Abnormal distribution of hippocampal mossy fibers in rats exposed to X- irradiation in utero

Developmental Brain Research

Volumn 112, Issue 2, 1999, Pages 275-280

  Miki, Takanori ^a   Sawada, Kazuhiko ^b   Sun, Xue Zhi ^b   Hisano, Setsuji ^b   Takeuchi, Yoshiki ^a   Fukui, Yoshihiro ^b  

^a KAGAWA UNIVERSITY   (Japan)

^b UNIVERSITY OF TOKUSHIMA   (Japan)

Author keywords

Hippocampus; In utero; Laminar structure; Mossy fiber; X irradiation

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN DEVELOPMENT; CONTROLLED STUDY; DOSE RESPONSE; HIPPOCAMPUS; HISTOPATHOLOGY; IONIZING RADIATION; MALE; MOSSY FIBER; NERVE FIBER GROWTH; NONHUMAN; PRENATAL EXPOSURE; PRIORITY JOURNAL; PYRAMIDAL NERVE CELL; RADIATION DOSE; RADIOSENSITIVITY; RAT; TERATOGENESIS; X IRRADIATION;

ANIMALS; ANIMALS, NEWBORN; DOSE-RESPONSE RELATIONSHIP, RADIATION; FEMALE; FETUS; MALE; MOSSY FIBERS, HIPPOCAMPAL; PREGNANCY; PRENATAL EXPOSURE DELAYED EFFECTS; RATS; REFERENCE VALUES; WHOLE-BODY IRRADIATION;

ANIMALIA; HIPPOCAMPUS HIPPOCAMPUS;

EID: 0033524760     PISSN: 01653806     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0165-3806(98)00177-1     Document Type: Article

References (20)

1. 3H -thymidine autoradiography J. Comp. Neurol. 109:1980;87-114.
2. S.A. Bayer, J. Altman, Neurogenesis and neuronal migration, in: G. Paxinos (Ed.), The Rat Nervous System, Academic Press, Australia, 1995, pp. 1041-1078.
3. Danscher G. Histochemical demonstration of heavy metals. A revised version of the sulphide silver method suitable for both light and electronmicroscopy. Histochemistry. 71:1981;1-16.
4. Fukui Y., Hoshino K., Hayasaka I., Inouye M., Kameyama Y. Developmental disturbance of rat cerebral cortex following prenatal low-dose X-irradiation: a quantitative study. Exp. Neurol. 112:1991;292-298.
5. Hoshino K., Kameyama Y. Developmental-stage-dependent radiosensitivity of neural cells in the ventricular zone of telencephalon in mouse and rat fetuses. Teratology. 37:1988;257-262.
6. Jensh R.P., Eisenman L.M., Brent R.L. Postnatal neurophysiologic effects of prenatal X-irradiation. Int. J. Radiat. Biol. 67:1995;217-227.
7. Y. Kameyama, K. Hoshino, Sensitive phases of CNS development, in: H. Kriegel, W. Schmahl, G.B. Gebert, F.E. Stieve (Eds.), Radiation Risks to the Developing Nervous System, Gustav Fischer Verlag, Stuttgart, 1986, pp. 75-92.
8. Laurberg S., Zimmer J. Lesion-induced rerouting of hippocampal mossy fibers in developing but not in adult rats. J. Comp. Neurol. 190:1980;627-650.
9. Miki T., Fukui Y., Takeuchi Y., Itoh M. A quantitative study of the effects of prenatal X-irradiation on the development of cerebral cortex in rats. Neurosci. Res. 23:1995;241-247.
10. Otake M., Schull W.J. In utero exposure to A-bomb radiation: a reassessment. Br. J. Radiol. 57:1984;409-414.
11. Ramachandran Y.S., Clarke P.G.H., Whitteridge D. Early hypothyroidism alters the distribution of mossy fibers in the rat hippocampus. Nature. 268:1977;335-337.
12. Rodier P.M. Chronology of neuron development: animal studies and their clinical implications. Dev. Med. Child Neurol. 22:1980;525-545.
13. Rolls E. A theory of hippocampal function in memory. Hippocampus. 6:1996;601-620.
14. Schlessinger A.R., Cowan W.M., Swanson L.W. The time of origin of neurons in Ammon's horn and the associated retrohippocampal fields. Anat. Embryol. 154:1978;153-173.
15. Seo M., Inouye M., Kiyono S., Shibagaki M. Effects of environmentally differential rearing upon maze performance in prenatally irradiated microcephalic rats. Teratology. 26:1982;221-227.
16. Singh S.C. Deformed dendrites and reduced spine numbers on ectopic neurons in the hippocampus of rats exposed to methylazoxymethanol acetate. Acta Neuropathol. 49:1980;192-198.
17. Steckler T., Drinkenburg W.H.I.M., Sahgal A., Aggleton J.P. Recognition memory in rats: II. Neuroanatomical substrates. Prog. Neurobiol. 54:1988;313-332.
18. Tamaki Y., Hoshino K., Kameyama Y. Avoidance learning deficits in prenatally gamma-irradiated rats. Cong. Anom. 29:1989;295-308.
19. Tamaki Y., Inouye M. Brightness discrimination learning in a skinner box in prenatally X-irradiated rats. Physiol. Behav. 16:1976;343-348.
20. West J.R., Hodges C.A., Black A.C. Jr. Prenatal exposure to ethanol alters the organization of hippocampal mossy fibers in rats. Science. 211:1981;957-959.