메뉴 건너뛰기




Volumn 20, Issue 3, 1999, Pages 187-194

Complement receptor type two (CR2,CR21). A target for influencing the humoral immune response and antigen-trapping

Author keywords

C3; CD21; Complement; EBV; Immunity; Receptor; Structure; Therapy

Indexed keywords

ANTIGEN; CD23 ANTIGEN; COMPLEMENT COMPONENT C3; COMPLEMENT COMPONENT C3D; COMPLEMENT COMPONENT C3D RECEPTOR;

EID: 0033499991     PISSN: 0257277X     EISSN: None     Source Type: Journal    
DOI: 10.1007/bf02790402     Document Type: Review
Times cited : (13)

References (52)
  • 1
    • 0028958669 scopus 로고
    • The CD19/ CR2/TAPA-1 complex of B lymphocytes: Linking natural to acquired immunity
    • 1 Fearon DT, Carter RH: The CD19/ CR2/TAPA-1 complex of B lymphocytes: Linking natural to acquired immunity Annu Rev Immunol 1995;13:127-149.
    • (1995) Annu Rev Immunol , vol.13 , pp. 127-149
    • Fearon, D.T.1    Carter, R.H.2
  • 2
    • 0030176019 scopus 로고    scopus 로고
    • Activation of B lymphocytes: Integrating signals from CD19, CD22 and Fc gamma RIIb1
    • 2 Doody GM, Dempsey PW, Fearon DT: Activation of B lymphocytes: Integrating signals from CD19, CD22 and Fc gamma RIIb1 Curr Opin Immunol 1996;8:378-382.
    • (1996) Curr Opin Immunol , vol.8 , pp. 378-382
    • Doody, G.M.1    Dempsey, P.W.2    Fearon, D.T.3
  • 3
    • 0031921084 scopus 로고    scopus 로고
    • The role of complement and complement receptors in induction and regulation of immunity
    • 3 Carroll MC: The role of complement and complement receptors in induction and regulation of immunity Annu Rev Immunol 1998;16: 545-568.
    • (1998) Annu Rev Immunol , vol.16 , pp. 545-568
    • Carroll, M.C.1
  • 4
    • 0021245419 scopus 로고
    • Expression of C3d receptors during human B cell differentiation: Immunofluorescence analysis with the HB-5 monoclonal antibody
    • 4 Tedder TF, Clement LT, Cooper MD: Expression of C3d receptors during human B cell differentiation: immunofluorescence analysis with the HB-5 monoclonal antibody J Immunol 1984;133: 678-683.
    • (1984) J Immunol , vol.133 , pp. 678-683
    • Tedder, T.F.1    Clement, L.T.2    Cooper, M.D.3
  • 5
    • 0022405823 scopus 로고
    • Human follicular dendritic cells express CR1, CR2, and CR3 complement receptor antigens
    • 5 Reynes M, Aubert JP, Cohen JH, et al.: Human follicular dendritic cells express CR1, CR2, and CR3 complement receptor antigens J Immunol 1985;135:2687-2694.
    • (1985) J Immunol , vol.135 , pp. 2687-2694
    • Reynes, M.1    Aubert, J.P.2    Cohen, J.H.3
  • 7
    • 0022916085 scopus 로고
    • Complement system proteins which interact with C3b or C4b
    • 7 Reid KBM, Bentley PI, Campell RD, et al.: Complement system proteins which interact with C3b or C4b Immunol Today 1986;7: 230-234.
    • (1986) Immunol Today , vol.7 , pp. 230-234
    • Reid, K.B.M.1    Bentley, P.I.2    Campell, R.D.3
  • 9
    • 0023944470 scopus 로고
    • Structure of the human B lymphocyte receptor for C3d and the Epstein-Barr virus and relatedness to other members of the family of C3/C4 binding proteins
    • 9 Weis JJ, Toothaker LE, Smith JA, Weis JH, Fearon DT: Structure of the human B lymphocyte receptor for C3d and the Epstein-Barr virus and relatedness to other members of the family of C3/C4 binding proteins J Exp Med 1988;167: 1047-1066.
    • (1988) J Exp Med , vol.167 , pp. 1047-1066
    • Weis, J.J.1    Toothaker, L.E.2    Smith, J.A.3    Weis, J.H.4    Fearon, D.T.5
  • 10
    • 0023493795 scopus 로고
    • Molecular cloning of the cDNA encoding the Epstein-Barr virus/C3d receptor (complement receptor type two) of human B lymphocytes
    • 10 Moore MD, Cooper NR, Tack BF, Nemerow GR: Molecular cloning of the cDNA encoding the Epstein-Barr virus/C3d receptor (complement receptor type two) of human B lymphocytes Proc Natl Acad Sci U S A 1987;84: 9194-9198.
    • (1987) Proc Natl Acad Sci U S A , vol.84 , pp. 9194-9198
    • Moore, M.D.1    Cooper, N.R.2    Tack, B.F.3    Nemerow, G.R.4
  • 11
    • 0031035199 scopus 로고    scopus 로고
    • Follicular dendritic cells specifically express the long CR2/ CD21 isoform
    • 11 Liu YJ, Xu JC, Debouteiller O, et al.: Follicular dendritic cells specifically express the long CR2/ CD21 isoform J Exp Med 1997; 185:165-170.
    • (1997) J Exp Med , vol.185 , pp. 165-170
    • Liu, Y.J.1    Xu, J.C.2    Debouteiller, O.3
  • 12
    • 0024412763 scopus 로고
    • Structure and function of the complement receptors, CR1 (CD35) and CR2 (CD21)
    • 12 Ahearn JM, Fearon DT: Structure and function of the complement receptors, CR1 (CD35) and CR2 (CD21) Adv Immunol 1989;46: 183-219.
    • (1989) Adv Immunol , vol.46 , pp. 183-219
    • Ahearn, J.M.1    Fearon, D.T.2
  • 14
    • 0025991505 scopus 로고
    • Suppression of the immune response by a soluble complement receptor of B lymphocytes
    • 14 Hebell T, Ahearn JM, Fearon DT: Suppression of the immune response by a soluble complement receptor of B lymphocytes Science 1991;254:102-105.
    • (1991) Science , vol.254 , pp. 102-105
    • Hebell, T.1    Ahearn, J.M.2    Fearon, D.T.3
  • 15
    • 0032104018 scopus 로고    scopus 로고
    • Expression of complement receptors 1 and 2 on follicular dendritic cells is necessary for the generation of a strong antigen-specific IgG response
    • 15 Fang Y, Xu C, Fu YX, Holers VM, Molina H: Expression of complement receptors 1 and 2 on follicular dendritic cells is necessary for the generation of a strong antigen-specific IgG response J Immunol 1998;160:5273-5279.
    • (1998) J Immunol , vol.160 , pp. 5273-5279
    • Fang, Y.1    Xu, C.2    Fu, Y.X.3    Holers, V.M.4    Molina, H.5
  • 16
    • 0031154649 scopus 로고    scopus 로고
    • A novel mechanism of alternative pathway complement activation accounts for the deposition of C3-fragments on CR2-expressing homologous cells
    • 16 Schwendinger MG, Spruth M, Schoch J, Dierich MP, Prodinger WM: A novel mechanism of alternative pathway complement activation accounts for the deposition of C3-fragments on CR2-expressing homologous cells J Immunol 1997;158:5455-5464.
    • (1997) J Immunol , vol.158 , pp. 5455-5464
    • Schwendinger, M.G.1    Spruth, M.2    Schoch, J.3    Dierich, M.P.4    Prodinger, W.M.5
  • 17
    • 0028825476 scopus 로고
    • Follicular dendritic cells and human immunodeficiency virus infectivity
    • 17 Heath SL, Tew JG, Szakal AK, Burton GF: Follicular dendritic cells and human immunodeficiency virus infectivity [see comments] Nature 1995;377:740-744.
    • (1995) Nature , vol.377 , pp. 740-744
    • Heath, S.L.1    Tew, J.G.2    Szakal, A.K.3    Burton, G.F.4
  • 18
    • 0027216772 scopus 로고
    • Solution structure of a pair of complement modules by nuclear magnetic resonance
    • 18 Barlow PN, Steinkasserer A, Norman DG, et al: Solution structure of a pair of complement modules by nuclear magnetic resonance J Mol Biol 1993;232:268-284.
    • (1993) J Mol Biol , vol.232 , pp. 268-284
    • Barlow, P.N.1    Steinkasserer, A.2    Norman, D.G.3
  • 19
    • 0021972881 scopus 로고
    • OKB7, a monoclonal antibody that reacts at or near the C3d binding site of human CR2
    • 19 Rao PE, Wright SD, Westberg EF, Goldstein G: OKB7, a monoclonal antibody that reacts at or near the C3d binding site of human CR2 Cell Immunol 1985;93: 549-555.
    • (1985) Cell Immunol , vol.93 , pp. 549-555
    • Rao, P.E.1    Wright, S.D.2    Westberg, E.F.3    Goldstein, G.4
  • 20
    • 0022372535 scopus 로고
    • Identification and characterization of the Epstein-Barr virus receptor on human B lymphocytes and its relationship to the C3d complement receptor (CR2)
    • 20 Nemerow GR, Wolfert R, McNaughton ME, Cooper NR: Identification and characterization of the Epstein-Barr virus receptor on human B lymphocytes and its relationship to the C3d complement receptor (CR2) J Virol 1985;55:347-351.
    • (1985) J Virol , vol.55 , pp. 347-351
    • Nemerow, G.R.1    Wolfert, R.2    McNaughton, M.E.3    Cooper, N.R.4
  • 21
    • 0032211058 scopus 로고    scopus 로고
    • Characterization of C3dg binding to a recess formed between short consensus repeats 1 and 2 of complement receptor type 2 (CR2; CD21)
    • 21 Prodinger WM, Schwendinger MG, Schoch J, Köchle M, Larcher C, Dierich MP: Characterization of C3dg Binding to a Recess Formed between Short Consensus Repeats 1 and 2 of Complement Receptor Type 2 (CR2; CD21) J Immunol 1998;161:4604-4610.
    • (1998) J Immunol , vol.161 , pp. 4604-4610
    • Prodinger, W.M.1    Schwendinger, M.G.2    Schoch, J.3    Köchle, M.4    Larcher, C.5    Dierich, M.P.6
  • 22
    • 0031474955 scopus 로고    scopus 로고
    • Expression in insect cells of the functional domain of CD21 (complement receptor type two) as a truncated soluble molecule using a baculovirus vector
    • 22 Prodinger WM, Schoch J, Schwendinger MG, et al.: Expression in insect cells of the functional domain of CD21 (complement receptor type two) as a truncated soluble molecule using a baculovirus vector Immunopharmacology 1997;38:141-148.
    • (1997) Immunopharmacology , vol.38 , pp. 141-148
    • Prodinger, W.M.1    Schoch, J.2    Schwendinger, M.G.3
  • 23
    • 0029073730 scopus 로고
    • Characterization of a complement receptor 2 (CR2, CD21) ligand binding site for C3 an initial model of ligand interaction with two linked short consensus repeat modules
    • 23 Molina H, Perkins SJ, Guthridge J, Gorka J, Kinoshita T, Holers VM: Characterization of a complement receptor 2 (CR2, CD21) ligand binding site for C3 An initial model of ligand interaction with two linked short consensus repeat modules J Immunol 1995; 154:5426-5435.
    • (1995) J Immunol , vol.154 , pp. 5426-5435
    • Molina, H.1    Perkins, S.J.2    Guthridge, J.3    Gorka, J.4    Kinoshita, T.5    Holers, V.M.6
  • 24
    • 0025751635 scopus 로고
    • Determination of the structural basis for selective binding of Epstein-Barr virus to human complement receptor type 2
    • 24 Martin DR, Yuryev A, Kalli KR, Fearon DT, Ahearn JM: Determination of the structural basis for selective binding of Epstein-Barr virus to human complement receptor type 2 J Exp Med 1991;174: 1299-1311.
    • (1991) J Exp Med , vol.174 , pp. 1299-1311
    • Martin, D.R.1    Yuryev, A.2    Kalli, K.R.3    Fearon, D.T.4    Ahearn, J.M.5
  • 25
    • 0025883254 scopus 로고
    • Analysis of Epstein-Barr virus-binding sites on complement receptor 2 (CR2/CD21) using human-mouse chimeras and peptides at least two distinct sites are necessary for ligand-receptor interaction
    • 25 Molina H, Brenner C, Jacobi S, et al.: Analysis of Epstein-Barr virus-binding sites on complement receptor 2 (CR2/CD21) using human-mouse chimeras and peptides At least two distinct sites are necessary for ligand-receptor interaction J Biol Chem 1991;266: 12173-12179.
    • (1991) J Biol Chem , vol.266 , pp. 12173-12179
    • Molina, H.1    Brenner, C.2    Jacobi, S.3
  • 26
    • 0024399050 scopus 로고
    • Hydrodynamic, electron microscopic, and ligand-binding analysis of the Epstein-Barr virus/C3dg receptor (CR2)
    • 26 Moore MD, DiScipio RG, Cooper NR, Nemerow GR: Hydrodynamic, electron microscopic, and ligand-binding analysis of the Epstein-Barr virus/C3dg receptor (CR2) J Biol Chem 1989;264: 20576-20582.
    • (1989) J Biol Chem , vol.264 , pp. 20576-20582
    • Moore, M.D.1    DiScipio, R.G.2    Cooper, N.R.3    Nemerow, G.R.4
  • 27
    • 0032557324 scopus 로고    scopus 로고
    • X-ray crystal structure of C3d: A C3 fragment and ligand for complement receptor 2
    • 27 Nagar B, Jones RG, Diefenbach RJ, Isenman DE, Rini JM: X-ray crystal structure of C3d: a C3 fragment and ligand for complement receptor 2 Science 1998;280:1277-1281.
    • (1998) Science , vol.280 , pp. 1277-1281
    • Nagar, B.1    Jones, R.G.2    Diefenbach, R.J.3    Isenman, D.E.4    Rini, J.M.5
  • 28
    • 0009247302 scopus 로고
    • Mapping of the C3d receptor (CR2)-binding site and a neoantigenic site in the C3d domain of the third component of complement
    • 28 Lambris JD, Ganu VS, Hirani S, Müller-Eberhard HJ: Mapping of the C3d receptor (CR2)-binding site and a neoantigenic site in the C3d domain of the third component of complement Proc Natl Acad Sci U S A 1985;82:4235-4239.
    • (1985) Proc Natl Acad Sci U S A , vol.82 , pp. 4235-4239
    • Lambris, J.D.1    Ganu, V.S.2    Hirani, S.3    Müller-Eberhard, H.J.4
  • 29
    • 0020659816 scopus 로고
    • Studies of the Epstein Barr virus receptor found on Raji cells II A comparison of lymphocyte binding sites for Epstein Barr virus and C3d
    • 29 Hull-Fletcher LM, Fowler E, Lambris JD, Feighny RJ, Simmons JG, Ross GD: Studies of the Epstein Barr virus receptor found on Raji cells II A comparison of lymphocyte binding sites for Epstein Barr virus and C3d J Immunol 1983; 130:1309-1312.
    • (1983) J Immunol , vol.130 , pp. 1309-1312
    • Hull-Fletcher, L.M.1    Fowler, E.2    Lambris, J.D.3    Feighny, R.J.4    Simmons, J.G.5    Ross, G.D.6
  • 30
    • 0023183629 scopus 로고
    • Identification of gp350 as the viral glycoprotein mediating attachment of Epstein-Barr viras (EBV) to the EBV/C3d receptor of B cells: Sequence homology of gp350 and C3 complement fragment C3d
    • 30 Nemerow GR, Mold C, Schwend VK,Tollefson V, Cooper NR: Identification of gp350 as the viral glycoprotein mediating attachment of Epstein-Barr viras (EBV) to the EBV/C3d receptor of B cells: sequence homology of gp350 and C3 complement fragment C3d J Virol 1987;61:1416-1420.
    • (1987) J Virol , vol.61 , pp. 1416-1420
    • Nemerow, G.R.1    Mold, C.2    Schwend, V.K.3    Tollefson, V.4    Cooper, N.R.5
  • 31
    • 0023658334 scopus 로고
    • Epstein-Barr virus gp350/220 binding to the B lymphocyte C3d receptor mediates adsorption, capping, and endocytosis
    • 31 Tanner J, Weis J, Fearon D, Whang Y, Kieff E: Epstein-Barr virus gp350/220 binding to the B lymphocyte C3d receptor mediates adsorption, capping, and endocytosis Cell 1987;50:203-213.
    • (1987) Cell , vol.50 , pp. 203-213
    • Tanner, J.1    Weis, J.2    Fearon, D.3    Whang, Y.4    Kieff, E.5
  • 32
    • 0030926278 scopus 로고    scopus 로고
    • Epstein-Barr virus uses HLA class II as a cofactor for infection of B lymphocytes
    • 32 Li Q, Spriggs MK, Kovats S, et al.: Epstein-Barr virus uses HLA class II as a cofactor for infection of B lymphocytes J Virol 1997;71: 4657-1662.
    • (1997) J Virol , vol.71 , pp. 4657-11662
    • Li, Q.1    Spriggs, M.K.2    Kovats, S.3
  • 34
    • 0028181248 scopus 로고
    • CD23 interacts with a new functional extracytoplasmic domain involving N-linked oligosaccharides on CD21
    • 34 Aubry JP, Pochon S, Gauchat JF, et al.: CD23 interacts with a new functional extracytoplasmic domain involving N-linked oligosaccharides on CD21 J Immunol 1994;152:5806-5813.
    • (1994) J Immunol , vol.152 , pp. 5806-5813
    • Aubry, J.P.1    Pochon, S.2    Gauchat, J.F.3
  • 35
    • 0024586548 scopus 로고
    • Soluble forms of CD21 and CD23 antigens in the serum in B cell chronic lymphocytic leukaemia
    • 35 Lowe J, Brown B, Hardie D, Richardson P, Ling N: Soluble forms of CD21 and CD23 antigens in the serum in B cell chronic lymphocytic leukaemia Immunol Lett 1989; 20:103-109.
    • (1989) Immunol Lett , vol.20 , pp. 103-109
    • Lowe, J.1    Brown, B.2    Hardie, D.3    Richardson, P.4    Ling, N.5
  • 37
    • 0029074335 scopus 로고
    • Role of Epstein-Barr virus and soluble CD21 in persistent polyclonal B-cell lymphocytosis
    • 37 Larcher C, Fend F, Mitterer M, Prang N, Schwarzmann F, Huemer HP: Role of Epstein-Barr virus and soluble CD21 in persistent polyclonal B-cell lymphocytosis Br J Haematol 1995;90:532-540.
    • (1995) Br J Haematol , vol.90 , pp. 532-540
    • Larcher, C.1    Fend, F.2    Mitterer, M.3    Prang, N.4    Schwarzmann, F.5    Huemer, H.P.6
  • 38
    • 0029957815 scopus 로고    scopus 로고
    • Human lymphocyte shed a soluble form of CD21 (the C3dg/Epstein-Barr virus receptor, CR2) that binds iC3b and CD23
    • 38 Fremeaux Bacchi V, Bernard I, Maillet F, et al.: Human lymphocyte shed a soluble form of CD21 (the C3dg/Epstein-Barr virus receptor, CR2) that binds iC3b and CD23 Eur J Immunol 1996;26: 1497-1503.
    • (1996) Eur J Immunol , vol.26 , pp. 1497-1503
    • Fremeaux Bacchi, V.1    Bernard, I.2    Maillet, F.3
  • 39
    • 0025812969 scopus 로고
    • Inhibition of Epstein-Barr virus infection in vitro and in vivo by soluble CR2 (CD21) containing two short consensus repeats
    • 39 Moore MD, Cannon MJ, Sewall A, Finlayson M, Okimoto M, Nemerow GR: Inhibition of Epstein-Barr virus infection in vitro and in vivo by soluble CR2 (CD21) containing two short consensus repeats J Virol 1991;65:3559-3565.
    • (1991) J Virol , vol.65 , pp. 3559-3565
    • Moore, M.D.1    Cannon, M.J.2    Sewall, A.3    Finlayson, M.4    Okimoto, M.5    Nemerow, G.R.6
  • 40
    • 0025147480 scopus 로고
    • A molecular and immunochemical characterization of mouse CR2 Evidence for a single gene model of mouse complement receptors 1 and 2
    • 40 Molina H, Kinoshita T, Inoue K, Carel JC, Holers VM: A molecular and immunochemical characterization of mouse CR2 Evidence for a single gene model of mouse complement receptors 1 and 2 J Immunol 1990;145:2974-2983.
    • (1990) J Immunol , vol.145 , pp. 2974-2983
    • Molina, H.1    Kinoshita, T.2    Inoue, K.3    Carel, J.C.4    Holers, V.M.5
  • 41
    • 0025127325 scopus 로고
    • In vivo inhibition of the antibody response by a complement receptor-specific monoclonal antibody
    • 41 Heyman B, Wiersma EJ, Kinoshita T: In vivo inhibition of the antibody response by a complement receptor-specific monoclonal antibody J Exp Med 1990; 172:665-668.
    • (1990) J Exp Med , vol.172 , pp. 665-668
    • Heyman, B.1    Wiersma, E.J.2    Kinoshita, T.3
  • 42
    • 0029007836 scopus 로고
    • Antibodies to murine complement receptor 1 and 2 can inhibit the antibody response in vivo without inhibiting T helper cell induction
    • 42 Gustavsson S, Kinoshita T, Heyman B: Antibodies to murine complement receptor 1 and 2 can inhibit the antibody response in vivo without inhibiting T helper cell induction J Immunol 1995;154: 6524-6528.
    • (1995) J Immunol , vol.154 , pp. 6524-6528
    • Gustavsson, S.1    Kinoshita, T.2    Heyman, B.3
  • 43
    • 15844412034 scopus 로고    scopus 로고
    • Disruption of the Cr2 locus results in a reduction in B-1a cells and in an impaired B cell response to T-dependent antigen
    • 43 Ahearn JM, Fischer MB, Croix D, et al.: Disruption of the Cr2 locus results in a reduction in B-1a cells and in an impaired B cell response to T-dependent antigen Immunity 1996;4:251-262.
    • (1996) Immunity , vol.4 , pp. 251-262
    • Ahearn, J.M.1    Fischer, M.B.2    Croix, D.3
  • 44
    • 0029926153 scopus 로고    scopus 로고
    • Markedly impaired humoral immune response in mice deficient in complement receptors 1 and 2
    • 44 Molina H, Holers VM, Li B, et al.: Markedly impaired humoral immune response in mice deficient in complement receptors 1 and 2 Proc Natl Acad Sci U S A 1996;93: 3357-3361.
    • (1996) Proc Natl Acad Sci U S A , vol.93 , pp. 3357-3361
    • Molina, H.1    Holers, V.M.2    Li, B.3
  • 45
    • 0030901968 scopus 로고    scopus 로고
    • The CD19-CD21 complex regulates signal transduction thresholds governing humoral immunity and autoimmunity
    • 45 Tedder TF, Inaoki M, Sato S: The CD19-CD21 complex regulates signal transduction thresholds governing humoral immunity and autoimmunity Immunity 1997; 6:107-118.
    • (1997) Immunity , vol.6 , pp. 107-118
    • Tedder, T.F.1    Inaoki, M.2    Sato, S.3
  • 46
    • 0031954297 scopus 로고    scopus 로고
    • Infection of human B lymphocytes with lymphocryptoviruses related to Epstein-Barr virus
    • 46 Moghaddam A, Koch J, Annis B, Wang F: Infection of human B lymphocytes with lymphocryptoviruses related to Epstein-Barr virus J Virol 1998;72:3205-3212.
    • (1998) J Virol , vol.72 , pp. 3205-3212
    • Moghaddam, A.1    Koch, J.2    Annis, B.3    Wang, F.4
  • 47
    • 0031919928 scopus 로고    scopus 로고
    • Therapeutic inhibition of the complement system
    • 47 Makrides SC: Therapeutic inhibition of the complement system Pharmacol Rev 1998;50:59-87.
    • (1998) Pharmacol Rev , vol.50 , pp. 59-87
    • Makrides, S.C.1
  • 48
    • 0025354456 scopus 로고
    • Soluble human complement receptor type I: In vivo inhibitor of complement suppressing post-ischemic myocardial inflammation and necrosis
    • 48 Weisman HF, Barlow T, Leppo MK, et al.: Soluble human complement receptor type I: in vivo inhibitor of complement suppressing post-ischemic myocardial inflammation and necrosis Science 1990;249:146-151.
    • (1990) Science , vol.249 , pp. 146-151
    • Weisman, H.F.1    Barlow, T.2    Leppo, M.K.3
  • 49
    • 0028120820 scopus 로고
    • Therapeutic uses of recombinant complement protein inhibitors Springer
    • 49 Kalli KR, Hsu P, Fearon DT: Therapeutic uses of recombinant complement protein inhibitors Springer Semin Immunopathol 1994;15: 417-431.
    • (1994) Semin Immunopathol , vol.15 , pp. 417-431
    • Kalli, K.R.1    Hsu, P.2    Fearon, D.T.3
  • 50
    • 0029188184 scopus 로고
    • First EBV vaccine trial in humans using recombinant vaccinia virus expressing the major membrane antigen
    • 50 Gu SY, Huang TM, Ruan L, et al: First EBV vaccine trial in humans using recombinant vaccinia virus expressing the major membrane antigen Dev Biol Stand 1995; 84:171-177.
    • (1995) Dev Biol Stand , vol.84 , pp. 171-177
    • Gu, S.Y.1    Huang, T.M.2    Ruan, L.3
  • 51
    • 0019223713 scopus 로고
    • Monoclonal antibody against a 250,000-dalton glycoprotein of a Epstein-Barr virus identifies a membrane antigen and a neutralizing antigen
    • 51 Hoffman GJ, Lazarowitz SG, Hayward SD: Monoclonal antibody against a 250,000-dalton glycoprotein of a Epstein-Barr virus identifies a membrane antigen and a neutralizing antigen Proc Natl Acad Sci U S A 1980;77:2979-2983.
    • (1980) Proc Natl Acad Sci U S A , vol.77 , pp. 2979-2983
    • Hoffman, G.J.1    Lazarowitz, S.G.2    Hayward, S.D.3
  • 52
    • 0030593030 scopus 로고    scopus 로고
    • C3d of complement as a molecular adjuvant: Bridging innate and acquired immunity
    • 52 Dempsey PW, Allison MED, Akkaraju S, Goodnow CC, Fearon DT: C3d of complement as a molecular adjuvant: Bridging innate and acquired immunity. Science 1996;271:348-350.
    • (1996) Science , vol.271 , pp. 348-350
    • Dempsey, P.W.1    Allison, M.E.D.2    Akkaraju, S.3    Goodnow, C.C.4    Fearon, D.T.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.