An atypical form of αB-crystallin is present in high concentration in some human cataractous lenses. Identification and characterization of aberrant N- and C-terminal processing

Journal of Biological Chemistry

Volumn 274, Issue 45, 1999, Pages 32287-32294

  Jimenez Asensio, Jose ^a   Colvis, Christine M ^a   Kowalak, Jeffrey A ^b   Duglas Tabor, Yvonne ^a   Datiles, Manuel B ^a   Moroni, Maria ^a   Mura, Umberto ^c   Rao, Ch Mohan ^d   Balasubramanian, Dorairajan ^e   Janjani, Alireza ^a,f   Garland, Donita ^a  

^a NATIONAL EYE INSTITUTE   (United States)

^b EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH AND HUMAN DEVELOPMENT   (United States)

^c UNIVERSITY OF PISA   (Italy)

^d CENTRE FOR CELLULAR AND MOLECULAR BIOLOGY   (India)

^e L V PRASAD EYE INSTITUTE   (India)

^f UNIVERSITY OF MODENA AND REGGIO EMILIA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA CRYSTALLIN; BETA CRYSTALLIN; DITHIOTHREITOL; HEAT SHOCK PROTEIN; LACTALBUMIN; CRYSTALLIN; RECOMBINANT PROTEIN;

ARTICLE; CATARACT; ELECTROPHORETIC MOBILITY; ESCHERICHIA COLI; GENE EXPRESSION; HUMAN; HUMAN TISSUE; MASS SPECTROMETRY; MOLECULAR CLONING; NONHUMAN; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN PHOSPHORYLATION; AMINO ACID SEQUENCE; CHEMISTRY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; ISOELECTRIC FOCUSING; LENS; MOLECULAR GENETICS; MOLECULAR WEIGHT; PATHOLOGY; TWO DIMENSIONAL GEL ELECTROPHORESIS;

AMINO ACID SEQUENCE; CATARACT; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CLONING, MOLECULAR; CRYSTALLINS; ELECTROPHORESIS, GEL, TWO-DIMENSIONAL; HUMANS; ISOELECTRIC FOCUSING; LENS, CRYSTALLINE; MASS SPECTROMETRY; MOLECULAR SEQUENCE DATA; MOLECULAR WEIGHT; RECOMBINANT PROTEINS;

EID: 0033527449     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.274.45.32287     Document Type: Article

References (60)

1. Hoenders, H. J., and Bloemendal, H. (1983) J. Gerontol. 38, 278-286
2. Bloemendal, H. (ed) (1981) Molecular and Cellular Biology of the Eye Lens, pp. 279-405, John Wiley & Sons, Inc., New York
3. Harding, J. J., and Dilley, K. J. (1976) Exp. Eye Res. 22, 1-73
4. Groenen, P. J., Merck, K. B., de Jong, W. W., and Bloemendal, H. (1994) Eur. J. Biochem. 225, 1-19
5. Dubin, R. A., Wawrousek, E. F., and Piatigorsky, J. (1989) Mol. Cell. Biol. 9, 1083-1091
6. Bhat, S. P., and Nagineni, C. N. (1989) Biochem. Biophys. Res. Commun. 158, 319-325
7. Srinivasan, A. N., Nagineni, C. N., and Bhat, S. P. (1992) J. Biol. Chem. 267, 23337-23341
8. Bindels, J. G., Bessems, G. J., de Man, B. M., and Hoenders, H. J. (1983) Comp. Biochem. Physiol. B 76, 47-55
9. Augusteyn, R. C. (1998) Exp. Eye Res. 66, 669-674
10. Ingolia, T. D., and Craig, E. A. (1982) Proc. Natl. Acad. Sci. U. S. A. 79, 2360-2364
11. Klemenz, R., Andres, A. C., Frohli, E., Schafer, R., and Aoyama, A. (1993) J. Cell Biol. 120, 639-645
12. de Jong, W. W., Hendriks, W., Mulders, J. W., and Bloemendal, H. (1989) Trends Biochem. Sci. 14, 365-368
13. Wistow, G. (1985) FEBS Lett. 181, 1-6
14. Merck, K. B., Groenen, P. J., Voorter, C. E., de Haard-Hoekman, W. A., Horwitz, J., Bloemendal, H., and de Jong, W. W. (1993) J. Biol. Chem. 268, 1046-1052
15. Horwitz, J. (1992) Proc. Natl. Acad. Sci. U. S. A. 89, 10449-10453
16. Jakob, U., Gaestel, M., Engel, K., and Buchner, J. (1993) J. Biol. Chem. 268, 1517-1520
17. de Jong, W. W., Mulders, J. W., Voorter, C. E., Berbers, G. A., Hoekman, W. A., and Bloemendal, H. (1988) Adv. Exp. Med. Biol. 231, 95-108
18. Smith, J. B., Sun, Y., Smith, D. L., and Green, B. (1992) Protein Sci. 1, 601-608
19. Chiesa, R., Gawinowicz-Kolks, M. A., Kleiman, N. J., and Spector, A. (1987) Biochem. Biophys. Res. Commun. 144, 1340-1347
20. Dasgupta, S., Hohman, T. C., and Carper, D. (1992) Exp. Eye Res. 54, 461-470
21. Aoyama, A., Frohli, E., Schafer, R., and Klemenz, R. (1993) Mol. Cell. Biol. 13, 1824-1835
22. Klemenz, R., Scheier, B., Muller, A., Steiger, R., and Aoyama, A. (1994) Verh. Dtsch. Ges. Pathol. 78, 34-35
23. Kato, K., Ito, H., and Okamoto, K. (1997) Cell Stress Chaperones 2, 199-209
24. Roquemore, E. P., Dell, A., Morris, H. R., Panico, M., Reason, A. J., Savoy, L. A., Wistow, G. J., Zigler, J. S., Jr., Earles, B. J., and Hart, G. W. (1992) J. Biol. Chem. 267, 555-563
25. Lin, P., Smith, D. L., and Smith, J. B. (1997) Exp. Eye Res. 65, 673-680
26. Garland, D. L., Duglas-Tabor, Y., Jimenez-Asensio, J., Datiles, M. B., and Magno, B. (1996) Exp. Eye Res. 62, 285-291
27. O'Farrell, P. H. (1975) J. Biol. Chem. 250, 4007-4021
28. Anderson, E. I., and Spector, A. (1978) Exp. Eye Res. 26, 407-417
29. Stone, K. L., and Williams, K. R. (1993) in A Practical Guide to Protein and Peptide Purification and Microsequencing (Matsudaira, P., ed) 2nd Ed., pp. 45-69, Academic Press, San Diego
30. Farahbakhsh, Z. T., Huang, Q. L., Ding, L. L., Altenbach, C., Steinhoff, H. J., Horwitz, J., and Hubbell, W. L. (1995) Biochemistry 34, 509-516
31. Carver, J. A., and Lindner, R. A. (1998) Int. J. Biol. Macromol. 22, 197-209
32. Plater, M. L., Goode, D., and Crabbe, M. J. C. (1996) J. Biol. Chem. 271, 28558-28566
33. Smulders, R. H. P., Carver, J. A., Lindner, R. A., van Boekel, M. A. M., Bloemendal, H., and de Jong, W. W. (1996) J. Biol. Chem. 271, 29060-29066
34. Takemoto, L. (1994) Exp. Eye Res. 59, 239-242
35. Andley, U. P., Mathur, S., Griest, T. A., and Petrash, J. M. (1996) J. Biol. Chem. 271, 31973-31980
36. Smith, J. B., Shun-Shin, G. A., Sun, Y., Miesbauer, L. R., Yang, Z., Zhou, X., Schwedler, J., and Smith, D. L. (1995) J. Protein Chem. 14, 179-188
37. Smith, J. B., Sun, Y., Smith, D. L., and Green, B. (1992) Protein Sci. 1, 601-608
38. He, S., Pan, S., Wu, K., Amster, I. J., and Orlando, R. (1995) J. Mass Spectrom. 30, 424-431
39. Barret, A. J., Rawlings, N. D., and Woessner, J. F. (eds) (1998) Handbook of Proteolytic Enzymes, pp. 1341-1349, Academic Press, San Diego
40. Swanson, A. A., Davis, R. M., and Meinhardt, N. C. (1985) Curr. Eye Res. 4, 43-48
41. Gorthy, W. C., Steward, D. E., and McDonald, J. K. (1992) Curr. Eye Res. 11, 531-542
42. Sharma, K. K., and Ortwerth, B. J. (1992) Exp. Eye Res. 54, 1005-1010
43. Kato, K., Goto, S., Hasegawa, K., and Inaguma, Y. (1993) J. Biochem. (Tokyo) 114, 640-647
44. Klemenz, R., Scheier, B., Muller, A., Steiger, R., and Aoyama, A. (1994) Verh. Dtsch. Ges. Pathol. 78, 34-35
45. Ito, H., Okamoto, K., Nakayama, H., Isobe, T., and Kato, K. (1997) J. Biol. Chem. 272, 29934-29941
46. Chiesa, R., Gawinowicz-Kolks, M. A., and Spector, A. (1987) J. Biol. Chem. 262, 1438-1441
47. Spector, A., Chiesa, R., Sredy, J., and Garner, W. (1985) Proc. Natl. Acad. Sci. U. S. A. 82, 4712-4716
48. Voorter, C. E., de Haard-Hoekman, W. A., Roersma, E. S., Meyer, H. E., Bloemendal, H., and de Jong, W. W. (1989) FEBS Lett. 259, 50-52
49. Iwaki, T., Iwaki, A., and Goldman, J. E. (1993) Acta Neuropathol. 85, 475-480
50. Iwaki, T., Iwaki, A., Tateishi, J., Sakaki, Y., and Goldman, J. E. (1993) Am. J. Pathol. 143, 487-495
51. Iwaki, T., Kume-Iwaki, A., Liem, R. K., and Goldman, J. E. (1989) Cell 57, 71-78
52. Nicholl, I. D., and Quinlan, R. A. (1994) EMBO J. 13, 945-953
53. Wang, K., and Spector, A. (1996) Eur. J. Biochem. 242, 56-66
54. Carter, J. M., Hutcheson, A. M., and Quinlan, R. A. (1995) Exp. Eye Res. 60, 181-192
55. Del Vecchio, P. J., MacElroy, K. S., Rosser, M. P., and Church, R. L. (1984) Curr. Eye Res. 3, 1213-1219
56. Gopalakrishnan, S., and Takemoto, L. (1992) Curr. Eye Res. 11, 929-933
57. Bhat, S. P., Hale, I. L., Matsumoto, B., and Elghanayan, D. (1999) Eur. J. Cell Biol. 78, 143-150
58. Groenen, P. J., Smulders, R. H., Peters, R. F., Grootjans, J. J., van den Ijssel, P. R., Bloemendal, H., and deJong, W. W. (1994) Eur. J. Biochem. 220, 795-799
59. Lorand, L., Velasco, P. T., Murthy, S. N., Wilson, J., and Parameswaran, K. N. (1992) Proc. Natl. Acad. Sci. U. S. A. 89, 11161-11163
60. Emmons, T., and Takemoto, L. (1992) Exp. Eye Res. 55, 551-554