Prevention of infection of influenza virus in DQ6 mice, a human model, by a peptide vaccine prepared according to the cassette theory

Vaccine

Volumn 17, Issue 9-10, 1999, Pages 1161-1168

  Matsuki, Naoto ^a   Ogasawara, Kazumasa ^a   Takami, Kimitaka ^a   Namba, Kenichi ^a   Takahashi, Akio ^a   Fukui, Yoshinori ^b   Sasazuki, Takehiko ^b   Iwabuchi, Kazuya ^a   Good, Robert A ^c   Onoé, Kazunori ^a  

^a Inst Immunological Sci   (Japan)

^b KYUSHU UNIVERSITY   (Japan)

^c UNIVERSITY OF SOUTH FLORIDA   (United States)

Author keywords

Influenza virus; MHC; Peptide vaccine

Indexed keywords

HLA DQ ANTIGEN; HYBRID PROTEIN; INFLUENZA VACCINE; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; NEUTRALIZING ANTIBODY;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBODY SPECIFICITY; ARTICLE; CELL PROLIFERATION; COMPLEX FORMATION; CONTROLLED STUDY; DRUG EFFECT; GROWTH INHIBITION; HELPER CELL; IMMUNOGENICITY; INFLUENZA VIRUS; MAJOR HISTOCOMPATIBILITY COMPLEX; MOUSE; NONHUMAN; PEPTIDE SYNTHESIS; PRIORITY JOURNAL; RECEPTOR BINDING; VIRUS INFECTION;

AMINO ACID SEQUENCE; ANIMALS; ENZYME-LINKED IMMUNOSORBENT ASSAY; GENES, MHC CLASS II; HISTOCOMPATIBILITY ANTIGENS CLASS II; HLA-DQ ANTIGENS; HUMANS; INFLUENZA A VIRUS; INFLUENZA VACCINES; INFLUENZA, HUMAN; MICE; MICE, MUTANT STRAINS; MOLECULAR SEQUENCE DATA; PEPTIDES; T-LYMPHOCYTES; VACCINES, SYNTHETIC;

EID: 0033525772     PISSN: 0264410X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0264-410X(98)00336-3     Document Type: Article

References (36)

1. Schwartz R.H. T-lymphocyte recognition of antigen in association with gene products of the major histocompatibility complex. Annu Rev Immunol. 3:1985;237-261.
2. Davis M.M., Bjorkman P.J. T-cell antigen receptor genes and T-cell recognition. Nature. 334:1988;395-402.
3. Garboczi D., Ghosh P., Utz U., Fan Q., Biddison W., Wiley D. Structure of the complex between human T-cell receptor, viral peptide and HLA-A2. Nature. 384:1996;134-141.
4. Garcia K.C., Degano M., Stanfield R.L., Brunmark A., Jackson M.R., Peterson P.A., Teyton L., Wilson I.A. An αβ T cell receptor structure at 2.5 Å and its orientation in the TCR-MHC complex. Science. 274:1996;209-219.
5. Ogasawara K., Naruse H., Itoh Y., Gotohda T., Arikawa J., Kida H., Good R.A., Onoé K. A strategy for making synthetic peptide vaccines. Proc Natl Acad Sci USA. 89:1992;8995-8999.
6. Ogasawara K., Onoé K. MHC binding motifs and design of peptide-based vaccines. Trends Microbiol. 1:1993;276-279.
7. Naruse H., Ogasawara K., Kaneda R., Hatakeyama S., Itoh T., Kida H., Miyazaki T., Good R.A., Onoé K. A potential peptide vaccine against two different strains of influenza virus isolated at intervals of about 10 years. Proc Natl Acad Sci USA. 91:1994;9588-9592.
8. Francis M.J., Hastings G.Z., Syred A.D., McGinn B., Brown F., Rowlands D.J. Nonresponsiveness to a foot-and-mouth disease virus peptide overcome by addition of foreign helper T-cell determinants. Nature. 300:1987;168-170.
9. Leonetti M., Pillet L., Maillere B., Lamthanh H., Frachon P., Couderc J., Menez A. Immunization with a peptide having both T cell and conformationally restricted B cell epitopes elicits neutralizing antisera against a snake neurotoxin. J Immunol. 145:1990;4214-4221.
10. Chai S.K., Clavijo P., Tam J.P., Zavala F. Immunogenic properties of multiple antigen peptide systems containing defined T and B epitopes. J Immunol. 149:1992;2385-2390.
11. Hammer J., Valsasnini P., Tolba K., Bolin D., Higelin J., Takacs B., Sinigaglia F. Promiscuous and allele-specific anchors in HLA-DR-binding peptides. Cell. 74:1993;197-203.
12. Chicz R.M., Urban R.G., Gorga J.C., Vignali D.A., Lane W.S., Strominger J.L. Specificity and promiscuity among naturally processed peptides bound to HLA-DR alleles. J Exp Med. 178:1993;27-47.
13. Panina-Bordignon P., Tan A., Termijtelen A., Demotz S., Corradin G., Lanzavecchia A. Universally immunogenic T cell epitopes: promiscuous binding to human MHC class II and promiscuous recognition by T cells. Eur J Immunol. 19:1989;2237-2242.
14. Alexander J., Sidney J., Southwood S., Ruppert J.C., Oseroff C., Maewal A., Snoke K., Serra H.M., Kubo R.T., Sette A., Grey H.M. Development of high potency universal DR-restricted helper epitopes by modification of high affinity DR-blocking peptides. Immunity. 1:1994;751-761.
15. * 0201) molecule. Eur J Immunol. 26:1996;2764-2772.
16. Johansen B.H., Vartdal F., Eriksen J.A., Thorsby E., Sollid L.M. Identification of a putative motif for binding of peptides to HLA-DQ2. Int Immunol. 8:1996;177-182.
17. Matsushita S., Nishi T., Oiso M., Yamaoka K., Yone K., Kanai T., Nishimura Y. HLA-DQ-binding peptide motifs. 1. Comparative binding analysis of type II collagen-derived peptides to DR and DQ molecules of rheumatoid arthritis-susceptible and nonsusceptible haplotypes. Int Immunol. 8:1996;757-764.
18. Godkin A.J., Davenport M.P., Willis A., Jewell D.P., Hill A.V. Use of complete eluted peptide sequence data from HLA-DR and -DQ molecules to predict T cell epitopes and the influence of the nonbinding terminal regions of ligands in epitope selection. J Immunol. 161:1998;850-858.
19. Hammer J., Belunis C., Bolin D., Papadopoulos J., Walsky R., Higelin J., Danho W., Sinigaglia F., Nagy Z.A. High-affinity binding of short peptides to major histocompatibility complex class II molecules by anchor combinations. Proc Natl Acad Sci USA. 91:1994;4456-4460.
20. Brown J.H., Jardetzky T.S., Gorga J.C., Stern L.J., Urban R.G., Strominger J.L., Wiley D.C. Three-dimensional structure of the human class II histocompatibility antigen HLA-DR1. Nature. 364:1993;33-39.
21. Sinigaglia F., Hammer J. Motifs and supermotifs for MHC class II binding peptides. J Exp Med. 181:1995;449-451.
22. Jardetzky T.S., Gorga J.C., Busch R., Rothbard J.B., Strominger J.L., Wiley D.C. Peptide binding to HLA-DR1: a peptide with most residues substituted to alanine retains MHC binding. EMBO J. 9:1990;1797-1803.
23. Hill C.M., Hayball J.D., Allison A.A., Rothbard J.B. Conformational and structural characteristics of peptides binding to HLA-DR molecules. J Immunol. 147:1991;189-197.
24. O'Sullivan D., Arrhenius T., Sidney J., Del Guercio M.F., Albertson M., Wall M., Oseroff C., Southwood S., Colon S.M., Gaeta F.C.A., Sette A. On the interaction of promiscuous antigenic peptides with different DR alleles. Identification of common structural motifs. J Immunol. 147:1991;2663-2669.
25. Yamamoto K., Fukui Y., Esaki Y., Inamitsu T., Sudo T., Yamane K., Kamikawaji N., Kimura A., Sasazuki T. Functional interaction between human histocompatibility leukocyte antigen (HLA) class II and mouse CD4 molecule in antigen recognition by T cells in HLA-DR and DQ transgenic mice. J Exp Med. 180:1994;165-171.
26. Cosgrove D., Gray D., Dierich A., Kaufman J., Lemeur M., Benoist C., Mathis D. Mice lacking MHC class II molecules. Cell. 66:1991;1051-1066.
27. Takahashi A., Ogasawara K.N., Matsuki N., Fujinaga K., Nakaya T., Ikuta K., Auwanit W., Honda M., Fukui Y., Sasazuki T., Iwabuchi K., Onoé K. Development of peptide vaccines inducing production of neutralizing antibodies against HIV-1 viruses in HLA-DQ6 mice. Vaccine. 16:1998;1537-1543.
28. Ogasawara K., Wambua P.P., Gotohda T., Onoé K. Modification of the T cell responsiveness to synthetic peptides by substituting amino acids on agretopes. Int Immunol. 2:1990;219-224.
29. Ogasawara K., Maloy W.L., Beverly B., Schwartz R.H. Functional analysis of the antigenic structure of a minor T cell determinant from pigeon cytochrome c: evidence against an α-helical conformation. J Immunol. 142:1989;1448-1456.
30. Itoh Y., Ogasawara K., Takami K., Gotohda T., Naruse H., Good R.A., Onoé K. Determination of amino acids on agretopes of pigeon cytochrome c related peptides specifically bound to I-A allelic products. Eur J Immunol. 24:1994;76-83.
31. Naruse H., Ogasawara K., Takami K., Kajino K., Gotohda T., Itoh Y., Miyazaki T., Good R.A., Onoé K. Analysis of epitopic residues introduced into the hybrid peptide vaccines prepared according to the cassette theory. Vaccine. 12:1994;776-782.
32. b molecule. Proc Natl Acad Sci USA. 94:1997;12047-12052.
33. Stern L.J., Brown J.H., Jardetzky T.S., Gorga J.C., Urban R.G., Strominger J.L., Wiley D.C. Crystal structure of the human class II MHC protein HLA-DR1 complexed with an influenza virus peptide. Nature. 368:1994;215-221.
34. Fremont D.H., Hendrickson W.A., Marrack P., Kappler J. Structures of an MHC class II molecule with covalently bound single peptides. Science. 272:1996;1001-1004.
35. k in complex with a dominant epitope of lysozyme. Immunity. 8:1998;305-317.
36. d-peptide complexes reveal that high affinity can be achieved without large anchor residues. Immunity. 8:1998;319-329.