Discovery of a regulatory motif that controls the exposure of specific upstream cyclin-dependent kinase sites that determine both conformation and growth suppressing activity of pRb

Journal of Biological Chemistry

Volumn 274, Issue 14, 1999, Pages 9463-9471

  Barbara, Driscoll ^a   T'Ang, Anne ^a   Hu, Yi Hui ^a   Yan, Chun Li ^a   Fu, Yue ^a   Luo, Yi ^a   Wu, Kai Jin ^a   Wen, Shumin ^a   Shi, Xiang He ^a   Barsky, Lora ^a   Weinberg, Kenneth ^a   Murphree, A Linn ^a   Fung, Yuen Kai ^a,b  

^a UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^b CHILDREN S HOSPITAL LOS ANGELES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIN DEPENDENT KINASE; SERINE; THREONINE; TRANSFORMING GROWTH FACTOR BETA;

ARTICLE; CANCER INHIBITION; CELL CYCLE; ENZYME REGULATION; ENZYME REPRESSION; GENE ACTIVITY; GENE CONTROL; GENE MUTATION; HUMAN; HUMAN CELL; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN CONFORMATION; PROTEIN PHOSPHORYLATION; PROTEIN STRUCTURE; REGULATORY MECHANISM; RETINOBLASTOMA; TUMOR SUPPRESSOR GENE;

AMINO ACID SEQUENCE; CELL CYCLE; CYCLIN A; CYCLIN-DEPENDENT KINASES; ELECTROPHORESIS, POLYACRYLAMIDE GEL; HUMANS; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; PHOSPHORYLATION; PROTEIN CONFORMATION; RETINOBLASTOMA PROTEIN; SERINE; STRUCTURE-ACTIVITY RELATIONSHIP; TUMOR CELLS, CULTURED; URINARY BLADDER NEOPLASMS;

EID: 0033515543     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.274.14.9463     Document Type: Article

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