deficiency and neurologic disease in children with chronic cholestasis: A prospective study. J Pediat 102: 577-579
9. Guggenheim MA, Ringel SP, Silverman A, Grabert BE, Neville HE (1982) Progressiv neuromuscular disease in children with chronic cholestasis and vitamin E deficiency: clinical and muscle biopsy findings and treatment with a-tocopherol. Ann NY Acad Sci 393: 84-93
10. Hartung J (1985) Lehr- und Handbuch der angewandten Statistik. 3. Aufl. R. Oldenbourg-Verlag, München-Wien, S 239
11. Hentati A, Deng HX, Hung WY, Nayer M, Ahmed MS, He X, Tim R, Stumpf DA, Siddique T (1996) Human α-tocopherol transfer protein: Gene structure and mutations in familial vitamin E deficiency. Ann Neurol 39: 295-300
12. Horwitt MK, Harvey CC, Dahm CH, Searcy MT (1972) Relationship between tocopherol and serum lipid levels for determnation of nutritional adequacy. Ann NY Acad Sci 203: 223-236
13. Kasparek S (1980) Chemistry of tocopherols and tocotrienols. In: Machlin LJ (ed) Vitamin A-E. Comprehensiv Treatise. Marcel Dekker, New York, pp 7-65
14. Macmahon MT, Neale G (1970) The absorption of α-tocopherol in control subjects and in patients with intestinal malabsorption. Clin Sci 38: 197-210
15. McWhirter WR (1975) Plasma tocopherol levels in infants and children. Acta Pediat Scand 64: 446-448
16. Muller DPR, Harries JT, Lloyd JK (1974) The relative importance of the factors involved in the absorption of vitamin E in children. Gut 15: 966-971
17. Muller DPR, Lloyd JK (1982) Effect of large oral doses of vitamin E on the neurological sequelae of patients with abetalipoproteinemia. Ann NY Acad Sci 393: 133-142
18. Ouahchi K, Arita M, Kayden H, Hentati F, Ben-Hamida M, Sokol R, Arai H, Inoue K, Mandel JL, Koenig M (1995) Ataxia with isolated vitamin E deficiency is caused by mutations in the alpha-tocopherol transfer protein. Nat Genet 9: 141-145
19. Papas AM (1993) Vitamin E and exercise: aspects of biokinetics. World Rev Nutr Diet 72: 165-176
20. Rubinstein HM, Dietz AA, Srinavasan R (1969) Relation of vitamin E and serum lipids. Clin Chim Acta 23: 1-6
21. Skopnik H, Karl M, Kusenbach G, Bergt U, Geron M, Heimann G (1990) Einfluss des Ernährungsstatus auf die Absorptionskinetik von Vitamin E bei Mukoviszidose (CF). Klin Pädiatr 202: 43-49
22. Sokol RJ, Heubi JE, Iannaccone ST, Bove KE, Balisteri WF (1984) Vitamin E deficiency with normal serum -vitamin E concentrations in children with chronic cholestasis. N Engl J Med 310: 1209-1212
23. Sokol RJ, Kayden HJ, Bettis DB, Traber MG, Neville H, Ringel S, Wilson WB, Stumpf DA (1988) Isolated vitamin E deficiency in the absence of fat malabsorption - familial and sporadic cases: Charakterisation and investigation of causes. J Lab Clin Med 111: 548-559
24. Sokol RJ, Reardon MC, Accurso FJ, Stall C, Narkewicz M, Abman SH, Hammond KB (1989) Fat-soluble-vitamin status during the first year of life in infants with cystic fibrosis identified by screening of newborns. Am J Clin Nutr 20: 1064-1071
25. Sokol RJ (1990) Vitamin E and neurologic deficits. Adv Pediatr 37: 119-139
26. Traber MG, Olivecrona T, Kayden HJ (1985) Bovine milk lipo-protein lipase transfers tocopherol to human fibroblasts during triglyceride hydrolysis in vitro. J Clin Invest 75: 1729-1734
27. Traber MG, Goldberg I, Davidson E, et al (1990) Vitamin E uptake by human intestinal cells during lipolysis in vitro. Gastroenterology 98: 96-103
28. Traber MG, Rudel LL, Burton GW, Hughes L, Ingold KU, Kayden HJ (1990) Nascent VLDL from liver perfusions of cynomolgus monkeys are preferentially enriched in RRR-compared with SRR-α-tocopherol: studies using deuterated tocopherols. J Lipid Res 31: 687-694
29. Traber MG, Burton GW, Hughes L, Ingold KU, Hidaka H, Malloy M, Kane J, Hyams J, Kayden HJ (1992) Discrimination between forms of vitamin E by humans with and without genetic abnormalities of lipoprotein metabolism. J Lipid Res 33: 1171-1182
30. Traber MG, Ramakrishnan R, Kayden HJ (1994) Human plasma vitamin E kinetics demonstrate rapid recycling of plasma RRR-α-tocopherol. Proc Natl Acad Sci USA 91: 10005-10008
31. Trabert W, Stober T, Mielke U, Siu Heck F, Schimrigk K (1989) Isolierter Vitamin-E-Mangel. Fortschr Neurol Psychiat 57: 495-501
32. Turnham DI, Smith E, Flora PS (1988) Concurrent liquid-chromatographic assay of retinol, α-tocopherol, β-carotene, α-carotene, lycopene, and β-cryptoxanthin in plasma, with tocopherol acetate as internal standard. Clin Chem 34: 377-381
33. Vatassery GT, Morley JF, Kuskowski MA (1983) Vitamin E in plasma and platelets of human diabetic patients and control subjects. Am J Clin Nutr 37: 641-644
34. Yokota T, Yoshiaki W, Furukawa T, Tsukagoshi H, Uchihara T, Watabiki S (1987) Adult-onset spinocerebellar syndrome with idiopathic vitamin E deficiency. Ann Neurol 22: 84-87
35. Winkelhofer-Roob B, Tuchschmid PE, Molinari L, Shmerling DH (1996) Response to a single oral dose of all-rac-α-tocopheryl acetate in patients with cystic fibrosis and in healthy individuals. Am Clin Nutr 63: 717-721