Epitope-specific cytotoxic T lymphocyte induction by minigene DNA immunization

Vaccine

Volumn 17, Issue 15-16, 1999, Pages 2081-2088

  Iwasaki, Akiko ^a   Dela Cruz, Charles S ^a   Young, Alex R ^a   Barber, Brian H ^a  

^a UNIVERSITY OF TORONTO   (Canada)

Author keywords

Cytotoxic T lymphocyte; DNA vaccine; Minigene

Indexed keywords

DNA VACCINE; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1;

ANIMAL CELL; ANIMAL EXPERIMENT; ANTIGEN RECOGNITION; ARTICLE; CYTOTOXIC T LYMPHOCYTE; FEMALE; IMMUNIZATION; LYMPHOCYTE ACTIVATION; MOUSE; NONHUMAN; PRIORITY JOURNAL;

ANIMALS; ANTIBODIES, VIRAL; ANTIGEN PRESENTATION; BIOLISTICS; CYTOKINES; EPITOPES, T-LYMPHOCYTE; FEMALE; GENES, VIRAL; HISTOCOMPATIBILITY ANTIGENS CLASS I; INJECTIONS, INTRAMUSCULAR; MICE; MICE, INBRED STRAINS; NUCLEOPROTEINS; ORTHOMYXOVIRIDAE; ORTHOMYXOVIRIDAE INFECTIONS; PEPTIDE FRAGMENTS; PLASMIDS; PROTEIN SORTING SIGNALS; RECOMBINANT PROTEINS; RNA-BINDING PROTEINS; T-LYMPHOCYTES, CYTOTOXIC; TUMOR CELLS, CULTURED; VACCINES, DNA; VIRAL CORE PROTEINS;

EID: 0033537871     PISSN: 0264410X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0264-410X(98)00411-3     Document Type: Article

References (18)

1. Donnelly J.J., Ulmer J.B., Shiver J.W., Liu M.A. DNA vaccines. Ann Rev Immunol. 15:1997;617-648.
2. Corr M., Lee D.J., Carson D.A., Tighe H. Gene vaccination with naked plasmid DNA: Mechanism of CTL priming. J Exp Med. 184:1996;1555-1560.
3. Iwasaki A., Torres C.A.T., Ohashi P.S., Robinson H.L., Barber B.H. Both gene gun and intramuscular injection of plasmid DNA induce cytotoxic T-lymphocytes via bone marrow derived antigen presenting cells. J Immunol. 159:1997;11-14.
4. Robinson W.E. Jr., Kawamura T., Lake D., Masuho Y., Mitchell W.M., Hersh E.M. Antibodies to the primary immunodominant domain of human immunodeficiency virus type 1 (HIV-1) glycoprotein gp41 enhance HIV-1 infection in vitro. J Virol. 64:1990;5301-5305.
5. Robinson W.E. Jr., Montefiori D.C., Mitchell W.M. Antibody-dependent enhancement of human immunodeficiency virus type 1 infection. Lancet. 1:1988;790-794.
6. Mazzoli S., Trabattoni D., Lo Caputo S., Piconi S., Ble C., Meacci F., Ruzzante S., Salvi A., Semplici F., Longhi R., Fusi M.L., Tofani N., Biasin M., Villa M.L., Mazzotta F., Clerici M. HIV-specific mucosal and cellular immunity in HIV-seronegative partners of HIV-seropositive individuals. Nat Med. 3:1997;1250-1257.
7. Rowland-Jones S., Sutton J., Ariyoshi K., Dong T., Gotch F., McAdam S., Whitby D., Sabally S., Gallimore A., Corrah T., Takiguchi M., Schultz T., McMichael A., Whittle H. HIV-specific cytotoxic T-cells in HIV-exposed but uninfected Gambian women. Nat Med. 1:1995;59-64.
8. Corr M., Tighe H., Lee D., Dudler J., Trieu M., Brinson D.C., Carson D.A. Costimulation provided by DNA immunization enhances antitumor immunity. J Immunol. 159:1997;4999-5004.
9. Ciernik F.I., Berzofsky J.A., Carbone D.P. Induction of cytotoxic T lymphocytes and antitumour immunity with DNA vaccine expressing single T cell epitopes. J Immunol. 156:1996;2369-2375.
10. Restifo N.P., Bacik I., Irvine K.R., Yewdell J.W., McCabe B.J., Anderson R.W., Eisenlohr L.C., Rosenberg S.A., Bennink J.R. Antigen processing in vivo and the elicitation of primary CTL responses. J Immunol. 154:1995;4414-4422.
11. Iwasaki A., Stiernholm B.J., Chan A.K., Berinstein N.L., Barber B.H. Enhanced CTL responses mediated by plasmid DNA immunogens encoding costimulatory molecules and cytokines. J Immunol. 158:1997;4591-4601.
12. Iwasaki A., Barber B.H. Induction by DNA immunization of a protective antitumor cytotoxic T lymphocyte response against a minimal-epitope-expressing tumor. Cancer Immunol Immunolther. 45:1998;273-279.
13. Eisenbraun M.D., Fuller D.J., Haynes J.R. Examination of parameters affecting the elicitation of humoral immune responese by particle bombardment-mediated genetic immunization. DNA Cell Biol. 12:1993;791-797.
14. Casares S., Inaba K., Brumeanu T.D., Steinman R.M., Bona C.A. Antigen presentation by dendritic cells after immunization with DNA encoding a major histocompatibility complex class II-restricted viral epitope. J Exp Med. 186:1997;1481-1486.
15. Fu T., Ulmer J., Caulfield M., Deck R., Friedman A., Wang S., Liu X., Donnelly J., Liu M. Priming of cytotoxic T lymphocytes by DNA vaccines: requirement for professional antigen presenting cells and evidence for antigen transfer from myocytes. Mol Med. 3:1997;362-371.
16. Schodin B.A., Tsomides T.J., Kranz D.M. Correlation between the number of T cell receptors required for T cell activation and TCR-ligand affinity. Immunity. 5:1996;137-146.
17. Moerschell R.P., Hosokawa Y., Tsunasawa S., Sherman F. The specificities of yeast methionine aminopeptidase and acetylation of amino-terminal methionine in vivo. Processing of altered iso-1-cytochromes c created by oligonucleotide transformation. J Biol Chem. 265:1990;19638-19643.
18. Rodriguez F., An L.L., Harkins S., Zhang J., Yokoyama M., Widera G., Fuller J.T., Kincaid C., Campbell I.L., Whitton J.L. DNA immunization with minigenes: low frequency of memory cytotoxic T lymphocytes and inefficient antiviral protection are rectified by ubiquitination. J Virol. 72:1998;5174-5181.