Synthesis and biological evaluation of the first N-alkyl cage dimeric 4- aryl-1,4-dihydropyridines as novel nonpeptidic HIV-1 protease inhibitors

Journal of Medicinal Chemistry

Volumn 42, Issue 22, 1999, Pages 4729-4732

  Hilgeroth, Andreas ^a   Wiese, Michael ^a   Billich, Andreas ^b  

^a MARTIN LUTHER UNIVERSITY HALLE WITTENBERG   (Germany)

^b Novartis Forschungsinstitut GmbH   (Austria)

Author keywords

[No Author keywords available]

Indexed keywords

1,4 DIHYDROPYRIDINE DERIVATIVE; 3,9 DIBENZYL 1,5,7,11 TETRAHYDROXYMETHYL 6,12 DIPHENYL 3,9 DIAZAHEXACYCLO[6.4.0.0 2.7.0 4.11.0 5.10] DODECANE; 4,7 DIBENZYL 2,3,4,5,6,7 HEXAHYDRO 5,6 DIHYDROXY 1,3 BIS[4 (HYDROXYMETHYL)BENZYL] 2H 1,3 DIAZEPIN 2 ONE; A 98881; ANTIINFECTIVE AGENT; MOZENAVIR; PROTEINASE INHIBITOR; UNCLASSIFIED DRUG; UREA DERIVATIVE;

ARTICLE; CONTROLLED STUDY; DRUG STRUCTURE; DRUG SYNTHESIS; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; IN VITRO STUDY; NONHUMAN; PROTEINASE INHIBITION; STRUCTURE ACTIVITY RELATION;

EID: 0033524021     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm991115k     Document Type: Article

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