Transcapillary escape rate of albumin is increased and related to haemodynamic changes in normo-albuminuric type 1 diabetic patients

Journal of Hypertension

Volumn 17, Issue 12 SUPPL., 1999, Pages 1911-1916

  Vervoort, Gerald ^a   Lutterman, Jos A ^a   Smits, Paul ^a   Berden, Jo H ^a   Wetzels, Jack F ^a  

^a RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

Albuminuria; Endothelial function; Haemodynamics; Transcapillary escape rate of albumin; Type 1 diabetes mellitus

Indexed keywords

4 AMINOHIPPURIC ACID; ACETYLCHOLINE; ALBUMIN; FRUCTAN; INULIN;

ADULT; BLOOD PRESSURE; BLOOD VESSEL PERMEABILITY; CONFERENCE PAPER; CONTROLLED STUDY; ENDOTHELIUM; FEMALE; FOREARM BLOOD FLOW; GLOMERULUS FILTRATION; HEMODYNAMICS; HUMAN; INSULIN DEPENDENT DIABETES MELLITUS; KIDNEY BLOOD FLOW; MAJOR CLINICAL STUDY; MALE; PLETHYSMOGRAPHY; PRIORITY JOURNAL; PROTEINURIA; URINALYSIS;

EID: 0033506041     PISSN: 02636352     EISSN: None     Source Type: Journal    
DOI: 10.1097/00004872-199917121-00021     Document Type: Conference Paper

References (37)

1. Parving H, Viberti GC, Keen H, Christiansen JS, Lassen NA. Hemodynamic factors in the genesis of diabetic microangiopathy. Metabolism 1983; 32:943-949.
2. Tooke JE. Microvascular function in human diabetes; a physiological perspective. Diabetes 1995; 44:721-726.
3. Deckert T, Feldt-Rasmussen B, Borch-Johnsen K, Jensen T, Kofoed-Enevoldsen A. Albuminuria reflects widespread vascular damage; the Steno hypothesis. Diabetologia 1989; 32:219-226.
4. Feldt-Rasmussen B. Increased transcapillary escape rate of albumin in type 1 (insulin-dependent) diabetic patients with microalbuminuria. Diabetologia 1986; 29:282-286.
5. Lassen NA, Parving H, Rossing N. Filtration as the main mechanism of overall transcapillary protein escape from the plasma. Microvasc Res 1974; 7:1-4.
6. Pappenheimer JR, Renkin EM, Borrero LM. Filtration, diffusion and molecular seiving through peripheral capillary membranes. A contribution to the pore theory of capillary permeability. Am J Physiol 1951 ; 167:13-46.
7. Michel CC. Transport of macromolecules through microvascular walls. Cardiovasc Res 1996; 32:644-653.
8. Levick JR, Smaje LH. An analysis of the permeability of a fenestra. Microvasc Res 1987; 33:233-256.
9. Elliott TG, Cockcroft JR, Groop P, Viberti GC, Ritter JM. Inhibition of nitric oxide synthesis in forearm vasculature of insulin-dependent diabetic patients: blunted vasoconstriction in patients with microalbuminuria. Clin Sci 1993; 85:687-693.
10. van den Born J, Heuvel van den LPWJ, Bakker MAH, Veerkamp JH, Assmann KJM, Weening JJ, et al. Distribution of GBM heparan sulfate proteoglycan core protein and side chains in human glomerular diseases. Kidney Int 1994; 43:454-463.
11. Yokoyama H, Hoyer PE, Hansen PM, van den Born J, Jensen T, Berden JH, et al. Immunohistochemical quantification of heparan sulfate proteoglycan and collagen IV in skeletal muscle capillary basement membranes of patients with diabetic nephropathy. Diabetes 1997; 46:1875-1880.
12. Calver A, Collier J, Vallance P. Inhibition and stimulation of nitric oxide synthesis in the human forearm arterial bed of patients with insulin-dependent diabetes. J Clin Invest 1992; 90:2548-2554.
13. Sandeman DD, Shore A, Tooke JE. Relation of skin capillary pressure in patients with insulin-dependent diabetes mellitus to complications and metabolic control. N Engl J Med 1992; 327:760-764.
14. Rudberg S, Persson B, Dahlquist G. Increased glomerular filtration rate as a predictor of diabetic nephropathy. An 8-year prospective study. Kidney Int 1992; 41:822-828.
15. Patel V, Rassam S, Newsom R, Wiek J, Kohner E. Retinal blood flow in diabetic retinopathy. BMJ 1992; 305:678-683.
16. Pedrinelli R, Taddei S, Spessot M, Salvetti A. Maximal post-ischaemcc forearm vasodilation in human hypertension: a re-assessment of the method. J Hypertens 1987; 5 (suppl 5):S431-S433.
17. Steinberg HO, Brechtel G, Johnson A, Fineberg N, Baron AD. Insulin-mediated skeletal muscle vasodilation is nitric oxide dependent; a novel action of insulin to increase nitric oxide release. J Clin Invest 1994; 94:1172-1179.
18. Vierhapper H, Gasic S, Roden M, Waldhausl W. Increase in skeletal muscle blood flow but not in renal blood flow during euglycemic hyperinsulinemia in man. Hormone Metab Res 1993; 25:438-441.
19. Hilsted J, Christensen NJ. Dual effect of insulin on plasma volume and transcapillary albumin transport. Diabetologia 1992; 35:99-103.
20. Nestler JE, Barlascini CO, Tetrault GA, Fratkin MJ, Clore JN, Blackard WG. Increased transcapillary escape rate of albumin in nondiabetic men in response to hyperinsulinemia. Diabetes 1990; 39:1212-1217.
21. Rongen GA, Smits P, Thien T. N-Monomethyl-L-ARG reduces the forearm vasodilator response to acethylcholine but not to methacholine in humans. J Cardiovasc Pharmacol 1993; 22:884-888.
22. Vervoort G, Wetzels JFM, Lutterman JA, van Doorn LG, Berden JHM, Smits P. Elevated skeletal muscle blood flow in non-complicated type 1 diabetes mellitus: the role of nitric oxide and sympathetic tone. Hypertension 1999; 34:1086-1090.
23. Parving H, Rasmussen SM. Transcapillary escape rate of albumin and plasma volume in short-and long-term juvenile diabetics. Scand J Clin Lab Invest 1973; 32:81-87.
24. MacKinnon JR, O'Brien C, Swa K, Aspinall P, Butt Z, Cameron D. Pulsatile ocular blood flow in untreated diabetic retinopathy. Acta Ophthalmol Scand 1997; 75:661-664.
25. Leinonen H, Matikainen E, Juntunen J. Permeability and morphology of skeletal muscle capillaries in type 1 (insulin-dependent) diabetes mellitus. Diabetologia 1982; 22:158-162.
26. Jensen T. Increased plasma concentration of von Willebrand factor in insulin dependent diabetics with incipient nephropathy. BMJ 1989; 298:27-28.
27. Toop MJ, Dallinger KJ, Jennings PE, Barnett AH. Angiotensin-converting enzyme (ACE): relationship to insulin-dependent diabetes and microangiopathy. Diabetic Med 1986; 3:455-457.
28. Jensen T, Bjerre-Knudsen J, Feldt-Rasmussen B, Deckert T. Features of endothelial dysfunction in early diabetic nephropathy. Lancet 1989; 1:461-463.
29. Fioretto P, Steffes MW, Mauer M. Glomerular structure in nonproteinuric IDDM patients with various levels of albuminuria. Diabetes 1994; 43:1358-1364.
30. Tamsma JT, van den Born J, Bruijn JA, Assmann KJM, Weening JJ, Berden JHM, et al. Expression of glomerular extracellular matrix components in human diabetic nephropathy: decrease of heparan sulphate in the glomerular basement membrane. Diabetologia 1994; 37:313-320.
31. Bent-Hansen L, Feldt Rasmussen B, Kverneland A, Deckert T. Plasma disappearance of glycated and non-glycated albumin in type 1 (insulin-dependent) diabetes mellitus: evidence for charge dependent alterations of the plasma to lymph pathway. Diabetologia 1993; 36:361-363.
32. van den Born J, van Kraats AA, Hill S, Bakker MA, Berden JH. Vessel wall heparan sulfate and transcapillary passage of albumin in experimental diabetes in the rat. Nephrol Dial Transplant 1997; 12 (suppl 2):27-31.
33. van der Pijl JW, Daha MR, van den Born J, Verhagen NA, Lemkes HH, Bucala R, et al. Extracellular matrix in human diabetic nephropathy: reduced expression of heparan sulphate in skin basement membrane. Diabetologia 1998; 41:791-798.
34. Jaap AJ, Shore AC, Gartside IB, Gamble J, Tooke JE. Increased microvascular fluid permeability in young type 1 (insulin-dependent) diabetic patients. Diabetologia 1993; 36:648-652.
35. Jaap AJ, Shore AC, Tooke JE. Differences in microvascular fluid permeability between long-duration type I (insulin-dependent) diabetic patients with and without significant microangiopathy. Clin Sci 1996; 90:113-117.
36. Parving H. Microvascular permeability to plasma proteins in hypertension and diabetes mellitus in man - on the pathogenesis of hypertensive and diabetic microangiopathy. Danish Med Bull 1975; 22:217-233.
37. Hyung Park C, Maack T. Albumin absorption and catabolism by isolated perfused proximal convoluted tubules of the rabbit. J Clin Invest 1984; 73:767-777.