Single nucleotide polymorphic haplotypes of the interleukin-10 5' flanking region are not associated with renal disease or serology in Caucasian patients with systemic lupus erythematosus

Arthritis and Rheumatism

Volumn 42, Issue 9, 1999, Pages 2017-2018

  Crawley, Esther ^a   Woo, Patricia ^a   Isenberg, David A ^b  

^a ROYAL FREE AND UNIVERSITY COLLEGE MEDICAL SCHOOL   (United Kingdom)

^b UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENT COMPONENT C3; DNA ANTIBODY; DOUBLE STRANDED DNA; INTERLEUKIN 10;

ARTICLE; CAUCASIAN; CONTROLLED STUDY; CYTOKINE PRODUCTION; DISEASE ASSOCIATION; DNA FLANKING REGION; GENOTYPE; HAPLOTYPE; HUMAN; HUMAN CELL; KIDNEY DISEASE; MAJOR CLINICAL STUDY; MICROSATELLITE INSTABILITY; MONONUCLEAR CELL; PRIORITY JOURNAL; SEROLOGY; SINGLE NUCLEOTIDE POLYMORPHISM; SYSTEMIC LUPUS ERYTHEMATOSUS;

BASE SEQUENCE; EUROPEAN CONTINENTAL ANCESTRY GROUP; GENOTYPE; HAPLOTYPES; HUMANS; INTERLEUKIN-10; KIDNEY DISEASES; LUPUS ERYTHEMATOSUS, SYSTEMIC; POLYMORPHISM, GENETIC; PROMOTER REGIONS (GENETICS); TRANSCRIPTION, GENETIC;

EID: 0033501875     PISSN: 00043591     EISSN: None     Source Type: Journal    
DOI: 10.1002/1529-0131(199909)42:9<2017::AID-ANR34>3.0.CO;2-I     Document Type: Article

References (13)

1. Houssiau FA, Lefebvre C, Vanden Berghe M, Lambert M, Devogelaer JP, Renauld JC. Serum interleukin 10 titers in systemic lupus erythematosus reflect disease activity. Lupus 1995;4:393-5.
2. Llorente L, Richaud-Patin Y, Couderc J, Alarcon-Segovia D, Ruiz-Soto R, Alcocer-Castillejos N, et al. Dysregulation of interleukin-10 production in relatives of patients with systemic lupus erythematosus. Arthritis Rheum 1997;40:1429-35.
3. Bienvenu J, Doche C, Gutowski MC, Lenoble M, Lepape A, Perdrix JP. Production of proinflammatory cytokines and cytokines involved in the TH1/TH2 balance is modulated by pentoxifylline. J Cardiovasc Pharmacol 1995;25 Suppl 2:S80-4.
4. Turner DM, Williams DM, Sankaran D, Lazarus M, Sinnott PJ, Hutchinson IV. An investigation of polymorphism in the interleukin-10 gene promoter. Eur J Immunogenet 1997;24: 1-8.
5. Lazarus M, Hajeer AH, Turner D, Sinnott P, Worthington J, Ollier WER, et al. Genetic variation in the interleukin 10 gene promoter and systemic lupus erythematosus. J Rheumatol 1997; 24:2314-7.
6. Eskdale J, Gallagher G, Verweij CL, Keijsers V, Westendorp RGJ. Interleukin 10 secretion in relation to human IL-10 locus haplotypes. Proc Natl Acad Sci U S A 1998;95:9465-70.
7. Mehrian R, Quismorio FP Jr, Strassmann G, Stimmler MM, Horwitz DA, Kitridou RC, et al. Synergistic effect between IL-10 and bcl-2 genotypes in determining susceptibility to systemic lupus erythematosus. Arthritis Rheum 1998;41:596-602.
8. Eskdale J, Wordsworth P, Bowman S, Field M, Gallagher G. Association between polymorphisms at the human IL-10 locus and systemic lupus erythematosus. Tissue Antigens 1997;49:635-9.
9. Crawley E, Kay R, Sillibourne J, Patel P, Hutchinson I, Woo P. Polymorphic haplotypes of the interleukin-10 5′ flanking region determine variable interleukin-10 transcription and are associated with particular phenotypes of juvenile rheumatoid arthritis. Arthritis Rheum 1999;42:1101-8.
10. Mok CC, Lanchbury JS, Chan DW, Lau CS. Interleukin-10 promoter polymorphisms in southern Chinese patients with systemic lupus erythematosus. Arthritis Rheum 1998;41:1090-5.
11. Tan EM, Cohen AS, Fries JF, Masi AT, McShane DJ, Rothfield NF, et al. The 1982 revised criteria for the classification of systemic lupus erythematosus. Arthritis Rheum 1982;25:1271-7.
12. Crawley E, Isenberg D, Woo P, Kay R. Interleukin-10 promoter polymorphism and lupus nephritis: comment on the article by Mok et al [letter]. Arthritis Rheum 1999;42:590-1.
13. Tsao BP, Cantor RM, Kalunian KC, Chen C, Badsha H, Singh R, et al. Evidence for linkage of a candidate chromosome 1 region to human systemic lupus erythematosus. J Clin Invest 1997;99:725-31.