CTLA-4-Fc treatment of ongoing EAE improves recovery, but has no effect upon relapse rate. Implications for the mechanisms involved in disease perpetuation

Journal of Neuroimmunology

Volumn 96, Issue 2, 1999, Pages 144-147

  Cross, Anne H ^a   San, Manuel ^a   Keeling, Richard M ^a   Karr, Robert W ^b  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b PFIZER INC   (United States)

Author keywords

CTLA 4 Ig; Experimental autoimmune encephalomyelitis; Multiple sclerosis; T cell co stimulation

Indexed keywords

B7 ANTIGEN; CD86 ANTIGEN; CYTOTOXIC T LYMPHOCYTE ANTIGEN 4; FC RECEPTOR; HYBRID PROTEIN; IMMUNOGLOBULIN; PLACEBO;

ALLERGIC ENCEPHALOMYELITIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; AUTOIMMUNE DISEASE; CONTROLLED STUDY; FEMALE; IMMUNOPHARMACOLOGY; MOUSE; MULTIPLE SCLEROSIS; NONHUMAN; PRIORITY JOURNAL; RELAPSE; T LYMPHOCYTE ACTIVATION;

ANIMALS; ANTIGENS, CD; ANTIGENS, DIFFERENTIATION; ENCEPHALOMYELITIS, AUTOIMMUNE, EXPERIMENTAL; FEMALE; IMMUNOCONJUGATES; IMMUNOGLOBULIN G; IMMUNOSUPPRESSIVE AGENTS; MICE; MICE, INBRED STRAINS; RECURRENCE; REMISSION INDUCTION;

EID: 0033519282     PISSN: 01655728     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0165-5728(99)00015-6     Document Type: Article

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