Competitive, reversible inhibition of cytosolic phospholipase A2 at the lipid-water interface by choline derivatives that partially partition into the phospholipid bilayer

Journal of Biological Chemistry

Volumn 274, Issue 27, 1999, Pages 18864-18871

  Burke, James R ^a   Witmer, Mark R ^a   Zusi, F Christopher ^a   Gregor, Kurt R ^a   Davern, Lynda B ^a   Padmanabha, Ramesh ^a   Swann, R Thomas ^a   Smith, Daniel ^a   Tredup, Jeffrey A ^a   Micanovic, Radmila ^a   Manly, Susan P ^a   Villafranca, Joseph J ^a   Tramposch, Kenneth M ^a  

^a BRISTOL MYERS SQUIBB   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMMONIUM CHLORIDE; ARACHIDONIC ACID; CHOLINE DERIVATIVE; DIMYRISTOYLPHOSPHATIDYLCHOLINE; FORMYLMETHIONYLLEUCYLPHENYLALANINE; LIPID; PHOSPHOLIPASE A; PHOSPHOLIPID; WATER;

ARACHIDONIC ACID METABOLISM; ARTICLE; CATALYSIS; CELL MEMBRANE; COMPETITIVE INHIBITION; DIFFERENTIAL SCANNING CALORIMETRY; DOSE RESPONSE; ENZYME ACTIVITY; ENZYME ASSAY; ENZYME BINDING; HUMAN; HUMAN CELL; INHIBITION KINETICS; PRIORITY JOURNAL;

ARACHIDONIC ACID; CALORIMETRY, DIFFERENTIAL SCANNING; CHOLESTEROL; CHOLINE; HUMANS; INOSITOL 1,4,5-TRISPHOSPHATE; KINETICS; LASERS; LIPID BILAYERS; LIPIDS; N-FORMYLMETHIONINE LEUCYL-PHENYLALANINE; PHOSPHOLIPASES A; QUATERNARY AMMONIUM COMPOUNDS; SCATTERING, RADIATION; U937 CELLS; WATER;

EID: 0033516643     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.274.27.18864     Document Type: Article

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