4,10-Dihydro-5H-thieno[3,2-c][1]benzazepine derivatives and 9,10- dihydro-4H-thieno[2,3-c][1]benzazepine derivatives as orally active arginine vasopressin receptor antagonists

Bioorganic and Medicinal Chemistry Letters

Volumn 9, Issue 13, 1999, Pages 1733-1736

  Aranapakam, Venkatesan ^a   Albright, J Donald ^a   Grosu, George T ^a   Chan, Peter S ^a   Coupet, Joseph ^a   Saunders, Trina ^a   Ru, Xun ^a   Mazandarani, H ^a  

^a PFIZER INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4,10 DIHYDRO 5H THIENO[3,2 C][1]BENZAZEPINE; 9,10 DIHYDRO 4H THIENO[2,3 C][1]BENZAZEPINE; ARGIPRESSIN RECEPTOR; LIXIVAPTAN; UNCLASSIFIED DRUG; VASOPRESSIN RECEPTOR ANTAGONIST;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; DRUG ACTIVITY; DRUG POTENCY; DRUG RECEPTOR BINDING; DRUG STRUCTURE; DRUG SYNTHESIS; NONHUMAN; ORAL DRUG ADMINISTRATION; RAT; REACTION ANALYSIS; STRUCTURE ACTIVITY RELATION;

ADMINISTRATION, ORAL; ANIMALS; AZEPINES; BENZAMIDES; BENZAZEPINES; FIBROBLASTS; INHIBITORY CONCENTRATION 50; MICE; RECEPTORS, VASOPRESSIN; STRUCTURE-ACTIVITY RELATIONSHIP; THIOPHENES;

EID: 0033526881     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(99)00278-4     Document Type: Article

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