Effect of iron chelators with potent anti-proliferative activity on the expression of molecules involved in cell cycle progression and growth

Redox Report

Volumn 4, Issue 6, 1999, Pages 311-312

  Gao, J ^a   Lovejoy, D ^a   Richardson, D R ^a,b  

^a ROYAL BRISBANE AND WOMEN'S HOSPITAL   (Australia)

^b HEART RESEARCH INSTITUTE   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

2 HYDROXY 1 NAPHTHYLALDEHYDE ISONICOTINOYLHYDRAZONE; ANTINEOPLASTIC AGENT; CHELATING AGENT; CYCLIN D1; CYCLOHEXIMIDE; DEFEROXAMINE; GENE PRODUCT; IRON 59; MESSENGER RNA; PHOSPHOTRANSFERASE; PROTEIN P21; PROTEIN P53; PROTEIN SYNTHESIS INHIBITOR; REGULATOR PROTEIN; RETINOBLASTOMA PROTEIN; RNA; THIOSEMICARBAZONE DERIVATIVE; TRANSFERRIN; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL; CELL CYCLE G1 PHASE; CELL CYCLE S PHASE; CELL PROLIFERATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DNA REPAIR; GENE EXPRESSION; HUMAN; HUMAN CELL; IRON CHELATION; IRON TRANSPORT; NEUROBLASTOMA; NEUROEPITHELIOMA; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; PROTEIN RNA BINDING; WESTERN BLOTTING;

EID: 0033511659     PISSN: 13510002     EISSN: None     Source Type: Journal    
DOI: 10.1179/135100099101534990     Document Type: Article

References (2)

1. Richardson DR, Tran E, Ponka P. The potential of iron chelators of the pyridoxal isonicotinoyl hydrazone class as effective antiproliferative agents. Blood 1995; 86: 4295-4306.
2. Richardson DR, Milnes K. The potential of iron chelators of the pyridoxal isonicotinoyl hydrazone class as effective antiproliferative agents. II. The mechanism of action of ligands derived from salicylaldehyde benzoyl hydrazone and 2-hydroxy-1-naphthylaldehyde benzoyl hydrazone. Blood 1997; 89: 3025-3038.