Radical-based asymmetric synthesis: An iterative approach to 1, 3, 5, ... (2n + 1) polyols

Organic Letters

Volumn 1, Issue 7, 1999, Pages 1057-1059

  Garner, Philip ^a   Anderson, James T ^a  

^a CASE WESTERN RESERVE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

POLYMER; POLYOL;

ARTICLE; CHEMICAL STRUCTURE; CHEMISTRY; STEREOISOMERISM; SYNTHESIS;

MOLECULAR STRUCTURE; POLYMERS; STEREOISOMERISM;

EID: 0033533649     PISSN: 15237060     EISSN: None     Source Type: Journal    
DOI: 10.1021/ol990188v     Document Type: Article

References (22)

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17. HOTT = (S-1-oxido-2-pyridinyl) 1,1,3,3-tetramethylthiouronium hexafluorophosphate: Garner, P.; Anderson, J. T.; Dey, S.; Youngs, W. J.; Galat, K. J. Org. Chem. 1998, 63, 5732.
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19. 2/EtOAc; flash chromatography.
20. 2O, buffered aqueous HOAc; (8) excess MeMgCl, THF, 0 °C → rt; (9) NaH, MeI, THF.
21. 2 (isolate 14 and/or 16 by flash chromatography. 86-88% yield); (6) DMP, catalytic TsOH.
22. Rychnovsky, S. D.; Grieseraber, G.; Schlegel, R. J. Am. Chem. Soc. 1995, 177, 197.