Anti-aldol reactions of lactate-derived ketones. Application to the synthesis of (-)-tetrahydrolipstatin

Tetrahedron Letters

Volumn 40, Issue 2, 1999, Pages 393-394

  Paterson, I ^a   Doughty, V A ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ALDEHYDE; ANTIOBESITY AGENT; ENZYME INHIBITOR; KETONE DERIVATIVE; LACTIC ACID; LACTONE DERIVATIVE; PANCREAS ENZYME; TETRAHYDROLIPSTATIN; TRIACYLGLYCEROL LIPASE;

ARTICLE; CHEMICAL REACTION; CHEMICAL STRUCTURE; DIASTEREOISOMER; ENANTIOMER; ENZYME INHIBITION; HUMAN; OBESITY; STEREOCHEMISTRY; SYNTHESIS;

EID: 0033534342     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0040-4039(98)02321-1     Document Type: Article

References (23)

1. Weibel E.K. Hadvary P. Hochuli E. Kupfer E. Lengsfeld H. J. Antibiot. 40 1987 1081
2. Hochuli E. Kupfer E. Maurer R. Meister W. Mercadel Y. Schmidt K. J. Antibiot. 40 1987 1086
3. Hadvary P. Lengsfeld H. Wolfer H. Biochem. J. 256 1988 357
4. Borgström B. Biochim. Biophys. Acta 962 1988 308
5. Barbier P. Schneider F. Helv. Chim. Acta 70 1987 196
6. Barbier P. Schneider F. Widmer U. Helv. Chim. Acta 70 1987 1412
7. Barbier P. Schneider F. J. Org. Chem. 53 1988 1218
8. Pons J. Kocienski P.J. Tetrahedron Lett. 30 1989 1833
9. Fleming I. Lawrence N.J. Tetrahedron Lett. 31 1990 3645
10. Chadha N.K. Batcho A.D. Tang P.C. Courtney L.F. Cook C.M. Wovkulich P.M. Uskokovic M.R. J. Org. Chem. 56 1991 4714
11. Case-Green S.C. Davies S.G. Hedgecock C.J.R. Synlett 1991 781
12. Hanessian S. Tehim A. Chen P. J. Org. Chem. 58 1993 7768
13. Pommier A. Pons J. Kocienski P.J. Wong L. Synthesis 1994 1294
14. Giese B. Roth M. J. Braz. Chem. Soc. 7 1996 243
15. Fleming I. Lawrence N.J. J. Chem. Soc., Perkin Trans. 1 1998 2679
16. Paterson I. Hulme A.N. J. Org. Chem. 60 1995 3288
17. Paterson I. Wallace D.J. Cowden C.J. Synthesis 639 1998
18. Paterson I. Wallace D.J. Velazquez S.M. Tetrahedron Lett. 35 1994 9083
19. Paterson I. Wallace D.J. Tetrahedron Lett. 35 1994 9087
20. For some applications, see: Paterson I. Wallace D.J. Tetrahedron Lett. 35 1994 9477
21. Paterson I. Feßner K. Finlay M.R.V. Tetrahedron Lett. 38 1997 4301
22. Williams M.J. Jobson R.B. Yasuda N. Marchesini G. Dolling U.-H. Grabowski E.J.J. Tetrahedron Lett. 36 1995 5461
23. Bal B.S. Childers W.E. Pinnick H.W. Tetrahedron 37 1981 2091