Mechanism of Cdk2/cyclin E inhibition by p27 and p27 phosphorylation

Biochemistry

Volumn 38, Issue 27, 1999, Pages 8713-8722

  Xu, Xu ^a   Nakano, Takayuki ^a   Wick, Scott ^a   Dubay, Marja ^a   Brizuela, Leonardo ^a  

^a GPC Biotech Inc   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIN DEPENDENT KINASE; CYCLIN E; HISTONE; PROTEIN P27;

ANIMAL CELL; ARTICLE; ENZYME INHIBITION; ENZYME MECHANISM; ENZYME REGULATION; ENZYME SPECIFICITY; ENZYME SUBSTRATE COMPLEX; HUMAN; HUMAN CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN INTERACTION; PROTEIN PHOSPHORYLATION; PROTEIN PURIFICATION;

ADENOSINE TRIPHOSPHATE; AMINO ACID SEQUENCE; ANIMALS; BINDING SITES; CDC2-CDC28 KINASES; CELL CYCLE PROTEINS; CYCLIN E; CYCLIN-DEPENDENT KINASE 2; CYCLIN-DEPENDENT KINASE INHIBITOR P27; CYCLIN-DEPENDENT KINASES; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME INHIBITORS; HUMANS; KINETICS; MACROMOLECULAR SUBSTANCES; MICE; MICROTUBULE-ASSOCIATED PROTEINS; MOLECULAR SEQUENCE DATA; PROTEIN BINDING; PROTEIN-SERINE-THREONINE KINASES; RECOMBINANT PROTEINS; SUBSTRATE SPECIFICITY; TUMOR SUPPRESSOR PROTEINS;

EID: 0033529271     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi9903446     Document Type: Article

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