Amino acid substitutions at positions 207 and 221 contribute to catalytic differences between murine glutathione S-transferase A1-1 and A2-2 toward (+)-anti-7,8-dihydroxy-9,10-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene

Biochemistry

Volumn 38, Issue 31, 1999, Pages 9824-9830

  Xia, Hong ^a   Gu, Yijun ^a,b   Pan, Su Shu ^c   Ji, Xinhua ^b   Singh, Shivendra V ^a  

^a MERCY HOSPITAL OF PITTSBURGH   (United States)

^b NATIONAL CANCER INSTITUTE   (United States)

^c UNIVERSITY OF PITTSBURGH CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GLUTATHIONE TRANSFERASE; ISOLEUCINE; METHIONINE; PYRENE DERIVATIVE;

AMINO ACID SUBSTITUTION; AMINO TERMINAL SEQUENCE; ARTICLE; CONFORMATIONAL TRANSITION; CRYSTAL STRUCTURE; ENZYME ACTIVITY; ENZYME MECHANISM; ENZYME SPECIFICITY; ENZYME SUBUNIT; MOLECULAR MODEL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN INTERACTION;

AMINO ACID SUBSTITUTION; ANIMALS; BENZOPYRENES; CATALYSIS; ENZYME ACTIVATION; FEMALE; GLUTATHIONE TRANSFERASE; HUMANS; ISOENZYMES; KINETICS; MICE; MICE, INBRED A; MODELS, MOLECULAR; MUTAGENESIS, SITE-DIRECTED; RECOMBINANT PROTEINS; STEREOISOMERISM;

MURINAE;

EID: 0033520072     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi9908078     Document Type: Article

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