Structure-activity relationships of a series of benzothiophene-derived NPY Y1 antagonists: Optimization of the C-2 side chain

Bioorganic and Medicinal Chemistry Letters

Volumn 9, Issue 3, 1999, Pages 475-480

  Britton, Thomas C ^a   Spinazze, Patrick G ^a   Hipskind, Philip A ^a   Zimmerman, Dennis M ^a   Zarrinmayeh, Hamideh ^a   Schober, Douglas A ^a   Gehlert, Donald R ^a   Bruns, Robert F ^a  

^a ELI LILLY AND COMPANY   (United States)

Author keywords

Antagonists; Benzothiophenes; Neurologically active compds; Receptors

Indexed keywords

NEUROPEPTIDE Y RECEPTOR; NEUROPEPTIDE Y RECEPTOR ANTAGONIST;

ARTICLE; BINDING AFFINITY; CHEMICAL MODIFICATION; DRUG MECHANISM; DRUG RECEPTOR BINDING; DRUG STRUCTURE; STRUCTURE ACTIVITY RELATION; STRUCTURE ANALYSIS;

RECEPTORS, NEUROPEPTIDE Y; RECOMBINANT PROTEINS; STRUCTURE-ACTIVITY RELATIONSHIP; THIOPHENES;

EID: 0033535122     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(99)00019-0     Document Type: Article

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