Serum levels of hepatitis C virus RNA in infants and children with chronic hepatitis C

Journal of Pediatric Gastroenterology and Nutrition

Volumn 29, Issue 3, 1999, Pages 314-317

  Azzari, Chiara ^c   Resti, Massimo ^c   Bortolotti, Flavia ^a   Moriondo, Maria ^c   Crivellaro, Carlo ^b   Lionetti, Paolo ^c   Vierucci, Alberto ^c  

^a UNIVERSITY OF PADOVA   (Italy)

^b Department of Pediatrics   (Italy)

^c Department of Pediatrics ^*

Author keywords

Children; Chronic hepatitis; Hepatitis C virus; Vertical infection; Viral load

Indexed keywords

VIRUS RNA;

ARTICLE; CHILD; CLINICAL ARTICLE; FEMALE; FOLLOW UP; HEPATITIS C; HEPATITIS C VIRUS; HUMAN; MALE; PRIORITY JOURNAL; VIREMIA; VIRUS CARRIER; VIRUS DETECTION; VIRUS DIAGNOSIS; VIRUS LOAD;

ADOLESCENT; ALANINE TRANSAMINASE; CHILD; CHILD, PRESCHOOL; FEMALE; HEPACIVIRUS; HEPATITIS C ANTIBODIES; HEPATITIS C, CHRONIC; HUMANS; MALE; RNA, VIRAL;

HEPATITIS C VIRUS;

EID: 0033499436     PISSN: 02772116     EISSN: None     Source Type: Journal    
DOI: 10.1097/00005176-199909000-00014     Document Type: Article

References (24)

1. Kato N, Yokosuka O, Hosoda K, Ito Y, Ohto M, Omata M. Quantification of hepatitis C virus by competitive reverse transcription-polymerase chain reaction: Increase of the virus in advanced liver disease. Hepatology 1993;18:16-20.
2. Gunji T, Kato N, Mori S, et al. Correlation between the serum level of hepatitis C virus RNA and disease activities in acute and chronic hepatitis C. Int J Cancer 1992;52:726-30.
3. Kumar U, Thomas HC, Monjardino J. Serum HCV-RNA levels in chronic HCV hepatitis measured by quantitative PCR assay correlation With serum AST. J Virol Methods 1994;47:95-102.
4. Naito M, Hayashi N, Hagiwara H, et al. Serum hepatitis C virus RNA quantity and histological features of hepatitis C virus carriers with persistently normal ALT levels. Hepatology 1994;19:871-5
5. McGuiness PH, Bishop GA, Painter DM, Chan R, McCaugan GW. Intrahepatic hepatitis C RNA levels do not correlate with degree of liver injury in patients with chronic hepatitis C. Hepatology 1996; 23:676-87.
6. Chayama K, Tsubota A, Arase Y, et al. Quantitative analysis of hepatitis C virus RNA by competitive nested polymerase chain reaction. J Gastroenterol Hepatol 1993;8:S40-S4.
7. Nguyen TT, Sedghi-Vaziri A, Wilkes LB, et al. Fluctuations in viral load (HCV-RNA) are relatively insignificant in untreated patients with chronic HCV infection. J Viral Hepatol 1996;3:75-8.
8. Gretch D, Corey L, Wilson J, et al. Assessment of hepatitis C virus RNA levels by quantitative competitive RNA polymerase chain reactions high-liter viremia correlates with advanced stage of disease. J Infect Dis 1994;169:1219-25.
9. Martinot-Peignoux M, Marcellin P, Pouteau M, et al. Pretreatment serum hepatitis C virus RNA levels and hepatitis C virus genotypes are the main and independent prognostic factors of sustained response to interferon alfa therapy in chronic hepatitis C. Hepatology 1995;22:1050-6.
10. Shiratori Y, Kato N, Yokosuka O, et al. Quantitative assays for hepatitis C virus in serum as predictors of the long-term response to interferon. J Hepatol 1997;27:437-44.
11. Ohio H, Terazawa S, Sasaki N, et al. Transmission of hepatitis C virus from mothers to infants. N Engl J Med 1994;330:744-50.
12. Desmet VJ, Gerber M, Hoofnagle JH, Manns M, Scheuer PJ. Classification of chronic hepatitis: Diagnosis, grading, and staging. Hepatology 1994;19:1513-20.
13. Resti M, Azzari C, Mannelli F, et al. Mother-to-infant transmission of hepatitis C virus: Prospective study of risk factors and timing of infection in children born to women seronegative for HIV-1. BMJ 1998;317:437-41.
14. Simmonds P. Variability of hepatitis C virus. Hepatology 1995; 21:570-83.
15. Bortolotti F, Resti M, Giacchino R, et al. Features and outcome of hepatitis C virus infection and related liver disease in children of anti-HCV positive mothers. J Pediatr 1997;130:990-3.
16. Guido M, Rugge M, Jara P, et al. Chronic hepatitis C in children: The pathological and clinical spectrum. Gastroenterology 1998; 115:1525-9.
17. Lau JYN, Davis GL, Kniffen J, et al. Significance of serum hepatitis C virus RNA levels in chronic hepatitis C. Lancet 1993;341: 1501-04.
18. Kao JH, Lai MY, Chen PJ, Hwang LH, Chen W, Chen DS. Clinical significance of serum hepatitis C virus titres in patients with chronic type C hepatitis. Am J Gastroenterol 1996;91:506-10.
19. Hayashi J, Kishihara Y, Yoshimura E, et al. Relationship of genotype to level of hepatitis C viraemia determined by competitive polymerase chain reaction. J Infect 1995;30:235-9.
20. Smith DB, Davidson F, Yap PL, et al. Levels of hepatitis C virus in blood donors infected with different viral genotypes. J Infect Dis 1996;173:727-30.
21. Ichijo T, Matsumoto A, Kobayashi M, Furihata K, Tanaka E. Quantitative measurement of HCV RNA in the serum: A comparison of three assays based on different principles. J Gastroenterol Hepatol 1997;12:500-6.
22. Detmer J, Lagier R, Flynn J, et al. Accurate quantification of hepatitis C virus (HCV) RNA from all HGV genotypes by using branched-DNA technology. J Clin Microbiol 1996;34:901-7.
23. Hawkins A, Davidson F, Simmonds P. Comparison of plasma virus loads among individuals infected with hepatitis C virus (HCV) genotypes 1,2, and 3 by quantiplex HCV RNA assay version 1 and 2, Roche Monitor assay, and an in-house limiting dilution method. J Clin Microbiol 1997;35:187-92.
24. National Institutes of Health Consensus Development Conference Panel Statement: Management of hepatitis C. Hepatology 1997; 26:2S-10S.