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Volumn 17, Issue 15-16, 1999, Pages 1951-1963

Vaccine potential of a herpes simplex virus type 2 mutant deleted in the PK domain of the large subunit of ribonucleotide reductase (ICP10)

Author keywords

[No Author keywords available]

Indexed keywords

HERPES SIMPLEX VACCINE;

EID: 0033537972     PISSN: 0264410X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0264-410X(98)00470-8     Document Type: Article
Times cited : (43)

References (45)
  • 2
    • 0005915665 scopus 로고
    • The role of immunosuppression in herpes simplex virus pathogenesis and its relationship to AIDS
    • In: Aurelian, L., editor Boston, MA: Kluwer Academic Publishers
    • Aurelian L. The role of immunosuppression in herpes simplex virus pathogenesis and its relationship to AIDS. In: Aurelian, L., editor. Herpesviruses, the immune system and AIDS. Boston, MA: Kluwer Academic Publishers, 1990. p. 139-69.
    • (1990) Herpesviruses, the Immune System and AIDS , pp. 139-169
    • Aurelian, L.1
  • 3
    • 0024382163 scopus 로고
    • Identification of immediate-early type cis-response elements in the promoter for the ribonucleotide reductase large subunit from herpes simplex virus type 2
    • Wymer J.P., Chung T.D., Chang Y.N., Hayward G.S., Aurelian L. Identification of immediate-early type cis-response elements in the promoter for the ribonucleotide reductase large subunit from herpes simplex virus type 2. J. Virol. 63:1989;2773-2784.
    • (1989) J. Virol. , vol.63 , pp. 2773-2784
    • Wymer, J.P.1    Chung, T.D.2    Chang, Y.N.3    Hayward, G.S.4    Aurelian, L.5
  • 4
    • 0027248672 scopus 로고
    • The RR1 gene of herpes simplex virus type 1 is uniquely trans-activated by ICP0 during infection
    • Desai P., Ramakrishnan R., Lin Z.W., Osak B., Glorioso J.C., Levine M. The RR1 gene of herpes simplex virus type 1 is uniquely trans-activated by ICP0 during infection. J. Virol. 67:1993;6125-6135.
    • (1993) J. Virol. , vol.67 , pp. 6125-6135
    • Desai, P.1    Ramakrishnan, R.2    Lin, Z.W.3    Osak, B.4    Glorioso, J.C.5    Levine, M.6
  • 5
    • 0030916046 scopus 로고    scopus 로고
    • AP-1 cis-response elements are involved in basal expression and Vmw110 transactivation of the large subunit of herpes simplex virus type 2 ribonucleotide reductase (ICP0)
    • Zhu J., Aurelian L. AP-1 cis-response elements are involved in basal expression and Vmw110 transactivation of the large subunit of herpes simplex virus type 2 ribonucleotide reductase (ICP0). Virology. 231:1997;301-312.
    • (1997) Virology , vol.231 , pp. 301-312
    • Zhu, J.1    Aurelian, L.2
  • 6
    • 0025861672 scopus 로고
    • Induction ofcellular transcription factors in trigeminal ganglia of mice by corneal scarification, herpes simplex virus type 1 infection, and explanation of trigeminal ganglia
    • Valyi-Nagy T., Deshmane S., Dillner A., Fraser N.W. Induction ofcellular transcription factors in trigeminal ganglia of mice by corneal scarification, herpes simplex virus type 1 infection, and explanation of trigeminal ganglia. J. Virol. 65:1991;4142-4152.
    • (1991) J. Virol. , vol.65 , pp. 4142-4152
    • Valyi-Nagy, T.1    Deshmane, S.2    Dillner, A.3    Fraser, N.W.4
  • 7
    • 0030923356 scopus 로고    scopus 로고
    • Gene expression during reactivation of herpes simplex virus type 1 from latency in the peripheral nervous system is different from that during lytic infection of tissue cultures
    • Tal-Singer R., Lasner T.M., Podrzucki W., Skokotas A., Laeary J.J., Berger S.L., Fraser N.W. Gene expression during reactivation of herpes simplex virus type 1 from latency in the peripheral nervous system is different from that during lytic infection of tissue cultures. J. Virol. 71:1997;5268-5276.
    • (1997) J. Virol. , vol.71 , pp. 5268-5276
    • Tal-Singer, R.1    Lasner, T.M.2    Podrzucki, W.3    Skokotas, A.4    Laeary, J.J.5    Berger, S.L.6    Fraser, N.W.7
  • 8
    • 0001042479 scopus 로고    scopus 로고
    • Herpes simplex virus type 2: unique biological properties include neoplastic potential mediated by the PK domain of the large subunit of ribonucleotide reductase
    • PubMed No: 9459654 URL
    • Aurelian L. Herpes simplex virus type 2: unique biological properties include neoplastic potential mediated by the PK domain of the large subunit of ribonucleotide reductase. In: Frontiers in Bioscience, 3, d237-249, PubMed No: 9459654, 1998. URL:http://bioscience.org/1998/v3/ d/aurelian/list.htm.
    • (1998) In: Frontiers in Bioscience , vol.3
    • Aurelian, L.1
  • 9
    • 0023880185 scopus 로고
    • Herpes simplex virus type 1-induced ribonucleotide reductase activity is dispensable for virus growth and DNA synthesis:isolation and characterization of an ICP6lacZ insertion mutant
    • Goldstein D.J., Weller S.K. Herpes simplex virus type 1-induced ribonucleotide reductase activity is dispensable for virus growth and DNA synthesis:isolation and characterization of an ICP6lacZ insertion mutant. J. Virol. 62:1988;196-205.
    • (1988) J. Virol. , vol.62 , pp. 196-205
    • Goldstein, D.J.1    Weller, S.K.2
  • 10
    • 0026500493 scopus 로고
    • Deletion of herpes simplex virus type 1 ribonucleotide reductase gene alters virulence and latency in vitro
    • Idowu A.D., Fraser-Smith E.B., Paffenberger K.L., Herman R.C. Deletion of herpes simplex virus type 1 ribonucleotide reductase gene alters virulence and latency in vitro. Antiviral Res. 17:1992;145-156.
    • (1992) Antiviral Res. , vol.17 , pp. 145-156
    • Idowu, A.D.1    Fraser-Smith, E.B.2    Paffenberger, K.L.3    Herman, R.C.4
  • 11
    • 0024464324 scopus 로고
    • A herpes simplex virus ribonucleotide reductase deletion mutant is defective for productive acute and reactivatable latent infections of mice and for replication in mouse cells
    • Jacobson J.G., Leib D.A., Goldstein D.J., Bogard C.L., Schaffer P.A., Weller S.K., Coen D.M. A herpes simplex virus ribonucleotide reductase deletion mutant is defective for productive acute and reactivatable latent infections of mice and for replication in mouse cells. Virology. 173:1989;276-283.
    • (1989) Virology , vol.173 , pp. 276-283
    • Jacobson, J.G.1    Leib, D.A.2    Goldstein, D.J.3    Bogard, C.L.4    Schaffer, P.A.5    Weller, S.K.6    Coen, D.M.7
  • 12
    • 0024335047 scopus 로고
    • Protein kinase activity associated with the large subunit of the herpes simplex virus type ribonucleotide reductase (ICP10)
    • Chung T.D., Wymer J.P., Smith C.C., Kulka M., Aurelian L. Protein kinase activity associated with the large subunit of the herpes simplex virus type ribonucleotide reductase (ICP10). J. Virol. 63:1989;3389-3398.
    • (1989) J. Virol. , vol.63 , pp. 3389-3398
    • Chung, T.D.1    Wymer, J.P.2    Smith, C.C.3    Kulka, M.4    Aurelian, L.5
  • 13
    • 0030035137 scopus 로고    scopus 로고
    • ATP and SH3 binding sites in the protein kinase of the large subunit of herpes simplex virus type 2 of ribonucleotide reductase (ICP10)
    • Nelson J.W., Zhu J., Smith C.C., Kulka M., Aurelian L. ATP and SH3 binding sites in the protein kinase of the large subunit of herpes simplex virus type 2 of ribonucleotide reductase (ICP10). J. Biol. Chem. 271:1996;17021-17027.
    • (1996) J. Biol. Chem. , vol.271 , pp. 17021-17027
    • Nelson, J.W.1    Zhu, J.2    Smith, C.C.3    Kulka, M.4    Aurelian, L.5
  • 14
    • 0029866493 scopus 로고    scopus 로고
    • The novel protein kinase of the RR1 subunit of herpes simplex virus has autophosphorylation and transphosphorylation activity that differs in its ATP requirements for HSV-1 and HSV-2
    • Peng T., Hunter J.R.C., Nelson J.W. The novel protein kinase of the RR1 subunit of herpes simplex virus has autophosphorylation and transphosphorylation activity that differs in its ATP requirements for HSV-1 and HSV-2. Virology. 216:1996;184-196.
    • (1996) Virology , vol.216 , pp. 184-196
    • Peng, T.1    Hunter, J.R.C.2    Nelson, J.W.3
  • 15
    • 0029017846 scopus 로고
    • Characterization of the novel protein kinase activity present in the R1 subunit of herpes simplex virus ribonucleotide reductase
    • Cooper J., Conner J., Clements J.B. Characterization of the novel protein kinase activity present in the R1 subunit of herpes simplex virus ribonucleotide reductase. J.Virol. 69:1995;4979-4985.
    • (1995) J.Virol. , vol.69 , pp. 4979-4985
    • Cooper, J.1    Conner, J.2    Clements, J.B.3
  • 16
    • 0025851215 scopus 로고
    • Genomic sequences homologous to the protein kinase region of the bifunctional herpes simplex virus type 2 protein ICP10
    • Smith C.C., Wymer J.P., Luo J.H., Aurelian L. Genomic sequences homologous to the protein kinase region of the bifunctional herpes simplex virus type 2 protein ICP10. Virus Genes. 5(3):1991;215-226.
    • (1991) Virus Genes , vol.5 , Issue.3 , pp. 215-226
    • Smith, C.C.1    Wymer, J.P.2    Luo, J.H.3    Aurelian, L.4
  • 17
    • 0346596212 scopus 로고
    • Multistep transformation by defined fragments of herpes simplex virus type 2 DNA: Oncogenic region and its gene product
    • Hayashi Y., Iwasaka T., Smith C.C., Aurelian L., Lewis G.K., Ts'o P.O.P. Multistep transformation by defined fragments of herpes simplex virus type 2 DNA: Oncogenic region and its gene product. Proc. Natl. Acad. Sci. 82:1985;8493-8497.
    • (1985) Proc. Natl. Acad. Sci. , vol.82 , pp. 8493-8497
    • Hayashi, Y.1    Iwasaka, T.2    Smith, C.C.3    Aurelian, L.4    Lewis, G.K.5    Ts'O, P.O.P.6
  • 18
    • 0028220357 scopus 로고
    • The transmembrane domain of the large subunit of HSV-2 ribonucleotide reductase (ICP10) is required for the transformation-related signaling pathways that involve ras activation
    • Smith C.C., Luo J.H., Hunter J.C.R., Ordonez J.V., Aurelian L. The transmembrane domain of the large subunit of HSV-2 ribonucleotide reductase (ICP10) is required for the transformation-related signaling pathways that involve ras activation. Virology. 200:1994;598-612.
    • (1994) Virology , vol.200 , pp. 598-612
    • Smith, C.C.1    Luo, J.H.2    Hunter, J.C.R.3    Ordonez, J.V.4    Aurelian, L.5
  • 19
    • 0031684594 scopus 로고    scopus 로고
    • The PK domain of the large subunit of herpes simplex virus type 2 ribonucleotide reductase (ICP10) is involved in IE gene transcription and virus growth
    • Smith C.C., Peng T., Kulka M., Aurelian L. The PK domain of the large subunit of herpes simplex virus type 2 ribonucleotide reductase (ICP10) is involved in IE gene transcription and virus growth. J. Virol. 1998;72:9131-41.
    • (1998) J. Virol. , vol.72 , pp. 9131-9141
    • Smith, C.C.1    Peng, T.2    Kulka, M.3    Aurelian, L.4
  • 20
    • 0001829730 scopus 로고
    • Amino-terminal epitope of herpes simplex virus type 2 ICP10 protein as a molecular diagnostic marker for cervical intraepithelial neoplasia
    • Aurelian L., Terzano P., Smith C.C., Chung T.D., Shamsuddin A., Costa S., Orlandi C. Amino-terminal epitope of herpes simplex virus type 2 ICP10 protein as a molecular diagnostic marker for cervical intraepithelial neoplasia. Cancer Cells. 7:1989;187-191.
    • (1989) Cancer Cells , vol.7 , pp. 187-191
    • Aurelian, L.1    Terzano, P.2    Smith, C.C.3    Chung, T.D.4    Shamsuddin, A.5    Costa, S.6    Orlandi, C.7
  • 21
    • 0019869533 scopus 로고
    • Enhancement of focus formation in neoplastic transformation by early herpes simplex virus type 2 functions
    • Manak M.M., Aurelian L., Ts'o P.O.P. Enhancement of focus formation in neoplastic transformation by early herpes simplex virus type 2 functions. J. Virol. 40:1981;289-300.
    • (1981) J. Virol. , vol.40 , pp. 289-300
    • Manak, M.M.1    Aurelian, L.2    Ts'O, P.O.P.3
  • 22
    • 0026696657 scopus 로고
    • Expression of the large subunit of herpes simplex virus type 2 ribonucleotide reductase (ICP10) is required for virus growth and neoplastic transformation
    • Smith C.C., Kulka M., Wymer J.P., Chung T.D., Aurelian L. Expression of the large subunit of herpes simplex virus type 2 ribonucleotide reductase (ICP10) is required for virus growth and neoplastic transformation. J. Gen. Virol. 73:1992;1417-1428.
    • (1992) J. Gen. Virol. , vol.73 , pp. 1417-1428
    • Smith, C.C.1    Kulka, M.2    Wymer, J.P.3    Chung, T.D.4    Aurelian, L.5
  • 23
    • 0026554161 scopus 로고
    • Protection from herpes simplex virus type 2 is associated with T-cells involved in delayed type hypersensitivity that recognize glycosylation-related epitopes on glycoprotein D
    • Wachsman M., Luo J.H., Aurelian L., Paoletti E. Protection from herpes simplex virus type 2 is associated with T-cells involved in delayed type hypersensitivity that recognize glycosylation-related epitopes on glycoprotein D. Vaccine. 10:1992;447-454.
    • (1992) Vaccine , vol.10 , pp. 447-454
    • Wachsman, M.1    Luo, J.H.2    Aurelian, L.3    Paoletti, E.4
  • 24
    • 0024066709 scopus 로고
    • Expression of herpes simplex virus glycoprotein D on antigen presenting cells infected with vaccinia recombinants and protective immunity
    • Wachsman M., Aurelian L., Hunter J.C.R., Perkus M.E., Paoletti E. Expression of herpes simplex virus glycoprotein D on antigen presenting cells infected with vaccinia recombinants and protective immunity. Biosci. Rep. 8:1988;323-334.
    • (1988) Biosci. Rep. , vol.8 , pp. 323-334
    • Wachsman, M.1    Aurelian, L.2    Hunter, J.C.R.3    Perkus, M.E.4    Paoletti, E.5
  • 25
    • 0003846613 scopus 로고
    • Herpes simplex viruses
    • In: Specter S., Lancz G., editors NY: Elsevier Science Pub.
    • Aurelian L. Herpes simplex viruses. In: Specter S., Lancz G., editors. Clinical virology manual. 2nd ed. NY: Elsevier Science Pub., 1992. p. 473-94.
    • (1992) Clinical Virology Manual. 2nd Ed. , pp. 473-494
    • Aurelian, L.1
  • 26
    • 0018877117 scopus 로고
    • Herpes simplex virus phosphoproteins. I. Phosphate cycles on and off some viral polypeptides and can alter their affinity for DNA
    • Wilcox K.W., Kohn A., Sklyanskaya E., Roizman B. Herpes simplex virus phosphoproteins. I. Phosphate cycles on and off some viral polypeptides and can alter their affinity for DNA. J. Virol. 33:1980;167-182.
    • (1980) J. Virol. , vol.33 , pp. 167-182
    • Wilcox, K.W.1    Kohn, A.2    Sklyanskaya, E.3    Roizman, B.4
  • 27
    • 0027420465 scopus 로고
    • Isolation of herpes simplex virus type 1 mutant with a deletion in the virion host shutoff gene and identification of multiple forms of the vhs (UL41) polypeptide
    • Read G.S., Karr B.M., Knight K. Isolation of herpes simplex virus type 1 mutant with a deletion in the virion host shutoff gene and identification of multiple forms of the vhs (UL41) polypeptide. J. Virol. 67:1993;7149-7160.
    • (1993) J. Virol. , vol.67 , pp. 7149-7160
    • Read, G.S.1    Karr, B.M.2    Knight, K.3
  • 28
    • 0023258588 scopus 로고
    • Immunization of experimental animals with reconstituted glycoprotein mixtures of herpes simplex virus 1 and 2: Protection against challenge with virulent virus
    • Meignier B., Jourdier T.M., Norrild B., Pereira L., Roizman B. Immunization of experimental animals with reconstituted glycoprotein mixtures of herpes simplex virus 1 and 2: protection against challenge with virulent virus. J. Inf. Dis. 155:1987;921-930.
    • (1987) J. Inf. Dis , vol.155 , pp. 921-930
    • Meignier, B.1    Jourdier, T.M.2    Norrild, B.3    Pereira, L.4    Roizman, B.5
  • 29
    • 0012637140 scopus 로고
    • Current developments in herpes simplex virus vaccines
    • Burke R.L. Current developments in herpes simplex virus vaccines. Semin. Virol. 4:1993;187-197.
    • (1993) Semin. Virol. , vol.4 , pp. 187-197
    • Burke, R.L.1
  • 30
    • 0023845903 scopus 로고
    • Virulence and establishment of latency by genetically engineered deletion mutants of herpes simplex virus 1
    • Meignier B., Longnecker R., Mavroma-Nazos P., Sears A.E., Roizman B. Virulence and establishment of latency by genetically engineered deletion mutants of herpes simplex virus 1. Virology. 162:1988;251-254.
    • (1988) Virology , vol.162 , pp. 251-254
    • Meignier, B.1    Longnecker, R.2    Mavroma-Nazos, P.3    Sears, A.E.4    Roizman, B.5
  • 31
    • 0021192133 scopus 로고
    • Immunity in the female genital tract after intravaginal vaccination of mice with an attenuated strain of herpes simplex virus type 2
    • McDermott M.R., Smiley J.R., Leslie P., Brais J., Rudzroga H.E., Bienenstock J. Immunity in the female genital tract after intravaginal vaccination of mice with an attenuated strain of herpes simplex virus type 2. J. Virol. 51:1984;747-773.
    • (1984) J. Virol. , vol.51 , pp. 747-773
    • McDermott, M.R.1    Smiley, J.R.2    Leslie, P.3    Brais, J.4    Rudzroga, H.E.5    Bienenstock, J.6
  • 32
    • 0025837081 scopus 로고
    • Immune responses to herpes simplex virus in guinea pigs (footpad model) and mice immunized with vaccinia virus recombinants containing herpes simplex virus glycoprotein D
    • (review)
    • Aurelian L., Smith C.C., Wachsman M., Paoletti E. Immune responses to herpes simplex virus in guinea pigs (footpad model) and mice immunized with vaccinia virus recombinants containing herpes simplex virus glycoprotein D. Rev. Infect. Dis. 13 (Suppl 11):1991;924-934. (review).
    • (1991) Rev. Infect. Dis. , vol.1311 , pp. 924-934
    • Aurelian, L.1    Smith, C.C.2    Wachsman, M.3    Paoletti, E.4
  • 33
    • 0032526336 scopus 로고    scopus 로고
    • T-lymphocytes are required for protection of the vaginal mucosae and sensory ganglia of immune mice against reinfection with herpes simplex virus type 2
    • Milligan G.N., Bernstein D.I., Bourne N. T-lymphocytes are required for protection of the vaginal mucosae and sensory ganglia of immune mice against reinfection with herpes simplex virus type 2. J. Immunol. 160:1998;6093-6100.
    • (1998) J. Immunol. , vol.160 , pp. 6093-6100
    • Milligan, G.N.1    Bernstein, D.I.2    Bourne, N.3
  • 34
    • 0028845067 scopus 로고
    • Vaccination of mice with herpes simplex virus type 1 glycoprotein D DNA produces low levels of protection against lethal HSV-1 challenge
    • Ghiasi H., Cia S., Slanina S., Nesburn A.B., Wechsler S.L. Vaccination of mice with herpes simplex virus type 1 glycoprotein D DNA produces low levels of protection against lethal HSV-1 challenge. Antiviral Res. 28:1995;147-157.
    • (1995) Antiviral Res. , vol.28 , pp. 147-157
    • Ghiasi, H.1    Cia, S.2    Slanina, S.3    Nesburn, A.B.4    Wechsler, S.L.5
  • 35
    • 0030917882 scopus 로고    scopus 로고
    • Construction and characterization of a replication-defective Herpes simplex virus 2 ICP8 mutant strain and its use in immunization studies in a guinea pig model of genital disease
    • Da Costa X.J., Bourne N., Stanberry L.R., Knipe D.M. Construction and characterization of a replication-defective Herpes simplex virus 2 ICP8 mutant strain and its use in immunization studies in a guinea pig model of genital disease. Virology. 232:1997;1-12.
    • (1997) Virology , vol.232 , pp. 1-12
    • Da Costa, X.J.1    Bourne, N.2    Stanberry, L.R.3    Knipe, D.M.4
  • 36
    • 0031948661 scopus 로고    scopus 로고
    • Evaluation of a live attenuated recombinant virus RAV 9395 as a herpes simplex virus type 2 vaccine in guinea pigs
    • Spector F.C., Kern E.R., Palmer J., Kaiwar R., Cha T.-A., Brown P., Spaete R.R. Evaluation of a live attenuated recombinant virus RAV 9395 as a herpes simplex virus type 2 vaccine in guinea pigs. J. Inf. Dis. 177:1998;1143-1154.
    • (1998) J. Inf. Dis. , vol.177 , pp. 1143-1154
    • Spector, F.C.1    Kern, E.R.2    Palmer, J.3    Kaiwar, R.4    Cha, T.-A.5    Brown, P.6    Spaete, R.R.7
  • 37
    • 0028020595 scopus 로고
    • Protective vaccination against primary and recurrent disease caused by herpes simplex virus (HSV) type 2 using a genetically disabled HSV-1
    • McLean C.S., Erturk M., Jennings R., Ni Challanain D., Minson A.C., Duncan I., Boursnell M.E.G., Inglis S.C. Protective vaccination against primary and recurrent disease caused by herpes simplex virus (HSV) type 2 using a genetically disabled HSV-1. J. Inf. Dis. 170:1994;1100-1109.
    • (1994) J. Inf. Dis. , vol.170 , pp. 1100-1109
    • McLean, C.S.1    Erturk, M.2    Jennings, R.3    Ni Challanain, D.4    Minson, A.C.5    Duncan, I.6    Boursnell, M.E.G.7    Inglis, S.C.8
  • 38
    • 0025164764 scopus 로고
    • Six amino acids from the retroviral gene gag greatly enhance the transforming potential of the oncogene v-erb-B
    • Bruskin A., Jackson J., Bishop J.M., McCarley D.J., Schatzman R.C. Six amino acids from the retroviral gene gag greatly enhance the transforming potential of the oncogene v-erb-B. Oncogene. 5:1990;15-24.
    • (1990) Oncogene , vol.5 , pp. 15-24
    • Bruskin, A.1    Jackson, J.2    Bishop, J.M.3    McCarley, D.J.4    Schatzman, R.C.5
  • 39
    • 0021910003 scopus 로고
    • Distinctive effects of the viral oncogenes myc, erb, fps and src on the differentiation program of quail myogenetic cells
    • Falcone G., Tato F., Alema S. Distinctive effects of the viral oncogenes myc, erb, fps and src on the differentiation program of quail myogenetic cells. Proc. Nat. Acad. Sci. USA. 82:1985;426-430.
    • (1985) Proc. Nat. Acad. Sci. USA , vol.82 , pp. 426-430
    • Falcone, G.1    Tato, F.2    Alema, S.3
  • 40
  • 41
    • 0028297389 scopus 로고
    • Response of normal and oncogene-transformed human mammary epithelial cells to transforming growth factor β1 (TGF-β1): Lack of growth inhibitory effect on cells expressing the simian virus 40 large T-antigen
    • Basolo F., Fiore L., Ciardiello F., Calvo S., Fontanini G., Conaldi P.G., Toniolo A. Response of normal and oncogene-transformed human mammary epithelial cells to transforming growth factor β1 (TGF-β1): lack of growth inhibitory effect on cells expressing the simian virus 40 large T-antigen. Int. J. Cancer. 56:1994;736-742.
    • (1994) Int. J. Cancer , vol.56 , pp. 736-742
    • Basolo, F.1    Fiore, L.2    Ciardiello, F.3    Calvo, S.4    Fontanini, G.5    Conaldi, P.G.6    Toniolo, A.7
  • 42
    • 0027943854 scopus 로고
    • V-sis oncogene-induced transformation of human fibroblasts into cells capable of forming benign tumors
    • Yang D., Kohler S.K., Maher V.M., McCormick J.J. v-sis oncogene-induced transformation of human fibroblasts into cells capable of forming benign tumors. Carcinogenesis. 15:1994;2167-2175.
    • (1994) Carcinogenesis , vol.15 , pp. 2167-2175
    • Yang, D.1    Kohler, S.K.2    Maher, V.M.3    McCormick, J.J.4
  • 43
    • 0028058894 scopus 로고
    • Production of host shutoff-defective mutants of herpes simplex virus type 1 by inactivation of the UL13 gene
    • Overton H., McMillan D., Hope L., Wong-Kai-In P. Production of host shutoff-defective mutants of herpes simplex virus type 1 by inactivation of the UL13 gene. Virology. 202:1994;97-106.
    • (1994) Virology , vol.202 , pp. 97-106
    • Overton, H.1    McMillan, D.2    Hope, L.3    Wong-Kai-In, P.4
  • 44
    • 0031947857 scopus 로고    scopus 로고
    • The quantity of latent viral DNA correlates with the relative rates at which Herpes simplex virus types 1 and 2 cause recurrent genital outbreaks
    • Lekstrom-Himes J.A., Pesnicak L., Straus S.E. The quantity of latent viral DNA correlates with the relative rates at which Herpes simplex virus types 1 and 2 cause recurrent genital outbreaks. J. Virol. 72:1998;2760-2764.
    • (1998) J. Virol. , vol.72 , pp. 2760-2764
    • Lekstrom-Himes, J.A.1    Pesnicak, L.2    Straus, S.E.3
  • 45
    • 0024537137 scopus 로고
    • Immediate-early regulatory gene mutants define different stages in the establishment and reactivation of herpes simplex virus latency
    • Lieb D.A., Coen D.M., Bograd C.L., Hicks K.A., Yager D.R., Knipe D.M., Tyler K.L., Schaffer P.A. Immediate-early regulatory gene mutants define different stages in the establishment and reactivation of herpes simplex virus latency. J. Virol. 63:1989;759-768.
    • (1989) J. Virol. , vol.63 , pp. 759-768
    • Lieb, D.A.1    Coen, D.M.2    Bograd, C.L.3    Hicks, K.A.4    Yager, D.R.5    Knipe, D.M.6    Tyler, K.L.7    Schaffer, P.A.8


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