Radical cyclizations. A convergent total synthesis of (±)-γ-Lycorane

Tetrahedron Letters

Volumn 40, Issue 6, 1999, Pages 1125-1128

  Cossy, Janine ^a   Tresnard, Ludovic ^a   Gomez Pardo, Domingo ^a  

^a CNRS   (France)

Author keywords

Alkaloids; Dehalogenation; Halogenation; Radical reactions

Indexed keywords

ALCOHOL; ALKALOID; GAMMA LYCORANE; UNCLASSIFIED DRUG;

AMINATION; ANTINEOPLASTIC ACTIVITY; ANTIVIRAL ACTIVITY; ARTICLE; CHEMICAL REACTION; CHLORINATION; CYCLIZATION; DEHALOGENATION; GROWTH INHIBITION; HALOGENATION; PLANT GROWTH; PROTEIN SYNTHESIS; SYNTHESIS;

EID: 0033524684     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0040-4039(98)02585-4     Document Type: Article

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26. 6) δ : 7.19 (s, 1H), 7.05 (s, 1H), 5.21 (s, 2H), 4.00-3.93 (m, 1H), 3.67 (d, J = 14.2 Hz, 1H), 3.40 (d, J = 14.2 Hz, 1H), 2.94-2.83 (m, 1H), 2.76-2.71 (m, 1H), 2.19-2.06 (m, 1H), 2.03 (td, J = 5.1 and 9.9 Hz, 1H), 1.90-1.80 (m, 1H), 1.79-0.80 (m, 7H).
27. 6) δ : 7.40 (s, 1H), 7.21 (s, 1H), 5.23 (d, J = 1.5 Hz, 1H), 5.20 (d, J = 1.5 Hz, 1H), 4.57 (d, J = 15.2 Hz, 1H), 3.83 (td, J = 3.4 and 10.4 Hz, 1H), 3.69 (d, J = 15.2 Hz, 1H), 3.09-2.99 (m, 1H), 2.77 (dd, J = 3.8 and 5.2 Hz, 1H), 2.24 (td, J = 4.0 and 8.8 Hz, 1H), 1.99-1.86 (m, 1H), 1.79-0.80 (m, 8H).
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