Phentermine and other monoamine-oxidase inhibitors may increase plasma serotonin when given with fenfluramines

Lancet

Volumn 353, Issue 9146, 1999, Pages 38-

  Maher, Timothy J ^a   Ulus, Ismail H ^b   Wurtman, Richard J ^b  

^a MASSACHUSETTS COLLEGE OF PHARMACY AND HEALTH SCIENCES   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

ANOREXIGENIC AGENT; DOPAMINE; ERGOTAMINE; FENFLURAMINE; MONOAMINE; MONOAMINE OXIDASE INHIBITOR; NORADRENALIN; PHENTERMINE; SEROTONIN;

ARTICLE; CELL LEVEL; DOPAMINE RELEASE; ENTEROCHROMAFFIN CELL; ENZYME LINKED IMMUNOSORBENT ASSAY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; METABOLISM; OBESITY; PRIORITY JOURNAL; PULMONARY HYPERTENSION; RADIOIMMUNOASSAY; SEROTONIN BLOOD LEVEL; SYMPATHETIC NERVE CELL; THROMBOCYTE; VALVULAR HEART DISEASE;

EID: 0033514006     PISSN: 01406736     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0140-6736(05)74870-4     Document Type: Article

References (5)

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2. 2 Balcioglu A, Wurtman RJ. Effects of phentermine on striatal dopamine and serotonin release in conscious rats: in vivo microdialysis study. Int J Obesity 1998; 22: 325-328.
3. 3 Manz B, Lorey M, Heyn S, et al. New radioimmunoassays for epinephrine and norepinephrine in plasma and urine as well as metanephrines and normetanephrines in urine. GIT Labor Medizin 1990; 5: 245-263.
4. 4 Moller Nielsen I, Dubnick B. Pharmacology of chlorphentermine. In: Amphetamines and Related Compounds (E Costa, S Garattini, eds) Raven Press, NY, 1970, pp 63-73.
5. 5 Morita T, Mehendale HM. Effects of chlorphentermine and phentermine on the pulmonary disposition of 5-hydroxytrypamine in the rat in vivo. Am Rev Respir Dis 1983; 127: 747-750.