SCH 57790: A novel M2 receptor selective antagonist

Life Sciences

Volumn 64, Issue 6-7, 1999, Pages 535-539

  Lachowicz, Jean E ^a   Lowe, Derek L ^a   Duffy, Ruth A ^a   Ruperto, Vilma ^a   Taylor, Lisa A ^a   Guzik, Henry ^a   Brown, Joan ^a   Berger, Joel G ^a   Tice, Melissa ^a   McQuade, Robert ^a   Kozlowski, Joseph ^a   Clader, John ^a   Strader, Catherine D ^a   Murgolo, Nicholas ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

Author keywords

Acetylcholine; Alzheimer's disease; M2 receptor antagonist; SCH 57790

Indexed keywords

4 CYCLOHEXYL ALPHA [4 [(4 METHOXYPHENYL)SULFINYL]PHENYL] 1 PIPERAZINEACETONITRILE; ACETYLCHOLINE; ACETYLCHOLINESTERASE; MUSCARINIC M1 RECEPTOR; MUSCARINIC M2 RECEPTOR; MUSCARINIC M2 RECEPTOR ANTAGONIST; OXOTREMORINE; PIPERAZINE DERIVATIVE; PIPERIDINE; QUINUCLIDINYL BENZILATE; UNCLASSIFIED DRUG;

ACETYLCHOLINE RELEASE; ALZHEIMER DISEASE; ANIMAL CELL; CHO CELL; CHOLINERGIC NERVE CELL; COGNITIVE DEFECT; CONFERENCE PAPER; DRUG MECHANISM; DRUG RECEPTOR BINDING; LEARNING; MEMORY; NERVE CELL NECROSIS; NONHUMAN;

ACETYLCHOLINE; ADENYLATE CYCLASE; ALZHEIMER DISEASE; ANIMALS; BINDING SITES; CHO CELLS; CRICETINAE; CYCLIC AMP; FORSKOLIN; HUMANS; MUSCARINIC AGONISTS; MUSCARINIC ANTAGONISTS; OXOTREMORINE; PIPERAZINES; QUINUCLIDINYL BENZILATE; RECEPTOR, MUSCARINIC M2; RECEPTORS, MUSCARINIC; TRANSFECTION;

ANIMALIA;

EID: 0033534393     PISSN: 00243205     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0024-3205(98)00598-0     Document Type: Conference Paper

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