Facile stereoselective syntheses of (E)- and (Z)-α-substituted cinnamates by stereoselective dehydration reaction with 1-ethyl-3-(3- dimethylaminopropyl)carbodiimide (EDC)

Tetrahedron Letters

Volumn 40, Issue 27, 1999, Pages 5019-5022

  Hiroshi, Sai ^a   Ohmizu, Hiroshi ^a  

^a MITSUBISHI TANABE PHARMA CORPORATION   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

1 (3 DIMETHYLAMINOPROPYL) 3 ETHYLCARBODIIMIDE; CINNAMIC ACID DERIVATIVE; GAMMA BUTYROLACTONE;

ARTICLE; CHEMICAL REACTION; CONFORMATIONAL TRANSITION; DEHYDRATION; STEREOCHEMISTRY; STRUCTURE ANALYSIS; SYNTHESIS;

EID: 0033516718     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0040-4039(99)00923-5     Document Type: Article

References (12)

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2. 4
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11. 2 in toluene at 80 °C, and E-isomer was not obtained at all.
12. 1H-NMR, the product was purified by silica gel column chromatography.