Nonpeptidic HIV protease inhibitors: 6-alkyl-5,6-dihydropyran-2ones possessing a novel and achiral 3-(2-t-butyl-5-methyl-4-sulfamate)phenylthio moiety

Bioorganic and Medicinal Chemistry Letters

Volumn 9, Issue 15, 1999, Pages 2217-2222

  Vara Prasad, J V N ^a   Markoski, Larry J ^a   Boyer, Fred E ^a   Domagala, John M ^a   Ellsworth, Edmund L ^a   Gajda, Christopher ^a   Hagen, Susan E ^a   Tait, Bradley D ^a   Lunney, Elizabeth A ^a   Tummino, Peter J ^a   Ferguson, Donna ^a   Holler, Tod ^a   Hupe, Donald ^a   Nouhan, Carolyn ^a   Gracheck, Stephen J ^a   VanderRoest, Steven ^a   Saunders, James ^a   Iyer, K ^a   Sinz, M ^a  

^a PFIZER INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

5,6 DIHYDROPYRAN 2 ONE DERIVATIVE; PROTEINASE INHIBITOR; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANTIVIRAL ACTIVITY; ARTICLE; BINDING AFFINITY; CRYSTAL STRUCTURE; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME BINDING; HUMAN IMMUNODEFICIENCY VIRUS; MOUSE; NONHUMAN; REACTION ANALYSIS; VIRUS INHIBITION;

ANIMALIA; HUMAN IMMUNODEFICIENCY VIRUS; RNA VIRUSES;

EID: 0033517022     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(99)00360-1     Document Type: Article

References (10)

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