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During the Wittig reaction, significant amounts of the β-elimination product were formed. Thus, the reaction was terminated before completion
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During the Wittig reaction, significant amounts of the β-elimination product were formed. Thus, the reaction was terminated before completion.
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Predominance of mismatched pairs in crotylboration with Roush's reagent have been reported. See: (a) Niel, G.; Roux, F.; Maisonnasse, Y.; Maugras, I.; Poncet, J.; Jouin, P. J. Chem. Soc., Perkin Trans, 1 1994, 1275-1280; (b) Zheng, W.; DeMattei, J. A.; Wu, J.-P.; Duan, J. J.-W.; Cook, L. R.; Oinuma, H.; Kishi, Y. J. Am. Chem. Soc. 1996, 118, 7946-7968.
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Predominance of mismatched pairs in crotylboration with Roush's reagent have been reported. See:(a) Niel, G.; Roux, F.; Maisonnasse, Y.; Maugras, I.; Poncet, J.; Jouin, P. J. Chem. Soc., Perkin Trans, 1 1994, 1275-1280; (b) Zheng, W.; DeMattei, J. A.; Wu, J.-P.; Duan, J. J.-W.; Cook, L. R.; Oinuma, H.; Kishi, Y. J. Am. Chem. Soc. 1996, 118, 7946-7968.
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0009621051
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note
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2O, THF, -78°C, 75%. (matrix presented).
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