Nonreceptor interactions in the pharmacology of blood platelets

General Physiology and Biophysics

Volumn 18, Issue SPEC. ISS., 1999, Pages 120-125

  Nosal R ^a   Jancinova V ^a  

^a INSTITUTE OF EXPERIMENTAL PHARMACOLOGY AND TOXICOLOGY   (Slovakia)

Author keywords

Aggregation; ED50 values; Human platelets; Phospholipase a2; Thromboxane

Indexed keywords

ARACHIDONIC ACID; CALCIMYCIN; CHLOROQUINE; DITHIADEN; PHOSPHOLIPASE A2; THROMBOXANE;

ADULT; CELL METABOLISM; CONFERENCE PAPER; CONTROLLED STUDY; CYTOKINE RELEASE; DRUG EFFICACY; DRUG POTENCY; ENZYME ACTIVITY; HUMAN; HUMAN CELL; HUMAN EXPERIMENT; MALE; NORMAL HUMAN; THROMBOCYTE AGGREGATION; THROMBOCYTE AGGREGATION INHIBITION;

ADULT; ARACHIDONIC ACID; BENZOTHIEPINS; BLOOD PLATELETS; CALCIMYCIN; CHLOROQUINE; HUMANS; MALE; MIDDLE AGED; PHOSPHOLIPASES A; PLATELET AGGREGATION; PLATELET AGGREGATION INHIBITORS; THROMBIN; THROMBOXANE B2;

EID: 0033512074     PISSN: 02315882     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (18)

1. El Tahir K. E. (1987): Influence of niridazole and chloroquine on arterial and myometrial prostacyclin synthesis. Brit. J. Pharmacol. 92, 567-572
2. Jančinová V., Nosál' R., Danihelová E. (1994): On the inhibitory effect of chloroquine on blood platelet aggregation. Thromb. Res. 74, 495-504
3. Jančinová V., Nosáf R., Matejka P. (1997): Effect of chloroquine on human blood platelet function. Scripta Med. 70, 65-68
4. 2. J. Biol. Chem. 264, 5768-5775
5. Kroll M. H., Schafer A. I. (1989): Biochemical mechanisms of platelet activation. Blood 74, 1181-1195
6. Kubo M., Hosteller K. Y. (1985): Mechanisms of cationic drug inhibition of purified phospholipase A. Biochemistry USA 24, 6515-6520
7. Lasslo A. (1984): Blood platelet function, medicinal agents and other chemical entities. Feder. Proc. 43, 1382-1289
8. Launay J. M., Bondoux D., Oset-Gasque M. I., Emami S., Mutel V., Haimart M. (1994): Increase of human serotonin uptake by atypical histamine receptor. Amer. J. Physiol. 266, 526-536
9. Mehta J. L., Nichols W. W. (1990): The potential role of thromboxane inhibitors in preventing myocardial injury. Drugs 40, 657-665
10. Nosál' R. (1995): Blood platelets and chloroquine. Platelets 6, 310-316
11. Nosál' R., Jančinová V., Petríková M. (1992): On the relationship between the inhibition of thrombin stimulated aggregation and thromboxane formation in isolated platelets treated with betaadrenoceptor blocking drugs. Thromb. Res. 68, 333-344
12. Nosál' R., Jančinová V., Petríková M. (1995): Chloroquine inhibits stimulated platelets at the arachidonic acid pathway. Thromb. Res. 77, 531-542
13. 1-histamine antagonist dithiaden inhibits human platelet function in vitro. Platelets 8, 175-180
14. Rink T., Sage S. O. (1990). Calcium signaling in platelet activation. Annu. Rev. Physiol. 52, 431-449
15. Schror K. (1995): Antiplatelet drugs. A comparative study. Drugs 50, 7-28
16. Siess W. (1991): Multiple signal-transduction pathways sinergize in platelet activation. News Physiol. Sci. 6, 51-56
17. Spiegel A. (1987): Signal transduction by guanine nucleotide binding proteins. Mol. Cell. Endocrin. 49, 1-16
18. Zovoico G. B., Cragoe E. J., Feinstein M. B. (1986): Regulation of intracellular pH in human platelets. J. Biol. Chem. 261, 13160-13164