Analysis of cytokine dynamics in corneal allograft rejection

Proceedings of the Royal Society B: Biological Sciences

Volumn 266, Issue 1434, 1999, Pages 2217-2223

  Chan, Cliburn C W ^a   Stark, Jaroslav ^a   George, Andrew J T ^a,b  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b HAMMERSMITH HOSPITAL   (United Kingdom)

Author keywords

Corneal transplantation; Cytokine network; Mathematical model; Nonlinear dynamics; Oscillations; Tumour necrosis factor

Indexed keywords

CYTOKINE; TUMOR NECROSIS FACTOR ALPHA;

AQUEOUS HUMOR; ARTICLE; CORNEA TRANSPLANTATION; EXCITABILITY; GRAFT REJECTION; HYSTERESIS; MATHEMATICAL ANALYSIS; MATHEMATICAL MODEL; NEGATIVE FEEDBACK; OSCILLATION; PRIORITY JOURNAL; RABBIT;

ORYCTOLAGUS CUNICULUS;

EID: 0033533958     PISSN: 09628452     EISSN: 14712970     Source Type: Journal    
DOI: 10.1098/rspb.1999.0911     Document Type: Article

References (23)

1. Amiot, F., Boussadia, O., Cases, S., Fitting, C., Lebastard, M., Cavaillon, J.-M., Milon, G. & Dautry, F. 1997 Mice heterozygous for a deletion of the tumor necrosis factor-α and lymphotoxin-α genes: biological importance of a nonlinear response of tumor necrosis factor-α to gene dosage. Eur. J. Immunol. 27, 1035-1042.
2. Dallman, M. J. 1993 Cytokines as mediators of organ graft rejection and tolerance. Curr. Opin. Immunol. 5, 788-793.
3. Ferguson, T. A., Fletcher, S., Herndon, J. & Griffith, T. S. 1995 Neuropeptides modulate immune deviation induced via the anterior chamber of the eye. J. Immunol. 155, 1746-1756.
4. Ferguson, T. A., Herndon, J. M. & Dube, P. 1994 The immune response and the eye: a role for TNFα in anterior chamber-associated immune deviation. Invest. Ophthalmol. Vis. Sci. 35, 2643-2651.
5. Fisher, C. J., Agosti, J. M., Opal, S. M., Lowry, S. F., Balk, R. A., Sadoff, J. C., Abraham, E., Schein, R. M. & Benjamin, E. for the Soluble TNF Receptor Sepsis Study Group 1996 Treatment of septic shock with the tumor necrosis factor receptor:Fc fusion protein. New Engl. J. Med. 334, 1697-1702.
6. Glendinning, P. 1994 Stability, instability and chaos: an introduction to the theory of nonlinear differential equations, Cambridge texts in applied mathematics. Cambridge University Press.
7. Griffith, T. S., Brunner, T., Fletcher, S. M., Green, D. R. & Ferguson, T. A. 1995 Fas ligand-induced apoptosis as a mechanism of immune privilege. Science 270, 1189-1192.
8. Heaney, M. L. & Golde, D. W. 1996 Soluble cytokine receptors. Blood 87, 847-857.
9. Kalden, J., Breedveld, F., Burkhardt, H. & Burmester, G. 1998 Immunological treatment of autoimmune diseases. Adv. Immunol. 68, 333-418.
10. Kuznetsov, Y. A. 1995 Elements of applied bifurcation theory, applied mathematical sciences series. Berlin: Springer.
11. Nickerson, P., Steiger, J., Zheng, X., Steele, A., Steurer, W., Roy-Chaudhury, P. & Strom, T. 1997 Manipulation of cytokine networks in transplantation: false hope or realistic opportunity for tolerance? Transplantation 63, 489-494.
12. Niederkorn, J. Y. 1990 Immune privilege and immune regulation in the eye. Adv. Immunol. 48, 191-226.
13. Philip, R. & Epstein, L. B. 1986 Tumour necrosis factor as immunomodulator and mediator of monocyte cytotoxicity induced by itself, γ-interferon and interleukin-1. Nature 323, 86-89.
14. Prieur, A., Lombard, P. R. & Dayer, J. 1996 Dynamics of fever and the cytokine network in systemic juvenile arthritis. Rev. Rhum. Engl. Ed. 63, 163-170.
15. Rayner, S., King, W., Isaacs, J., Hale, G., George, A. & Larkin, D. 1999 Pulsatile local bioactive tumor necrosis factor in allograft rejection. Invest. Ophthalmol. Vis. Sci. (Submitted.)
16. Rooney, M., David, J., Symons, J., Giovine, F. D., Varsani, H. & Woo, P. 1995 Inflammatory cytokine responses in juvenile chronic arthritis. Br. J. Rheumatol. 34, 454-460.
17. Schattner, A., Lachmi, M., Livneh, A., Pras, M. & Hahn, T. 1991 Tumour necrosis factor in familial mediterranean fever. Am. J. Med. 90, 434-438.
18. Segel, L. A. 1984 Modeling dynamic phenomena in molecular and cellular biology. Cambridge University Press.
19. Streitein, J. W., Wilbanks, G. A. & Cousins, S. W. 1992 Immunoregulatory mechanisms of the eye. J. Neuroimmunol. 39, 185-200.
20. Strieter, R. M., Kunkel, S. L. & Bone, R. C. 1993 Role of tumor necrosis factor-α in disease states and inflammation. Crit. Care Med. 21, S447-S463.
21. Tracey, K. J. & Cerami, A. 1994 Tumour necrosis factor: a pleiotropic cytokine and therapeutic target. A. Rev. Med. 45, 491-503.
22. Williams, K. A. & Coster, D. J. 1997 Rethinking immunological privilege: implications for corneal and limbal stem cell transplantation. Mol. Med. Today 11, 495-501.
23. Williams, K., Roder, D., Esterman, A., Muehlberg, S. & Coster, D. 1992 Factors predictive of corneal graft survival, report from the Australian Corneal Graft Registry. Opthalmology 99, 403-414.