Tolerance of arc repressor to multiple-alanine substitutions

Proceedings of the National Academy of Sciences of the United States of America

Volumn 96, Issue 5, 1999, Pages 1983-1988

  Brown, Bronwen M ^a   Sauer, Robert T ^a  

^a MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

Fast folding mutants; Heterodimer formation; Hyper stable mutants; Nonadditivity; Operator DNA binding

Indexed keywords

ALANINE;

AMINO ACID SUBSTITUTION; ARTICLE; DIMERIZATION; DISSOCIATION CONSTANT; DNA BINDING; HYDROGEN BOND; NUCLEAR MAGNETIC RESONANCE; PRIORITY JOURNAL; PROTEIN DENATURATION; PROTEIN FOLDING; PROTEIN STABILITY; REPRESSOR GENE; SITE DIRECTED MUTAGENESIS;

ALANINE; AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; CIRCULAR DICHROISM; DIMERIZATION; DNA-BINDING PROTEINS; GUANIDINE; HEAT; KINETICS; MACROMOLECULAR SUBSTANCES; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; PROTEIN DENATURATION; PROTEIN FOLDING; PROTEIN STRUCTURE, SECONDARY; REPRESSOR PROTEINS; THERMODYNAMICS; UREA; VIRAL PROTEINS;

EID: 0033514919     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.96.5.1983     Document Type: Article

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