No pathogenic mutations in the persyn gene in Parkinson's disease

Neuroscience Letters

Volumn 259, Issue 1, 1999, Pages 65-66

  Lincoln, Sarah ^a   Gwinn Hardy, Katrina ^a   Goudreau, John ^a   Christine Chartier Harlin, Marie ^b,c   Baker, Matt ^a   Mouroux, Vincent ^b   Richard, Florence ^b   Destée, Alain ^c   Becquet, Estelle ^c   Amouyel, Philippe ^c   Lynch, Tim ^d   Hardy, John ^a   Farrer, Matt ^a  

^a MAYO CLINIC   (United States)

^b INSTITUT PASTEUR DE LILLE   (France)

^c LILLE UNIVERSITY HOSPITAL   (France)

^d MATER MISERICORDIAE UNIVERSITY HOSPITAL   (Ireland)

Author keywords

Synuclein; Genetics; Parkinson's disease; Persyn

Indexed keywords

ARTICLE; GENE MUTATION; GENE SEQUENCE; HUMAN; PARKINSON DISEASE; PRIORITY JOURNAL; SEQUENCE ANALYSIS;

AGE OF ONSET; AGED; GAMMA-SYNUCLEIN; HUMANS; MIDDLE AGED; MUTATION; NEOPLASM PROTEINS; NERVE TISSUE PROTEINS; PARKINSON DISEASE; SEQUENCE ANALYSIS, DNA;

EID: 0033521656     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3940(98)00901-X     Document Type: Article

References (11)

1. Buchman V.L., Adu J., Pinon L.G., Ninkina N.N., Davies A.N. Persyn, a member of the synuclein family influences neurofilament network integrity. Nat. Neurosci. 1:1998;101-102.
2. Buchman, V.L., Hunter, H.J.A., Pinon, L.G., Thompson, J., Privalova, E.M., Ninkina, N.N. and Davies, A.N., Persyn, a member of the synuclein family has a distinct pattern of expression in the developing nervous system, J. Neurosci., (1998) in press.
3. Gelb, D.J., Oliver, E. and Gilman, S., Diagnostic criteria for Parkinson's disease, Arch. Neurol., (1998) in press.
4. Goldman J.E., Yen S.H., Chiu F.C., Peress N.S. Lewy bodies of Parkinson's disease contain neurofilament antigens. Science. 221:1983;1082-1084.
5. Farrer M., Wavrant-De Vrieze F., Crook R., Boles L., Perez-Tur J., Hardy J., Johnson W.G., Steele J., Maraganore D., Gwinn K., Lynch T. Low frequency of alpha-synuclein mutations in familial Parkinson's disease. Ann. Neurol. 43:1998;394-397.
6. Jakes R., Spillantini M.G., Goedert M. Identification of two distinct synucleins from human brain. FEBS Lett. 345:1994;27-32.
7. Kruger R., Kuhn W., Muller T., Woitalla D., Graeber M., Kosel S., Przuntek H., Epplen J.T., Schols L., Riess O. Ala30Pro mutation in the gene encoding [alpha]-synuclein in Parkinson's disease. Nat. Genet. 18:1998;106-110.
8. Maroteaux L., Scheller R.H. The rat brain synucleins; family of proteins transiently associated with neuronal membrane. Mol. Brain Res. 11:1991;335-343.
9. Ninkina N.N., Alimova-Kost M.V., Paterson J.W.E., Delaney L., Cohen B.B., Imreh S., Gnuchev N.V., Davies A.M., Buchman V.L. Organization, expression and polymorphism of the human persyn gene. Hum. Mol. Genet. 7:1998;1417-1424.
10. Polymeropoulos M.H., Lavedan C., Leroy E., Ide S.E., Dehejia A., Dutra A., Pike B., Root H., Rubenstein J., Boyer R., Stenroos E.S., Chandrasekharappa S., Athanassiadou A., Papapetropoulos T., Johnson W.G., Lazzarini A.M., Duvoisin R.C., Di Iorio G., Golbe L.I., Nussbaum R.L. Mutation in the [alpha]-synuclein gene identified in families with Parkinson's disease. Science. 276:1997;2045-2047.
11. Uéda K., Fukushima H., Masliah E., Xia Y., Iwai A., Yoshimoto M., Otero D.A.C., Kondo J., Ihara Y., Saitoh T. Molecular cloning of cDNA encoding an unrecognized component of amyloid in Alzheimer disease, Proc. Natl. Acad. Sci. USA. 90:1993;11282-11286.