Numerical simulation of motility patterns of the small bowel. II. Comparative pharmacological validation of a mathematical model

Journal of Theoretical Biology

Volumn 200, Issue 3, 1999, Pages 261-290

  Miftakhov, R N ^a   Abdusheva, G R ^b   Christensen, J ^a  

^a UNIVERSITY OF IOWA HOSPITALS AND CLINICS   (United States)

^b KAZAN FEDERAL UNIVERSITY   (Russian Federation)

Author keywords

[No Author keywords available]

Indexed keywords

1,4 DIHYDRO 2,6 DIMETHYL 5 NITRO 4 [2 (TRIFLUOROMETHYL)PHENYL] 3 PYRIDINECARBOXYLIC ACID METHYL ESTER; ADENOSINE TRIPHOSPHATASE (CALCIUM); BENZODIAZEPINE DERIVATIVE; CALCIUM CHANNEL; CYCLOPIAZONIC ACID; DIAZOXIDE; ERYTHROMYCIN; MOTILIN; NIFEDIPINE; NIMODIPINE; RYANODINE; THAPSIGARGIN; VERAPAMIL;

ARTICLE; INTESTINE MOTILITY; MATHEMATICAL MODEL; PRIORITY JOURNAL; SARCOPLASMIC RETICULUM; SIMULATION; SMALL INTESTINE;

EID: 0033533732     PISSN: 00225193     EISSN: None     Source Type: Journal    
DOI: 10.1006/jtbi.1999.0991     Document Type: Article

References (50)

1. BERTRAND P. P., GALLIGAN J. J. Alfaxalone, pentobarbital and diazepam potentiate γ -aminobutyric acid-induced depolarizations in single myenteric neurons of guinea-pig intestine. J. Pharmacol. Exp. Ther. 262:1992;677-681.
2. Areceptor-mediated stimulation of non-adrenergic non-cholinergic neurones in the dog ileocolonic junction. Br. J. Pharmacol. 101:1990;460-464.
3. 2+channels. Naunyn-Schmiedeberg's Arch. Pharmacol. 351:1993;40-45.
4. 2+channel antagonists. Trends Pharmacol. Sci. 13:1992;256-262.
5. 2+role in myogenic and neurogenic activties of canine ileum circular muscle. Am. J. Physiol. 271:1996;G1053-G1066.
6. CHEN Q., VAN BREEMEN C. Receptor mediated disruption of the smooth muscle SR buffer barrier function. Jpn J. Pharmacol. 58:1992;60.
7. CHERUBINI E., NORTH R. A. Inhibition of calcium spikes and transmitter release by γ -aminobutyric acid in the guinea pig myenteric plexus. Br. J. Pharmacol. 82:1984;101-105.
8. CHRISTENSEN J., DENT J. R., MALAGELADA J. R., WINGATE D. L. Pseudo-obstruction. Gastroenterol. Int. 3:1990;107-119.
9. COSTA A., ALESSIANI M., DE PONTI F., SPADA M., MERLI M., ZANOLA S., BARBERA D., RADEMACHER J., DRIVAS E., CREMA A. Stimulatory effect of FK506 and erythromycin on pig intestinal motility. Transplant. Proc. 28:1996;2571-2572.
10. 13] porcine motilin. Eur. J. Pharmacol. 286:1995;241-247.
11. DESSY C., GODFRAIND T. The effect of L-type calcium channel modulators on the mobilization of intracellular calcium stores in guinea-pig intestinal smooth muscle. Br. J. Pharmacol. 119:1996;142-148.
12. Bagonists on small intestine motility in rats. Eur. J. Pharmacol. 150:1988;163-169.
13. FARRUGIA G., MACIELAG M. J., PEETERS T. L., SARR M. G., GALDES A., SZURSZEWSKI J. H. Motilin and OHM-11526 activate a calcium current in human and canine jejunal circular smooth muscle. Am. J. Physiol. 36:1997;G404-G412.
14. 2+current in ileal cells by cyclopiazonic acid and ryanodine. Eur. J. Pharmacol. 243:1993;19-24.
15. GANG L. U., SARR M. G., SZURSZEWSKI. Effect of motilin and erythromycin on calcium-activated potassium channels in rabbit colonic myocytes. Gastroenterology. 114:1998;748-754.
16. Breceptor-mediated mechanisms in human intestine in vitro. Eur. J. Pharmacol. 217:1992;9-14.
17. HARADA N., CHIJIWA Y., MISAWA T., YOSHINAGA M., NAWATA H. Direct contractile effect of motilin on isolated smooth muscle cells of guinea pig small intestine. Life Sci. 51:1992;1381-1387.
18. HILLS J. M., JESSEN K. R., MIRSKY R. An immunohistochemical study of the distribution of enteric GABA-containing neurons in the rat and guinea-pig intestine. Neuroscience. 22:1987;301-312.
19. HISAYAMA T., TAKAYANAGI I. Ryanodine: its possible mechanism of action in the caffeine-sensitive calcium store of smooth muscle. Pfluegers Arch. 412:1988;376-381.
20. IINO M., KOBAYASHI T., ENDO M. Use of ryanodine for functional removal of the calcium store in smooth muscle cells of the guinea-pig. Biochem. Biophys. Res. Commun. 152:1988;417-422.
21. 2+release from the sacroplasmic reticulum of mammalian smooth muscle cells. Biomed. Biochem. Acta. 48:1989;S364-S369.
22. 2+channel probe: characterization of two equipotent diastereomers with opposite allosteric properties. Mol. Pharmacol. 41:1992;298-307.
23. itransients in single smooth muscle cells of guinea-pig ileum. Br. J. Pharmacol. 122:1997;477-486.
24. LEBRUN P., FONTAINE J. Relaxation response to pinacidil and diazoxide in the mouse isolated distal colon. Pharmacology. 40:1990;21-26.
25. LESH R. E., NIXON G. F., FLEISCHER S., AIREY J. A., SOMLYO A. P., SOMLYO A. V. Localization of ryanodine receptors in smooth muscle. Cir. Res. 82:1998;175-185.
26. MATTHIJS G., PEETERS T. L., VANTRAPPEN G. Effect of different calcium modulators on motilin-induced contractions of the rabbit duodenum. Comparison with acetylcholine. Regul. Peptides. 21:1988;321-330.
27. MATTHIJS G., PEETERS T. L., VANTRAPPEN G. The role of intracellular calcium stores in motilin induced contractions of the longitudinal muscle of the rabbit duodenum. Naunyn-Schmiedebergs Arch. Pharmacol. 339:1989;32-39.
28. +-channel agonists and antagonists on myoelectrical activity of a locus of the small bowel. Biol. Cybernet. 75:1996a;331-338.
29. MIFTAKHOV R. N., ABDUSHEVA G. R. Numerical simulation of excitation-contraction coupling in a locus of the small bowel. Biol. Cybernet. 74:1996b;455-467.
30. MIFTAKHOV R. N., ABDUSHEVA G. R., CHRISTENSEN J. Numerical simulation of motility patterns of the small bowel. I. Formulation of a mathematical model. J. theor. Biol. 197:1999;89-112.
31. Breceptors in guinea pig distal colon. Eur. J. Pharmacol. 230:1993;187-193.
32. 3H)-muscimol in the rat intestinal musculature. Pharmacology. 42:1991;103-110.
33. 2+stores in ileal smooth muscle of the rat. Br. J. Pharmacol. 114:1995;1165-1179.
34. OHYA Y., TERADA K., KITAMURA K., KURIYAMA H. Membrane currents recorded from a fragment rabbit intestinal smooth muscle cell. Am. J. Physiol. 251:1986;C335-C346.
35. ONG J., KERR D. I. B. Comparison of GABA-induced responses in various segments of the guinea pig intestine. Eur. J. Pharmacol. 134:1987;349-353.
36. 2+store in protal vein smooth muscle cells. J. Biol. Chem. 268:1993;3866-3872.
37. 2+-ATPase of sarcoplasmic reticulum. J. Biol. Chem. 264:1989;17816-17823.
38. STAPELFELDT W. H., PARKMAN H. P., SZURSZEWSKI J. H. The electrophysiological effects of endogenous GABA in the guinea-pig inferior mesenteric ganglion. J. Physiol. 471:1993;175-189.
39. STRUNZ U., DOMSCHKE W., MITZNEGG P. Analysis of the motor effects of 13-norleucine motilin on the rabbit, guinea pig, rat and human alimentary tract in vivo. Gastroenterology. 68:1975;1485-1491.
40. 2+-dependend K currents in guinea-pig smooth muscle cells. Br. J. Pharmacol. 107:1992;134-140.
41. 2+entry in rat ileal smooth muscle. Eur. J. Pharmacol. 313:1996;151-158.
42. Areceptor-mediated response in the enteric nervous system of guinea-pig small intestine. J. Pharmacol. Exp. Ther. 245:1988;250-256.
43. USOWICZ M. M., GIGG M., JONES L. M. E., CHEUNG C. W., HARTLEY S. A. Allosteric interactions at L-type Calcium channels between FPL 64176 and the enantiomers of the dihydropyridine Bay K 8644. J. Pharmacol. Exp. Ther. 275:1995;638-645.
44. 2+-ATPase in sarcoplasmic reticulum, increases excitability in ileal smooth muscle. Br. J. Pharmacol. 110:1993;565-572.
45. 2+-ATPase inhibitor on contractile responses in skinned ileal smooth muscle. Br. J. Pharmacol. 106:1992;208-214.
46. VELASCO A., MAROTO M., DUENAS A., CARVAJAL A., FERNANDEZ DE LA GANDRA F., NIETO A. Effect of 4-aminopyridine and 3,4-diminopyridine on guinea-pig isolated ileum. J. Autonom. Pharmacol. 17:1997;53-57.
47. 1- and β -adrenoceptor effects of noradrenaline on electrical slow waves and phasic contractions of cat colon circular muscle. Br. J. Pharmacol. 116:1995;3265-3273.
48. WEBER F. H. JR., RICHARDS R. D., MCCALLUM R. W. Erythromycin: a motilin agonist and gastrointestinal prokinetic agent. Am. J. Physiol. 88:1993;485-490.
49. YAMADA K., CHEN S., ABDULLAH N. A., TANAKA M., ITO Y., INOUE R. Electrophysiological characterization of a motilin agonist, GM611, on rabbit duodenal smooth muscle. Am. J. Physiol. 34:1996;G1003-G1016.
50. Areceptor α-subunit mRNA in rat intestine. Mol. Brain Res. 39:1996;241-244.