Monitoring brevetoxins during a Gymnodinium breve red tide: Comparison of sodium channel specific cytotoxicity assay and mouse bioassay for determination of neurotoxic shellfish toxins in shellfish extracts

Natural Toxins

Volumn 7, Issue 4, 1999, Pages 157-165

  Dickey, Robert ^a   Jester, Edward ^a   Granade, Ray ^a   Mowdy, Don ^a   Moncreiff, Cynthia ^b   Rebarchik, Dawn ^b   Robl, Martin ^a   Musser, Steven ^a   Poli, Mark ^c  

^a CENTER FOR DRUG EVALUATION AND RESEARCH   (United States)

^b UNIVERSITY OF SOUTHERN MISSISSIPPI   (United States)

^c UNITED STATES ARMY MEDICAL RESEARCH INSTITUTE OF INFECTIOUS DISEASES   (United States)

Author keywords

Brevetoxin metabolism; Brevetoxins; Cytotoxicity; Liquid chromatography mass spectrometry; Mouse bioassay; Neurotoxic shellfish poisoning

Indexed keywords

BREVETOXIN; NEUROTOXIN; SODIUM CHANNEL; SOLVENT;

ANIMAL TISSUE; ARTICLE; BIOASSAY; CONTROLLED STUDY; CYTOTOXICITY TEST; DINOFLAGELLATE; EXTRACTION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; INTERMETHOD COMPARISON; MASS SPECTROMETRY; MOUSE; NONHUMAN; SHELLFISH; UNITED STATES;

ANIMALIA; DINOPHYCEAE; GYMNODINIUM; KARENIA BREVIS;

EID: 0033507499     PISSN: 10569014     EISSN: None     Source Type: Journal    
DOI: 10.1002/(sici)1522-7189(199907/08)7:4<157::aid-nt52>3.0.co;2-%23     Document Type: Article

References (21)