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Volumn 77, Issue 12, 1999, Pages 943-949

Ligand-independent negative chronotropic responses of rat and mouse right atria to β-adrenoceptor antagonists

Author keywords

Catecholamines; Chronotropic responses; ICI 118,551; Inverse agonism; 1 adrenoceptor selective antagonists

Indexed keywords

3 ISOPROPYLAMINO 1 (7 METHYL 4 INDANYLOXY) 2 BUTANOL; ACEBUTOLOL; ALPRENOLOL; ATENOLOL; BETA 1 ADRENERGIC RECEPTOR BLOCKING AGENT; BETA 2 ADRENERGIC RECEPTOR BLOCKING AGENT; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; ISOPRENALINE; METOPROLOL; NADOLOL; NORADRENALIN; PINDOLOL; PROPRANOLOL; RESERPINE; SALBUTAMOL; TIMOLOL;

EID: 0033513364     PISSN: 00084212     EISSN: None     Source Type: Journal    
DOI: 10.1139/y99-099     Document Type: Article
Times cited : (9)

References (30)
  • 1
    • 84951653316 scopus 로고
    • A study of the adrenotropic receptors
    • Ahlquist, R.P. 1948. A study of the adrenotropic receptors. Am. J. Physiol. 153: 586-600.
    • (1948) Am. J. Physiol. , vol.153 , pp. 586-600
    • Ahlquist, R.P.1
  • 2
    • 0017238278 scopus 로고
    • Dissociation constants and relative efficacies of agonists acting on alpha adrenergic receptors in rabbit aorta
    • Besse, J.C., and Furchgott, R.F. 1976. Dissociation constants and relative efficacies of agonists acting on alpha adrenergic receptors in rabbit aorta. J. Pharmacol. Exp. Ther. 197: 66-78.
    • (1976) J. Pharmacol. Exp. Ther. , vol.197 , pp. 66-78
    • Besse, J.C.1    Furchgott, R.F.2
  • 4
    • 0014197728 scopus 로고
    • Evaluation of the cardiac effects of several beta adrenergic blocking agents
    • Blinks, J.R. 1967. Evaluation of the cardiac effects of several beta adrenergic blocking agents. Ann. N.Y. Acad. Sci. 139: 673-685.
    • (1967) Ann. N.Y. Acad. Sci. , vol.139 , pp. 673-685
    • Blinks, J.R.1
  • 6
    • 0025851462 scopus 로고
    • 2-adrenoceptors in the human heart: Properties, function, and alterations in chronic heart failure
    • 2-adrenoceptors in the human heart: properties, function, and alterations in chronic heart failure. Pharmacol. Rev. 43: 203-242.
    • (1991) Pharmacol. Rev. , vol.43 , pp. 203-242
    • Brodde, O.E.1
  • 10
    • 0022541659 scopus 로고
    • 'Inverse agonists', cooperativity and drug action at benzodiazepine receptors
    • Ehlert, F.J. 1986. 'Inverse agonists', cooperativity and drug action at benzodiazepine receptors. Trends Pharmacol. Sci. 7: 28-32.
    • (1986) Trends Pharmacol. Sci. , vol.7 , pp. 28-32
    • Ehlert, F.J.1
  • 11
    • 0028169068 scopus 로고
    • Unoccupied β-adrenoceptor-induced adenylyl cyclase stimulation in turkey erythrocyte membranes
    • Gotze, K., and Jakobs, K.H. 1994. Unoccupied β-adrenoceptor-induced adenylyl cyclase stimulation in turkey erythrocyte membranes. Eur. J. Pharmacol. 268: 151-158.
    • (1994) Eur. J. Pharmacol. , vol.268 , pp. 151-158
    • Gotze, K.1    Jakobs, K.H.2
  • 13
    • 0018955996 scopus 로고
    • Differential distribution of beta-1 and beta-2 adrenergic receptors in cat and guinea-pig heart
    • Hedberg, A., Minneman, K.P., and Molinoff, P.B. 1980. Differential distribution of beta-1 and beta-2 adrenergic receptors in cat and guinea-pig heart. J. Pharmacol. Exp. Ther. 213: 503-508.
    • (1980) J. Pharmacol. Exp. Ther. , vol.213 , pp. 503-508
    • Hedberg, A.1    Minneman, K.P.2    Molinoff, P.B.3
  • 14
    • 0000217817 scopus 로고    scopus 로고
    • Catecholamines, sympathomimetic drugs, and adrenergic receptor antagonists
    • Edited by L.G. Hardman, L.E. Limbird, P.B. Molinoff, R.W. Ruddon, and A.G. Gilman. McGraw-Hill, New York
    • Hoffman, B.B., and Lefkowitz, R.J. 1996. Catecholamines, sympathomimetic drugs, and adrenergic receptor antagonists. In Goodman & Gilman's The Pharmacological Basis of Therapeutics. Edited by L.G. Hardman, L.E. Limbird, P.B. Molinoff, R.W. Ruddon, and A.G. Gilman. McGraw-Hill, New York. pp. 199-248.
    • (1996) Goodman & Gilman's The Pharmacological Basis of Therapeutics , pp. 199-248
    • Hoffman, B.B.1    Lefkowitz, R.J.2
  • 15
    • 0028950255 scopus 로고
    • The two-state model of receptor activation
    • Leff, P. 1995. The two-state model of receptor activation. Trends Pharmacol. Sci. 16: 89-97.
    • (1995) Trends Pharmacol. Sci. , vol.16 , pp. 89-97
    • Leff, P.1
  • 16
    • 0027297275 scopus 로고
    • Constitutive activity of receptors coupled to guanine nucleotide regulatory proteins
    • Lefkowitz, R.J., Cotecchia, S., Samama, P., and Costa, T. 1993. Constitutive activity of receptors coupled to guanine nucleotide regulatory proteins. Trends Pharmacol. Sci. 14: 303-307.
    • (1993) Trends Pharmacol. Sci. , vol.14 , pp. 303-307
    • Lefkowitz, R.J.1    Cotecchia, S.2    Samama, P.3    Costa, T.4
  • 17
    • 0027440691 scopus 로고
    • Activation of calcium currents in cardiac myocytes by empty β-adrenoceptors
    • Mewes, T., Dutz, S., Ravens, U., and Jakobs, K.H. 1993. Activation of calcium currents in cardiac myocytes by empty β-adrenoceptors. Circulation, 88: 2916-2922.
    • (1993) Circulation , vol.88 , pp. 2916-2922
    • Mewes, T.1    Dutz, S.2    Ravens, U.3    Jakobs, K.H.4
  • 19
    • 0028861330 scopus 로고
    • Inverse agonism: Pharmacological curiosity or potential therapeutic strategy?
    • Milligan, G., Bond, R.A., and Lee, M. 1995. Inverse agonism: pharmacological curiosity or potential therapeutic strategy? Trends Pharmacol. Sci. 16: 10-13.
    • (1995) Trends Pharmacol. Sci. , vol.16 , pp. 10-13
    • Milligan, G.1    Bond, R.A.2    Lee, M.3
  • 20
    • 0018773009 scopus 로고
    • Simultaneous determination of beta-1 and beta-2-adrenergic receptors in tissues containing both receptor subtypes
    • Minneman, K.P., Hegstrand, L.R., and Molinoff, P.B. 1979. Simultaneous determination of beta-1 and beta-2-adrenergic receptors in tissues containing both receptor subtypes. Mol. Pharmacol. 16: 34-46.
    • (1979) Mol. Pharmacol. , vol.16 , pp. 34-46
    • Minneman, K.P.1    Hegstrand, L.R.2    Molinoff, P.B.3
  • 21
    • 0023936572 scopus 로고
    • Delineation of the distribution of β-adrenergic receptor subtypes in canine myocardium
    • Murphree, S.S., and Saffitz, J.E. 1988. Delineation of the distribution of β-adrenergic receptor subtypes in canine myocardium. Circ. Res. 63: 117-125.
    • (1988) Circ. Res. , vol.63 , pp. 117-125
    • Murphree, S.S.1    Saffitz, J.E.2
  • 22
    • 0019179135 scopus 로고
    • 2-selective adrenoceptor antagonist and can be used to characterize beta-adrenoceptor populations in tissues
    • 2-selective adrenoceptor antagonist and can be used to characterize beta-adrenoceptor populations in tissues. Life Sci. 27: 671-677.
    • (1980) Life Sci. , vol.27 , pp. 671-677
    • O'Donnell, S.R.1    Wanstall, J.C.2
  • 25
    • 0026767427 scopus 로고
    • Reverse intrinsic activity of antagonists on G protein-coupled receptors
    • Schutz, W., and Freissmuth, M. 1992. Reverse intrinsic activity of antagonists on G protein-coupled receptors. Trends Pharmacol. Sci. 13: 376-380.
    • (1992) Trends Pharmacol. Sci. , vol.13 , pp. 376-380
    • Schutz, W.1    Freissmuth, M.2
  • 26
    • 0020569355 scopus 로고
    • Human cardiac beta-adrenergic receptors: Subtype heterogeneity delineated by direct ligand binding
    • Stiles, G.L., Taylor, S., and Lefkowitz, R.J. 1983. Human cardiac beta-adrenergic receptors: subtype heterogeneity delineated by direct ligand binding. Life Sci. 33: 467-473.
    • (1983) Life Sci. , vol.33 , pp. 467-473
    • Stiles, G.L.1    Taylor, S.2    Lefkowitz, R.J.3
  • 27
    • 0028176054 scopus 로고
    • 2-adrenergic receptor activation of G proteins: Evidence for a preoccupied receptor/G protein state
    • 2-adrenergic receptor activation of G proteins: evidence for a preoccupied receptor/G protein state. Mol. Pharmacol. 45: 524-531.
    • (1994) Mol. Pharmacol. , vol.45 , pp. 524-531
    • Tian, W.N.1    Duzic, E.2    Lanier, S.M.3    Deth, R.C.4
  • 28
    • 0032983049 scopus 로고    scopus 로고
    • Inverse agonist activities of β-adrenoceptor antagonists in rat myocardium
    • Varma, D.R., Shen, H., Deng, X.F., Peri, K.G., Chemtob, S., and Mulay, S. 1999. Inverse agonist activities of β-adrenoceptor antagonists in rat myocardium. Br. J. Pharmacol. 1127: 895-902.
    • (1999) Br. J. Pharmacol. , vol.1127 , pp. 895-902
    • Varma, D.R.1    Shen, H.2    Deng, X.F.3    Peri, K.G.4    Chemtob, S.5    Mulay, S.6
  • 29
    • 0027993098 scopus 로고
    • A functional beta-2 adrenoceptor-mediated chronotropic response in isolated guinea pig heart tissue: Selectivity of the potent beta-2 adrenoceptor agonist TA 2005
    • Voss, H.P., Shukrula, S., Wu, T.S., Donnell, D., and Bast, A. 1994. A functional beta-2 adrenoceptor-mediated chronotropic response in isolated guinea pig heart tissue: selectivity of the potent beta-2 adrenoceptor agonist TA 2005. J. Pharmacol. Exp. Ther. 271: 386-389.
    • (1994) J. Pharmacol. Exp. Ther. , vol.271 , pp. 386-389
    • Voss, H.P.1    Shukrula, S.2    Wu, T.S.3    Donnell, D.4    Bast, A.5
  • 30
    • 0021749853 scopus 로고
    • β-adrenoceptor-subtypes in human, rat, guinea pig, and rabbit atria
    • Wilson, C., and Lincoln, C. 1984. β-Adrenoceptor-subtypes in human, rat, guinea pig, and rabbit atria. J. Cardiovasc. Pharmacol. 6: 1216-1221.
    • (1984) J. Cardiovasc. Pharmacol. , vol.6 , pp. 1216-1221
    • Wilson, C.1    Lincoln, C.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.