-
1
-
-
77049220618
-
Affinity and intrinsic efficacy in the theory of competitive inhibition. Part I. Problems and theory
-
Ariëns, E. J. (1954). Affinity and intrinsic efficacy in the theory of competitive inhibition. Part I. Problems and theory. Arch. Int. Pharmacodyn. Ther. 99, 32-49.
-
(1954)
Arch. Int. Pharmacodyn. Ther.
, vol.99
, pp. 32-49
-
-
Ariëns, E.J.1
-
2
-
-
8044237686
-
An attempt to study the effect of chemical structure on the affinity and efficacy of compounds related to acetylcholine
-
Barlow, R. B., Scott, K. A. & Stephenson, R. P. (1967). An attempt to study the effect of chemical structure on the affinity and efficacy of compounds related to acetylcholine. Br. J. Pharmacol. 21, 509-522.
-
(1967)
Br. J. Pharmacol.
, vol.21
, pp. 509-522
-
-
Barlow, R.B.1
Scott, K.A.2
Stephenson, R.P.3
-
3
-
-
0002461492
-
Methods in binding studies
-
Yamamura, H. I., Enna, S. J. & Kuhar, M. J., eds. New York: Raven Press
-
Bennett, J. P. (1978). Methods in binding studies. In: Neurotransmitter Receptor Binding (Yamamura, H. I., Enna, S. J. & Kuhar, M. J., eds) pp. 57-90. New York: Raven Press.
-
(1978)
Neurotransmitter Receptor Binding
, pp. 57-90
-
-
Bennett, J.P.1
-
4
-
-
0021058380
-
Operational models of pharmacological agonism
-
Black, J. W. & Leff, P. (1983). Operational models of pharmacological agonism. Proc. R. Soc. B. 220, 141-162.
-
(1983)
Proc. R. Soc. B.
, vol.220
, pp. 141-162
-
-
Black, J.W.1
Leff, P.2
-
5
-
-
0021990306
-
An operational model of pharmacological agonism: The effect of E/[A] curve shape on agonist dissociation constant estimation
-
Black, J. W., Leff, P., Shankley, N. P. & Wood, J. (1985). An operational model of pharmacological agonism: The effect of E/[A] curve shape on agonist dissociation constant estimation. Br. J. Pharmacol. 84, 561-571.
-
(1985)
Br. J. Pharmacol.
, vol.84
, pp. 561-571
-
-
Black, J.W.1
Leff, P.2
Shankley, N.P.3
Wood, J.4
-
6
-
-
0017295075
-
β-Adrenergic receptor interactions. Direct comparison of receptor interaction and biological activity
-
Brown, E. M., Fedak, S. A., Woodard, C. J., Aurbach, G. D. & Rodbard, D. (1976). β-Adrenergic receptor interactions. Direct comparison of receptor interaction and biological activity. J. Biol. Chem. 251, 1239-1246.
-
(1976)
J. Biol. Chem.
, vol.251
, pp. 1239-1246
-
-
Brown, E.M.1
Fedak, S.A.2
Woodard, C.J.3
Aurbach, G.D.4
Rodbard, D.5
-
7
-
-
0013579965
-
Receptor binding methodologies and analysis
-
O'Brian, R. A., ed. New York: Dekker
-
Burt, D. R. (1986). Receptor binding methodologies and analysis. In: Receptor Binding in Drug Research (O'Brian, R. A., ed.) pp. 3-30. New York: Dekker.
-
(1986)
Receptor Binding in Drug Research
, pp. 3-30
-
-
Burt, D.R.1
-
8
-
-
0002134457
-
Affinity, efficacy, and receptor classification: Is the classical theory stil useful?
-
Black, J. W., Jenkinson, D. H. & Gerskowitch, V. P., eds. New York: Alan R. Liss
-
Colquhoun, D. (1987). Affinity, efficacy, and receptor classification: Is the classical theory stil useful? In: Perspectives on Receptor Classification (Black, J. W., Jenkinson, D. H. & Gerskowitch, V. P., eds) pp. 103-114. New York: Alan R. Liss.
-
(1987)
Perspectives on Receptor Classification
, pp. 103-114
-
-
Colquhoun, D.1
-
9
-
-
0026608113
-
Drug efficacy at guanine nucleotide-binding regulatory protein-linked receptors: Thermodynamic interpretation of negative antagonism and of receptor activity in the absence of ligand
-
Costa, T., Ogino, Y., Munson, P. J., Onaran, H. O. & Rodbard, D. (1992). Drug efficacy at guanine nucleotide-binding regulatory protein-linked receptors: Thermodynamic interpretation of negative antagonism and of receptor activity in the absence of ligand. Mol. Pharmacol. 41, 549-560.
-
(1992)
Mol. Pharmacol.
, vol.41
, pp. 549-560
-
-
Costa, T.1
Ogino, Y.2
Munson, P.J.3
Onaran, H.O.4
Rodbard, D.5
-
10
-
-
0002355204
-
The use of β-haloalkylamines in the differentiation of receptors and in the determination of dissociation constants of receptor-agonist complexes
-
Harper, N. J. & Simmonds, A. B., eds. London: Academic Press
-
Furchgott, R. F. (1966). The use of β-haloalkylamines in the differentiation of receptors and in the determination of dissociation constants of receptor-agonist complexes. In: Advances in Drug Research (Harper, N. J. & Simmonds, A. B., eds) pp. 21-55. London: Academic Press.
-
(1966)
Advances in Drug Research
, pp. 21-55
-
-
Furchgott, R.F.1
-
11
-
-
84981848149
-
Comparison of dissociation constants and of relative efficacies of selective agonists acting on parasympathetic receptors
-
Furchgott, R. F. & Bursztyn, P. (1967). Comparison of dissociation constants and of relative efficacies of selective agonists acting on parasympathetic receptors. Ann. N. Y. Acad. Sci. 144, 882-889.
-
(1967)
Ann. N. Y. Acad. Sci.
, vol.144
, pp. 882-889
-
-
Furchgott, R.F.1
Bursztyn, P.2
-
12
-
-
0025298667
-
Affinities of full agonists for cardiac β-adrenoceptors calculated by use of in vitro desensitization
-
Herepath, M. L. & Broadley, K. J. (1990). Affinities of full agonists for cardiac β-adrenoceptors calculated by use of in vitro desensitization. Naunyn-Schmiedeberg's Arch. Pharmacol. 341, 525-533.
-
(1990)
Naunyn-Schmiedeberg's Arch. Pharmacol.
, vol.341
, pp. 525-533
-
-
Herepath, M.L.1
Broadley, K.J.2
-
13
-
-
0021808471
-
The quantification of relative efficacy of agonists
-
Kenakin, T. P. (1985). The quantification of relative efficacy of agonists. J. Pharmacol. Meth. 13, 281-308.
-
(1985)
J. Pharmacol. Meth.
, vol.13
, pp. 281-308
-
-
Kenakin, T.P.1
-
15
-
-
0029812311
-
The classification of seven transmembrane receptors in recombinant expression systems
-
Kenakin, T. P. (1996). The classification of seven transmembrane receptors in recombinant expression systems. Pharmacol. Rev. 48, 413-463.
-
(1996)
Pharmacol. Rev.
, vol.48
, pp. 413-463
-
-
Kenakin, T.P.1
-
17
-
-
0029823415
-
The two-state model of agonist action: Challenges to pharmacological receptor theory
-
Leff, P. (1996). The two-state model of agonist action: Challenges to pharmacological receptor theory. Proc. West. Pharmacol. Soc. 39, 67-68.
-
(1996)
Proc. West. Pharmacol. Soc.
, vol.39
, pp. 67-68
-
-
Leff, P.1
-
18
-
-
0024432963
-
Do pharmacological methods for the quantification of agonists work when the ternary complex mechanism operates?
-
Leff, P. & Harper, D. (1989). Do pharmacological methods for the quantification of agonists work when the ternary complex mechanism operates? J. Theor. Biol. 140, 381-397.
-
(1989)
J. Theor. Biol.
, vol.140
, pp. 381-397
-
-
Leff, P.1
Harper, D.2
-
19
-
-
0021845519
-
Application of the operational model of agonism to establish conditions when functional antagonism may be used to estimate agonist dissociation constants
-
Leff, P., Martin, G. R. & Morse, J. M. (1985). Application of the operational model of agonism to establish conditions when functional antagonism may be used to estimate agonist dissociation constants. Br. J. Pharmacol. 85, 655-663.
-
(1985)
Br. J. Pharmacol.
, vol.85
, pp. 655-663
-
-
Leff, P.1
Martin, G.R.2
Morse, J.M.3
-
20
-
-
0013895745
-
The mathematics of drug-receptor interactions
-
Mackay, D. (1966). The mathematics of drug-receptor interactions. J. Pharm. Pharmacol. 18, 201-222.
-
(1966)
J. Pharm. Pharmacol.
, vol.18
, pp. 201-222
-
-
Mackay, D.1
-
21
-
-
0001806350
-
A critical survey of receptor theories of drug action
-
Van Rossum, J. M., ed. New York: Springer-Verlag
-
Mackay, D. (1977). A critical survey of receptor theories of drug action. In: Kinetics of Drug Action (Van Rossum, J. M., ed.) pp. 169-254. New York: Springer-Verlag.
-
(1977)
Kinetics of Drug Action
, pp. 169-254
-
-
Mackay, D.1
-
22
-
-
0024013229
-
Continuous variation of agonist affinity constants
-
Mackay, D. (1988). Continuous variation of agonist affinity constants. Trends Pharmacol. Sci. 9, 156-157.
-
(1988)
Trends Pharmacol. Sci.
, vol.9
, pp. 156-157
-
-
Mackay, D.1
-
23
-
-
0030152114
-
Improved models for pharmacological null experiments: Calculation of drug efficacy at recombinant D1A dopamine receptors stably expressed in clonal cell lines
-
Mak, C. K., Avalos, M., Randall, P. K., Kwan, S. W., Abell, C. W., Neumeyer, J. L., Whisennand, R. & Wilcox, R. E. (1996). Improved models for pharmacological null experiments: Calculation of drug efficacy at recombinant D1A dopamine receptors stably expressed in clonal cell lines. Neuropharmacol. 35, 549-570.
-
(1996)
Neuropharmacol.
, vol.35
, pp. 549-570
-
-
Mak, C.K.1
Avalos, M.2
Randall, P.K.3
Kwan, S.W.4
Abell, C.W.5
Neumeyer, J.L.6
Whisennand, R.7
Wilcox, R.E.8
-
24
-
-
0015874796
-
Mathematics of hormone-receptor interaction. I. Basic principles
-
Rodbard, D. (1973). Mathematics of hormone-receptor interaction. I. Basic principles. Adv. Exp. Med. Biol. 36, 289-326.
-
(1973)
Adv. Exp. Med. Biol.
, vol.36
, pp. 289-326
-
-
Rodbard, D.1
-
25
-
-
0020391631
-
Important concepts of receptor theory
-
Ruffolo, R. R. Jr. (1982). Important concepts of receptor theory. J. Autonom. Pharmacol. 2, 277-295.
-
(1982)
J. Autonom. Pharmacol.
, vol.2
, pp. 277-295
-
-
Ruffolo R.R., Jr.1
-
26
-
-
0018360305
-
Receptor interactions of imidazolines. I. Affinity and efficacy for alpha adrenergic receptors in rat aorta
-
Ruffolo, R. R. Jr., Rosing, E. L. & Waddell, J. E. (1979). Receptor interactions of imidazolines. I. Affinity and efficacy for alpha adrenergic receptors in rat aorta. J. Pharmacol. Exp. Ther. 209, 429-436.
-
(1979)
J. Pharmacol. Exp. Ther.
, vol.209
, pp. 429-436
-
-
Ruffolo R.R., Jr.1
Rosing, E.L.2
Waddell, J.E.3
-
27
-
-
0010673662
-
A modification of receptor theory
-
Stephenson, R. P. (1956). A modification of receptor theory. Br. J. Pharmacol. 11, 379-393.
-
(1956)
Br. J. Pharmacol.
, vol.11
, pp. 379-393
-
-
Stephenson, R.P.1
-
28
-
-
0019411704
-
Obligatory separation of hormone binding and biological response curves in systems dependent upon secondary mediators of hormone action
-
Strickland, S. & Loeb, J. N. (1981). Obligatory separation of hormone binding and biological response curves in systems dependent upon secondary mediators of hormone action. Proc. Nat. Acad. Sci. 78, 1366-1370.
-
(1981)
Proc. Nat. Acad. Sci.
, vol.78
, pp. 1366-1370
-
-
Strickland, S.1
Loeb, J.N.2
-
29
-
-
0029012098
-
Interpretation of binding curves obtained with high receptor concentrations: Practical aid for computer analysis
-
Swillens, S. (1995). Interpretation of binding curves obtained with high receptor concentrations: Practical aid for computer analysis. Mol. Pharmacol. 47, 1197-1203.
-
(1995)
Mol. Pharmacol.
, vol.47
, pp. 1197-1203
-
-
Swillens, S.1
-
30
-
-
0030272750
-
Analysis of stimulus-response chains using nonlinear dynamics
-
Trzeciakowski, J. P. (1996). Analysis of stimulus-response chains using nonlinear dynamics. J. Pharmacol. Toxicol. Meth. 36, 103-121.
-
(1996)
J. Pharmacol. Toxicol. Meth.
, vol.36
, pp. 103-121
-
-
Trzeciakowski, J.P.1
-
31
-
-
0002093398
-
General theory of drug-receptor interactions: Drug-receptor interaction models. Calculation of drug parameters
-
Van Rossum, J. M., ed. New York: Springer-Verlag
-
van den Brink, F.G. (1977). General theory of drug-receptor interactions: Drug-receptor interaction models. Calculation of drug parameters. In: Kinetics of Drug Action (Van Rossum, J. M., ed.) pp. 169-254. New York: Springer-Verlag.
-
(1977)
Kinetics of Drug Action
, pp. 169-254
-
-
Van den Brink, F.G.1
-
32
-
-
0001344479
-
Limitations of molecular pharmacology. Some implications of the basic assumptions underlying calculations on drug-receptor interactions and the significance of biological drug parameters
-
Harper, N. J. & Simmonds, A. B., eds. London: Academic Press
-
van Rossum, J. M. (1966). Limitations of molecular pharmacology. Some implications of the basic assumptions underlying calculations on drug-receptor interactions and the significance of biological drug parameters. In: Advances in Drug Research (Harper, N. J. & Simmonds, A. B., eds) pp. 189-234. London: Academic Press.
-
(1966)
Advances in Drug Research
, pp. 189-234
-
-
Van Rossum, J.M.1
-
33
-
-
0014299372
-
Pharmacological receptors
-
Waud, D. R. (1968). Pharmacological receptors. Pharmacol. Rev. 20, 49-88.
-
(1968)
Pharmacol. Rev.
, pp. 49-88
-
-
Waud, D.R.1
-
34
-
-
0014599320
-
On the measurement of the affinity of partial agonists for receptors
-
Waud, D. R. (1969). On the measurement of the affinity of partial agonists for receptors. J. Pharmacol. Exp. Ther. 170, 117-122.
-
(1969)
J. Pharmacol. Exp. Ther.
, vol.170
, pp. 117-122
-
-
Waud, D.R.1
-
35
-
-
0030596736
-
The cubic ternary complex receptor-occupancy model III. Resurrecting efficacy
-
Weiss, J. M., Morgan, P. H., Lutz, M. W. & Kenakin, T. P. (1996). The cubic ternary complex receptor-occupancy model III. Resurrecting efficacy. J. Theor. Biol. 181, 381-397.
-
(1996)
J. Theor. Biol.
, vol.181
, pp. 381-397
-
-
Weiss, J.M.1
Morgan, P.H.2
Lutz, M.W.3
Kenakin, T.P.4
|