Plant protein serine/threonine kinases: Classification and functions

Annual Review of Plant Biology

Volumn 50, Issue , 1999, Pages 97-131

  Hardie, D G ^a  

^a UNIVERSITY OF DUNDEE   (United Kingdom)

Author keywords

Cellular signaling; Higher plants; Protein kinases; Sequence families; Signal transduction

Indexed keywords

ANIMALIA; ARABIDOPSIS THALIANA; EMBRYOPHYTA;

EID: 0033499326     PISSN: 15435008     EISSN: None     Source Type: Book Series    
DOI: 10.1146/annurev.arplant.50.1.97     Document Type: Article

References (179)

1. Bachmann M, Huber JL, Athwal GS, Wu K, Ferl RJ, Huber SC. 1996. 14-3-3 proteins associate with the regulatory phosphorylation site of spinach leaf nitrate reductase in an isoform-specific manner and reduce dephosphorylation of ser-543 by endogenous protein phosphatases. FEBS Lett. 398:26-30
2. Ball KL, Barker J, Halford NG, Hardie DG. 1995. Immunological evidence that HMG-CoA reductase kinase-A is the cauliflower homologue of the Rkin 1 subfamily of plant protein kinases. FEBS Lett. 377:189-92
3. Ball KL, Dale S, Weekes J, Hardie DG. 1994. Biochemical characterization of two forms of 3-hydroxy-3-methylglutaryl-CoA reductase kinase from cauliflower (Brassica oleracea). Eur. J. Biochem. 219:743-50
4. Banno H, Hirano K, Nakamura T, Irie K, Nomoto S, et al. 1993. NPK1, a tobacco gene that encodes a protein with a domain homologous to yeast BCK1, STE11, and Byr2 protein kinases. Mol. Cell. Biol. 13:4745-52
5. Barker JHA, Slocombe SP, Ball KL, Hardie DG, Shewry PR, Halford NG. 1996. Evidence that barley HMG-CoA reductase kinase is a member of the SNF1-related protein kinase family. Plant Physiol. 112:1141-49
6. Bender J, Fink GR. 1994. AFC1, a LAMMER kinase from Arabidopsis thaliana, activates STE12-dependent processes in yeast. Proc. Natl. Acad. Sci. USA 91: 12105-9
7. Bent AF. 1996. Plant disease resistance genes - function meets structure. Plant Cell 8:1757-71
8. Bogre L, Ligterink W, Meskiene I, Barker PJ, Heberlebors E, et al. 1997. Wounding induces the rapid and transient activation of a specific MAP kinase pathway. Plant Cell 9:75-83
9. Braun DM, Garcia XU, Stone JM. 1996. Protein phosphorylation: examining the plant CPU. Trends Plant Sci. 1:289-91
10. Braun DM, Stone JM, Walker JC. 1997. Interaction of the maize and Arabidopsis kinase interaction domains with a subset of receptor-like protein kinases: implications for transmembrane signaling in plants. Plant J. 12:83-95
11. Braun DM, Walker JC. 1996. Plant transmembrane receptors - new pieces in the signaling puzzle. Trends Biochem. Sci. 21:70-73
12. Bush DS. 1995. Calcium regulation in plant cells and its role in signaling. Annu. Rev. Plant Physiol. Plant Mol. Biol. 46:95-122
13. Chang C, Meyerowitz EM. 1995. The ethylene hormone response in Arabidopsis - a eukaryotic 2-component signaling system. Proc. Natl. Acad. Sci. USA 92: 4129-33
14. Clark KL, Larsen PB, Wang XX, Chang C. 1998. Association of the Arabidopsis CTR1 Raf-like kinase with the ETR1 and ERS ethylene receptors. Proc. Natl. Acad. Sci. USA 95:5401-6
15. Clark SE, Williams RW, Meyerowitz EM. 1997. The CLAVATA1 gene encodes a putative receptor kinase that controls shoot and floral meristem size in Arabidopsis. Cell 89:575-85
16. Cobb MH. 1995. Casein kinase 1 (vertebrates). In The Protein Kinase Factsbook, ed. DG Hardie, SK Hanks, pp. 1:347-49. London: Academic
17. Collinge MA, Walker JC. 1994. Isolation of an Arabidopsis thaliana casein kinase II β subunit by complementation in Saccharomyces cerevisiae. Plant Mol. Biol. 25:649-58
18. Cook D, Fry MJ, Hughes K, Sumathipala R, Woodgett JR, Dale TC. 1996. Wingless inactivates glycogen synthase kinase3 via an intracellular signalling pathway which involves a protein kinase C. EMBO J. 15:4526-36
19. Corton JM, Gillespie JG, Hardie DG. 1994. Role of the AMP-activated protein kinase in the cellular stress response. Curr. Biol. 4:315-24
20. Cross DA, Alessi DR, Cohen P, Andjelkovich M, Hemmings BA. 1995. Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B. Nature 378:785-89
21. Dale S, Arró M, Becerra B, Morrice NG, Boronat A, et al. 1995. Bacterial expression of the catalytic domain of 3-hydroxy-3-methylglutaryl CoA reductase (isoform HMGR1) from Arabidopsis thaliana, and its inactivation by phosphorylation at serine-577 by Brassica oleracea 3-hydroxy-3-methylglutaryl CoA reductase kinase. Eur. J. Biochem. 233:506-13
22. Dale S, Wilson WA, Edelman AM, Hardie DG. 1995. Similar substrate recognition motifs for mammalian AMP-activated protein kinase, higher plant HMG-CoA reductase kinase-A, yeast SNF1, and mammalian calmodulin-dependent protein kinase I. FEBS Lett. 361:191-95
23. Day IS, Reddy ASN. 1998. Isolation and characterization of two cyclin-like cDNAs from Arabidopsis. Plant Mol. Biol. 36:451-61
24. de Veylder L, Segers G, Glab N, Casteels P, Van Montagu M, Inze D. 1997. The Arabidopsis Cks 1 At protein binds the cyclin-dependent kinases Cdc2aAt and Cdc2bAt. FEBS Lett. 412:446-52
25. Decroocqferrant V, Vanwent J, Bianchi MW, Devries SC, Kreis M. 1995. Petunia hybrida homologs of shaggy/zeste-white-3 expressed in female and male reproductive organs. Plant J. 7:897-911
26. Deeken R, Kaldenhoff R. 1997. Lightrepressible receptor protein kinase: a novel photo-regulated gene from Arabidopsis thaliana. Planta 202:479-86
27. DeMaggio AJ, Lindberg RA, Hunter T, Hoekstra MF. 1992. The budding yeast HRR25 gene product is a casein kinase I isoform. Proc. Natl. Acad. Sci. USA 89:7008-12
28. Devereux J, Haeberli P, Smithies O. 1984. A comprehensive set of sequence analysis programs for the VAX. Nucleic Acids Res. 12:387-95
29. Deleted in proof
30. Doonan J, Fobert P. 1997. Conserved and novel regulators of the plant cell cycle. Curr. Opin. Cell Biol. 9:824-30
31. Dornelas MC, Lejeune B, Dron M, Kreis M. 1998. The Arabidopsis SHAGGY-related protein kinase (ASK) gene family: structure, organization and evolution. Gene 212:249-57
32. Douglas P, Moorhead G, Hong Y, Morrice N, MacKintosh C. 1998. Purification of a nitrate reductase kinase from Spinacia oleracea leaves, and its identification as a calmodulin-domain protein kinase. Planta 206:435-42
33. Einzenberger E, Eller N, Heberlebors E, Vicente O. 1995. Isolation and expression during pollen development of a tobacco cDNA clone encoding a protein kinase homologous to shaggy glycogen synthase kinase-3. Biochim. Biophys. Acta 1260:315-19
34. Espunya MC, Martinez MC. 1997. Identification of two different molecular forms of Arabidopsis thaliana casein kinase II. Plant Sci. 124:131-42
35. Feiler HS, Jacobs TW. 1990. Cell division in higher plants: a cdc2 gene, its 34 kDa product, and histone H1 kinase activity in pea. Proc. Natl. Acad. Sci. USA 87:5397-401
36. Ferreira PCG, Hemerly AS, Villarroel R, Vanmontagu M, Inze D. 1991. The Arabidopsis functional homolog of the p34cdc2 protein kinase. Plant Cell 3:531-40
37. Flotow H, Roach PJ. 1989. Synergistic phosphorylation of rabbit muscle glycogen synthase by cyclic AMP-dependent protein kinase and casein kinase I. Implications for hormonal regulation of glycogen synthase. J. Biol. Chem. 264:9126-9128
38. Fobert PR, Gaudin V, Lunness P, Coen ES, Doonan JH. 1996. Distinct classes of cdc2-related genes are differentially expressed during the cell-division cycle in plants. Plant Cell 8:1465-76
39. Furumoto T, Ogawa N, Hata S, Izui K. 1996. Plant calcium-dependent protein kinase-related kinases (CRKs) do not require calcium for their activities. FEBS Lett. 396:147-51
40. Goldberg J, Nairn AC, Kuriyan J. 1996. Structural basis for the autoinhibition of calcium/calmodulin-dependent protein kinase I. Cell 84:875-87
41. Grafi G, Burnett RJ, Helentjaris T, Larkins BA, Decaprio JA, et al. 1996. A maize cDNA-encoding a member of the retinoblastoma protein family -involvement in endoreduplication. Proc. Natl. Acad. Sci. USA 93:8962-67
42. Graham IA, Denby KJ, Leaver CJ. 1994. Carbon catabolite repression regulates glyoxylase cycle gene expression in cucumber. Plant Cell 6:761-72
43. Gu TS, Mazzurco M, Sulaman W, Matias DD, Goring DR. 1998. Binding of an arm repeat protein to the kinase domain of the S-locus receptor kinase. Proc. Natl. Acad. Sci. USA 95:382-87
44. Halford NG, Hardie DG. 1998. SNF1-related protein kinases: global regulators of carbon metabolism in plants? Plant Mol. Biol. 37:735-48
45. Hanks SK. 1987. Homology probing: identification of cDNA clones encoding members of the protein-serine kinase family. Proc. Natl. Acad. Sci. USA 84:388-92
46. Hanks SK, Hunter T. 1995. The eukaryotic protein kinase superfamily: kinase (catalytic) domain structure and classification. FASEB J. 9:576-96
47. Hanna DE, Rethinaswamy A, Glover CV. 1995. Casein kinase II is required for cell cycle progression during G1 and G2/M in Saccharomyces cerevisiae. J. Biol. Chem. 270:25905-14
48. Hardie DG. 1988. Pseudosubstrates turn off protein kinases. Nature 335:592-93
49. Hardie DG, Carling D, Carlson M. 1998. The AMP-activated/SNF1 protein kinase subfamily: metabolic sensors of the eukaryotic cell? Annu. Rev. Biochem. 67: 821-55
50. Harmon AC, Putnam-Evans C, Cormier MJ. 1987. A calcium-dependent but calmodulin-independent protein kinase from soybean. Plant Physiol. 83:830-837
51. Harmon AC, Yoo BC, McCaffery C. 1994. Pseudosubstrate inhibition of CDPK, a protein kinase with a calmodulin-like domain. Biochemistry 33: 7278-87
52. Harper JF, Huang JF, Lloyd SJ. 1994. Genetic identification of an autoinhibitor in CDPK, a protein kinase with a calmodulin-like domain. Biochemistry 33:7267-77
53. Harper JF, Sussman MR, Schaller GE, Putnam-Evans C, Charbonneau H, Harmon AC. 1991. A calcium-dependent protein kinase with a regulatory domain similar to calmodulin. Science 252:951-954
54. Hartwell J, Smith LH, Wilkins MB, Jenkins GI, Nimmo HG. 1996. Higher plant phosphoenolpyruvate carboxylase kinase is regulated at the level of translatable mRNA in response to light or a circadian rhythm. Plant J. 10:1071-78
55. Hawley SA, Davison M, Woods A, Davies SP, Beri RK, et al. 1996. Characterization of the AMP-activated protein kinase kinase from rat liver, and identification of threonine-172 as the major site at which it phosphorylates and activates AMP-activated protein kinase. J. Biol. Chem. 271:27879-87
56. Hayashida N, Mizoguchi T, Yamaguchi-Shinozaki K, Shinozaki K. 1992. Characterization of a gene that encodes a homolog of protein kinase in Arabidopsis thaliana. Gene 121:325-30
57. He ZH, Fujiki M, Kohorn BD. 1996. A cell wall-associated, receptor-like protein-kinase. J. Biol. Chem. 271:19789-93
58. Hemerly A, Engler JD, Bergounioux C, Vanmontagu M, Engler G, et al. 1995. Dominant negative mutants of the cdc2 kinase uncouple cell division from iterative plant development. EMBO J. 14:3925-36
59. Herve C, Dabos P, Galaud JP, Rouge P, Lescure B. 1996. Characterization of an Arabidopsis thaliana gene that defines a new class of putative plant receptor kinases with an extracellular lectin-like domain. J. Mol. Biol. 258:778-88
60. Higgins DG, Sharp PM. 1988. CLUSTAL: a package for performing multiple sequence alignment on a microcomputer. Gene 73:231-44
61. Hirayama T, Imajuku Y, Anai T, Matsui M, Oka A. 1991. Identification of 2 cell cycle controlling cdc2 gene homologs in Arabidopsis thaliana. Gene 105:159-65
62. Hirayama T, Oka A. 1992. Novel protein kinase of Arabidopsis thaliana (APK1) that phosphorylates tyrosine, serine and threonine. Plant Mol. Biol. 20:653-62
63. Hirt H. 1997. Multiple roles of MAP kinases in plant signal transduction. Trends Plant Sci. 2:11-15
64. Hong Y, Takano M, Liu CM, Gasch A, Chye ML, Chua NH. 1996. Expression of 3 members of the calcium-dependent protein kinase gene family in Arabidopsis thaliana. Plant Mol. Biol 30:1259-75
65. Hu SH, Parker MW, Lei JY, Wilce MCJ, Benian GM, Kemp BE. 1994. Insights into autoregulation from the crystal structure of twitchin kinase. Nature 369:581-84
66. Hua J, Chang C, Sun Q, Meyerowitz EM. 1995. Ethylene insensitivity conferred by Arabidopsis ers gene. Science 269:1712-14
67. Huala E, Oeller PW, Liscum E, Han IS, Larsen E, Briggs WR. 1997. Arabidopsis NPH1: a protein kinase with a putative redox-sensing domain. Science 278:2120-23
68. 2+-dependent protein kinase involves intramolecular binding of a calmodulin-like regulatory domain. Biochemistry 35:13222-30
69. Huber C, Huber JL, Liao PC, Gage DA, McMichael RW, et al. 1996. Phosphorylation of serine-15 of maize leaf sucrose synthase - occurrence in vivo and possible regulatory significance. Plant Physiol. 112:793-802
70. Hunter T. 1987. A thousand and one protein kinases. Cell 50:823-29
71. Hunter T. 1997. Oncoprotein networks. Cell 88:333-46
72. Hwang IW, Goodman HM. 1995. An Arabidopsis thaliana root-specific kinase homolog is induced by dehydration, ABA, and NaCl. Plant J. 8:37-43
73. Ishida R, Iwai M, Marsh KL, Austin CA, Yano T, et al. 1996. Threonine 1342 in human topoisomerase IIalpha is phosphorylated throughout the cell cycle. J. Biol. Chem. 271:30077-82
74. Ito T, Takahashi N, Shimura Y, Okada K. 1997. A serine/threonine protein kinase gene isolated by an in vivo binding procedure using the Arabidopsis floral homeotic gene product, AGAMOUS. Plant Cell Physiol 38:248-58
75. Jang JC, Sheen J. 1994. Sugar sensing in higher plants. Plant Cell 6:1665-79
76. Jeffrey PD, Russo AA, Polyak K, Gibbs E, Hurwitz J, et al. 1995. Mechanism of CDK activation revealed by the structure of a cyclinA-CDK2 complex [see comments]. Nature 376:313-20
77. Jinno A, Tanaka K, Matsushime H, Haneji T, Shibuya M. 1993. Testis-specific MAK protein kinase is expressed specifically in the meiotic phase in spermatogenesis and is associated with a 210-kilodalton cellular phosphoprotein. Mol. Cell. Biol. 13:4146-56
78. Johnson KD, Chrispeels MJ. 1992. Tonoplast-bound protein kinase phosphorylates tonoplast intrinsic protein. Plant Physiol. 100:1787-95
79. Johnson LN, Noble MEM, Owen DJ. 1996. Active and inactive protein kinases: structural basis for regulation. Cell 85:149-58
80. Jonak C, Heberlebors E, Hirt H. 1995. Inflorescence-specific expression of ATK-1, a novel Arabidopsis thaliana homolog of shaggy/glycogen synthase kinase-3. Plant Mol. Biol. 27:217-21
81. Jonak C, Kiegerl S, Ligterink W, Barker PJ, Huskisson NS, Hirt H. 1996. Stress signaling in plants - a mitogen-activated protein kinase pathway is activated by cold and drought. Proc. Natl. Acad. Sci. USA 93:11274-79
82. Jonak C, Kiegerl S, Lloyd C, Chan J, Hirt H. 1995. Mmk2, a novel alfalfa MAP kinase, specifically complements the yeast mpkl function. Mol. Gen. Genet. 248:686-94
83. Kaffman A, Herskowitz I, Tjian R, O'Shea EK. 1994. Phosphorylation of the transcription factor PHO4 by a cyclin-CDK complex, PHO80-PHO85. Science 263:1153-56
84. Kakimoto T. 1996. Ckil, a histidine kinase homolog implicated in cytokinin signal-transduction. Science 274:982-85
85. Kapoor M, Lozano G. 1998. Functional activation of p53 via phosphorylation following DNA damage by UV but not gamma radiation. Proc. Natl. Acad. Sci. USA 95:2834-37
86. Keyse SM. 1998. Protein phosphatases and the regulation of MAP kinase activity. Semin. Cell Dev. Biol. 9:143-52
87. Kieber JJ, Rothenberg M, Roman G, Feldmann KA, Ecker JR. 1993. CTR1, a negative regulator of the ethylene response pathway in Arabidopsis, encodes a member of the raf family of protein kinases. Cell 72:427-41
88. Klimczak LJ, Cashmore AR. 1993. Purification and characterization of casein kinase I from broccoli. Biochem. J. 293:283-88
89. Klimczak LJ, Collinge MA, Farini D, Giuliano G, Walker JC, Cashmore AR. 1995. Reconstitution of Arabidopsis casein kinase II from recombinant subunits and phosphorylation of transcription factor Gbf1. Plant Cell 7:105-15
90. Klimczak LJ, Farini D, Lin C, Ponti D, Cashmore AR, Giuliano G. 1995. Multiple isoforms of Arabidopsis casein kinase I combine conserved catalytic domains with variable carboxyl-terminal extensions. Plant Physiol. 109:687-96
91. Knetsch MLW, Wang M, Snaarjagalska BE, Heimovaaradijkstra S. 1996. Abscisic-acid induces mitogen-activated protein-kinase activation in barley aleurone protoplasts. Plant Cell 8:1061-67
92. Kobe B, Deisenhofer J. 1993. Crystal structure of porcine ribonuclease inhibitor, a protein with leucine-rich repeats. Nature 366:751-56
93. Kobe B, Deisenhofer J. 1994. The leucine-rich repeat: a versatile binding motif. Trends Biochem. Sci. 19:415-21
94. Kohorn BD, Lane S, Smith TA. 1992. An Arabidopsis serine/threonine kinase homologue with an epidermal growth factor repeat selected in yeast for its specificity for a thylakoid membrane protein. Proc. Natl. Acad. Sci. USA 89:10989-92
95. Kretzschmar M, Massague J. 1998. SMADs: mediators and regulators of TGF-beta signaling. Curr. Opin. Genet. Dev. 8:103-11
96. Langland JO, Langland LA, Browning KS, Roth DA. 1996. Phosphorylation of plant eukaryotic initiation factor-2 by the plant-encoded double-stranded RNA-dependent protein kinase, pPKR, and inhibition of protein synthesis in vitro. J. Biol. Chem. 271:4539-44
97. Lawton MA, Yamamoto RT, Hanks SK, Lamb CJ. 1989. Molecular cloning of plant transcripts encoding protein kinase homologs. Proc. Natl Acad. Sci. USA 86:3140-44
98. Lee JW, Zhang Y, Weaver CD, Shomer NH, Louis CF, Roberts DM. 1995. Phosphorylation of nodulin 26 on serine 262 affects its voltage-sensitive channel activity in planar lipid bilayers. J. Biol. Chem. 270:27051-57
99. Lee JY, Yoo BC, Harmon AC. 1998. Kinetic and calcium-binding properties of three calcium-dependent protein kinase isoenzymes from soybean. Biochemistry 37:6801-9
100. Li JM, Chory J. 1997. A putative leucinerich repeat receptor kinase involved in brassinosteroid signal transduction. Cell 90:929-38
101. Ligterink W, Kroj T, zurNieden U, Hirt H, Scheel D. 1997. Receptor-mediated activation of a MAP kinase in pathogen defense of plants. Science 276:2054-57
102. Lindzen E, Choi JH. 1995. A carrot cDNA encoding an atypical protein kinase homologous to plant calcium-dependent protein kinases. Plant Mol. Biol. 28:785-97
103. Loh YT, Martin GB. 1995. The disease resistance gene Pto and the fenthionsensitivity gene Fen encode closely related functional protein kinases. Proc. Natl. Acad. Sci. USA 92:4181-84
104. MacKintosh RW, Davies SP, Clarke PR, Weekes J, Gillespie JG, et al. 1992. Evidence for a protein kinase cascade in higher plants: 3-hydroxy-3-methyl-glutaryl-CoA reductase kinase. Eur. J. Biochem. 209:923-31
105. Madhani HD, Fink GR. 1998. The riddle of MAP kinase signaling specificity. Trends Genet. 14:151-55
106. Maeda T, Wurglermurphy SM, Saito H. 1994. A two-component system that regulates an osmosensing MAP kinase cascade in yeast. Nature 369:242-45
107. Magyar Z, Meszaros T, Miskolczi P, Deak M, Feher A, et al. 1997. Cell cycle phase specificity of putative cyclin-dependent kinase variants in synchronized alfalfa cells. Plant Cell 9:223-35
108. Martin GB, Brommonschenkel SH, Chunwongse J, Frary A, Ganal MW, et al. 1993. Map-based cloning of a protein kinase gene conferring disease resistance in tomato. Science 262:1432-36
109. McKibbin RS, Halford NG, Francis D. 1998. Expression of fission yeast cdc25 alters the frequency of lateral root formation in transgenic tobacco. Plant Mol. Biol. 36:601-12
110. Meskiene I, Bogre L, Glaser W, Balog J, Brandstotter M, et al. 1998. MP2C, a plant protein phosphatase 2C, functions as a negative regulator of mitogen-activated protein kinase pathways in yeast and plants. Proc. Natl. Acad. Sci. USA 95:1938-43
111. Mills GB, Schmandt R, McGill M, Amendola A, Hill M, et al. 1992. Expression of TTK, a novel human protein kinase, is associated with cell proliferation. J. Biol. Chem. 267:16000-6
112. Minden A, Karin M. 1997. Regulation and function of the JNK subgroup of MAP kinases. Biochim. Biophys. Acta 1333:F85-104
113. Mindrinos M, Katagiri F, Yu GL, Ausubel FM. 1994. The A. thaliana disease resistance gene RPS2 encodes a protein containing a nucleotide-binding site and leucine-rich repeats. Cell 78:1089-99
114. Mizoguchi T, Gotoh Y, Nishida E, Yamaguchishinozaki K, Hayashida N, et al. 1994. Characterization of 2 cDNAs that encode MAP kinase homologs in Arabidopsis thaliana and analysis of the possible role of auxin in activating such kinase activities in cultured cells. Plant J. 5:111-22
115. Mizoguchi T, Hayashida N, Yamaguchishinozaki K, Harada H, Shinozaki K. 1992. Nucleotide sequence of a cDNA encoding a protein kinase homolog in Arabidopsis thaliana. Plant Mol. Biol. 18:809-12
116. Mizoguchi T, Hayashida N, Yamaguchishinozaki K, Kamada H, Shinozaki K. 1993. AtMPKs - a gene family of plant MAP kinases in Arabidopsis thaliana. FEBS Lett. 336:440-44
117. Mizoguchi T, Hayashida N, Yamaguchishinozaki K, Kamada H, Shinozaki K. 1995. 2 genes that encode ribosomal protein S6 kinase homologs are induced by cold or salinity stress in Arabidopsis thaliana. FEBS Lett. 358:199-204
118. Mizoguchi T, Irie K, Hirayama T, Hayashida N, Yamaguchishinozaki K, et al. 1996. A gene encoding a mitogen-activated protein kinase kinase kinase is induced simultaneously with genes for a mitogen-activated protein kinase and an S6 ribosomal protein kinase by touch, cold, and water stress in Arabidopsis thaliana. Proc. Natl. Acad. Sci. USA 93: 765-69
119. Mizoguchi T, Yamaguchi-Shinozaki K, Hayashida N, Kamada H, Shinozaki K. 1993. Cloning and characterization of two cDNAs encoding casein kinase II catalytic subunits in Arabidopsis thaliana. Plant Mol. Biol. 21:279-89
120. Moran TV, Walker JC. 1993. Molecular cloning of two novel protein kinase genes from Arabidopsis thaliana. Biochim. Biophys. Acta 1216:9-14
121. Morris PC, Guerrier D, Leung J, Giraudat J. 1997. Cloning and characterisation of MEK1, an Arabidopsis gene encoding a homologue of MAP kinase kinase. Plant Mol. Biol. 35:1057-64
122. Nasrallah JB, Stein JC, Kandasamy MK, Nasrallah ME. 1994. Signaling the arrest of pollen-tube development in selfincompatible plants. Science 266:1505-1508
123. Niefind K, Guerra B, Pinna LA, Issinger OG, Schomburg D. 1998. Crystal structure of the catalytic subunit of protein kinase CK2 from Zea mays at 2.1 Å resolution. EMBO J. 17:2451-62
124. Nishihama R, Banno H, Kawahara E, Irie K, Machida Y. 1997. Possible involvement of differential splicing in regulation of the activity of Arabidopsis ANP1 that is related to mitogen-activated protein kinase kinase kinases (MAPKKKs). Plant J. 12:39-48
125. Ostling J, Ronne H. 1998. Negative control of the Mig1p repressor by Snf1p-dependent phosphorylation in the absence of glucose. Eur. J. Biochem. 252:162-68
126. Paul S, TakezawaD, Poovaiah BW. 1995. Chimeric plant calcium/calmodulin-dependent protein-kinase gene with a neural visinin-like calcium-binding domain. Proc. Natl. Acad. Sci. USA 92: 4897-901
127. Pay A, Jonak C, Bogre L, Meskiene I, Mairinger T, et al. 1993. The MSK family of alfalfa protein kinase genes encodes homologs of shaggy/glycogen-synthase kinase-3 and shows differential expression patterns in plant organs and development. Plant J. 3:847-56
128. Pei ZM, Ward JM, Harper JF, Schroeder JI. 1996. A novel chloride channel in Vicia faba guard cell vacuoles activated by the serine/threonine kinase, CDPK. EMBO J. 15:6564-74
129. Poovaiah BW, Reddy ASN. 1993. Calcium and signal transduction in plants. Crit. Rev. Plant Sci. 12:185-211
130. Popping B, Gibbons T, Watson MD. 1996. The Pisum sativum MAP kinase homologue (PsMAPK) rescues the Saccharomyces cerevisiae hog1 deletion mutant under conditions of high osmotic stress. Plant Mol. Biol. 31:355-63
131. Purcell PC, Smith AM, Halford NG. 1998. Antisense expression of a sucrose non fermenting-1-related protein kinase sequence in potato results in decreased expression of sucrose synthase in tubers and loss of sucrose inducibility of sucrose synthase transcripts in leaves. Plant J. 14:195-202
132. Renaudin JP, Doonan JH, Freeman D, Hashimoto J, Hirt H, et al. 1996. Plant cyclins: a unified nomenclature for plant A-, B-and D-type cyclins based on sequence organization. Plant Mol. Biol. 32:1003-18
133. Rethinaswamy A, Birnbaum MJ, Glover CV. 1998. Temperature-sensitive mutations of the CKA1 gene reveal a role for casein kinase II in maintenance of cell polarity in Saccharomyces cerevisiae. J. Biol. Chem. 273:5869-77
134. Robinson LC, Hubbard EJ, Graves PR, DePaoli Roach AA, Roach PJ, et al. 1992. Yeast casein kinase I homologues: an essential gene pair. Proc. Natl. Acad. Sci. USA 89:28-32
135. Roe JL, Durfee T, Zupan JR, Repetti PP, McLean BG, Zambryski PC. 1997. TOUSLED is a nuclear serine/threonine protein kinase that requires a coiled-coil region for oligomerization and catalytic activity. J. Biol. Chem. 272:5838-45
136. Roe JL, Rivin CJ, Sessions A, Feldmann KA, Zambryski PC. 1993. The Tousled gene in A. thaliana encodes a protein kinase homolog that is required for leaf and flower development. Cell 75:939-50
137. Ronne H. 1995. Glucose repression in fungi. Trends Genet. 11:12-17
138. Sakai H, Hua J, Chen QHG, Chang CR, Medrano LJ, et al. 1998. ETR2 is an ETR1-like gene involved in ethylene signaling in Arabidopsis. Proc. Natl. Acad. Sci. USA 95:5812-17
139. Salmeron JM, Oldroyd GED, Rommens CMT, Scofield SR, Kim HS, et al. 1996. Tomato Prf is a member of the leucinerich repeat class of plant disease resistance genes and lies embedded within the Pto kinase gene cluster. Cell 86:123-33
140. Salt IP, Johnson G, Ashcroft SJH, Hardie DG. 1998. AMP-activated protein kinase is activated by low glucose in cell lines derived from pancreatic β cells, and may regulate insulin release. Biochem. J. 335:533-59
141. Satterlee JS, Sussman MR. 1998. Unusual membrane-associated protein kinases in higher plants. J. Membr. Biol. 164:205-13
142. Seo S, Okamoto N, Seto H, Ishizuka K, Sano H, Ohashi Y. 1995. Tobacco MAP kinase - a possible mediator in wound signal transduction pathways. Science 270:1988-92
143. Shaul O, Vanmontagu M, Inze D. 1996. Regulation of cell-division in Arabidopsis. Crit. Rev. Plant Sci. 15:97-112
144. 2+-dependent protein kinases and stress signal transduction in plants. Science 274:1900-2
145. Shibata W, Banno H, Ito Y, Hirano K, Irie K, et al. 1995. A tobacco protein-kinase, NPK2, has a domain homologous to a domain found in activators of mitogen-activated protein kinases (MAPKKs). Mol. Gen. Genet. 246:401-10
146. 2+-dependent protein kinase family from Paramecium tetraurelia. Purification and characterization. J. Biol. Chem. 268:5940-48
147. Song WY, Wang GL, Chen LL, Kim HS, Pi LY, et al. 1995. A receptor kinase-like protein encoded by the rice disease resistance gene, xa21. Science 270:1804-6
148. Stein JC, Dixit R, Nasrallah ME, Nasrallah JB. 1996. SRK, the stigma-specific S-locus receptor kinase of Brassica, is targeted to the plasma membrane in transgenic tobacco. Plant Cell 8:429-45
149. Stein JC, Howlett B, Boyes DC, Nasrallah ME, Nasrallah JB. 1991. Molecular cloning of a putative receptor protein kinase gene encoded at the self-incompatibility locus of Brassica oleracea. Proc. Natl. Acad. Sci. USA 88: 8816-20
150. Stone JM, Collinge MA, Smith RD, Horn MA, Walker JC. 1994. Interaction of a protein phosphatase with an Arabidopsis serine-threonine receptor kinase. Science 266:793-95
151. Stone JM, Trotochaud AE, Walker JC, Clark SE. 1998. Control of meristem development by CLAVATA1 receptor kinase and kinase-associated protein phosphatase interactions. Plant Physiol. 117:1217-25
152. Stratmann JW, Ryan CA. 1997. Myelin basic protein kinase activity in tomato leaves is induced systemically by wounding and increases in response to systemin and oligosaccharide elicitors. Proc. Natl. Acad. Sci. USA 94:11085-89
153. Sugden C, Donaghy P, Halford NG, Hardie DG. 1999. Two SNF1-related protein kinases from spinach leaf phosphorylate and inactivate HMG-CoA reductase, nitrate reductase and sucrose phosphate synthase. Plant Physiol. In press
154. Takezawa D, Ramachandiran S, Paranjape V, Poovaiah BW. 1996. Dual regulation of a chimeric plant serine threonine kinase by calcium and calciumcalmodulin. J. Biol. Chem. 271:8126-32
155. Torii KU, Mitsukawa N, Oosumi T, Matsuura Y, Yokoyama R, et al. 1996. The Arabidopsis erecta gene encodes a putative receptor protein kinase with extracellular leucine-rich repeats. Plant Cell 8:735-46
156. 2+ dependence and substrate specificities. Arch. Biochem. Biophys. 355:291-300
157. Tregear JW, Jouannic S, Schwebeldugue N, Kreis M. 1996. An unusual protein kinase displaying characteristics of both the serine/threonine and tyrosine families is encoded by the A rabidopsis thaliana gene ATN1. Plant Sci. 117:107-19
158. Umeda M, Bhalerao RP, Schell J, Uchimiya H, Koncz C. 1998. A distinct cyclin-dependent kinase-activating kinase of Arabidopsis thaliana. Proc. Natl. Acad. Sci. USA 95:5021-26
159. Usami S, Banno H, Ito Y, Nishihama R, Machida Y. 1995. Cutting activates a 46-kilodalton protein kinase in plants. Proc. Natl. Acad. Sci. USA 92:8660-64
160. Vidal J, Chollet R. 1997. Regulatory phosphorylation of C-4 PEP carboxylase. Trends Plant Sci. 2:230-37
161. Walker JC. 1994. Structure and function of the receptor-like protein kinases of higher plants. Plant Mol. Biol. 26:1599-609
162. Walker JC, Zhang R. 1990. Relationship of a putative receptor protein kinase from maize to the S-locus glycoproteins of Brassica. Nature 345:743-46
163. Wang H, Fowke LC, Crosby WL. 1997. A plant cyclin-dependent kinase inhibitor gene. Nature 386:451-52
164. Wang PC, Vancura A, Mitcheson TG, Kuret J. 1992. Two genes in Saccharomyces cerevisiae encode a membrane bound form of casein kinase-1. Mol. Biol. Cell 3:275-86
165. Wang XQ, Zafian P, Choudhary M, Lawton M. 1996. The PR5K receptor protein kinase from Arabidopsis thaliana is structurally related to a family of plant defense proteins. Proc. Natl Acad. Sci. USA 93:2598-602
166. Watillon B, Kettmann R, Boxus P, Burny A. 1993. A calcium/calmodulin binding serine/threonine protein kinase homologous to the mammalian Type II calcium/calmodulin-dependent protein-kinase is expressed in plant cells. Plant Physiol. 101:1381-84
167. Williams RW, Wilson JM, Meyerowitz EM. 1997. A possible role for kinase-associated protein phosphatase in the Arabidopsis CLAVATA1 signaling pathway. Proc. Natl. Acad. Sci. USA 94:10467-72
168. Wilson WA, Hawley SA, Hardie DG. 1996. The mechanism of glucose repression/derepression in yeast: SNF1 protein kinase is activated by phosphorylation under derepressing conditions, and this correlates with a high AMP:ATP ratio. Curr. Biol. 6:1426-34
169. Woodgett JR. 1991. A common denominator linking glycogen metabolism, nuclear oncogenes and development. Trends Biochem. Sci. 16:177-81
170. Xie Q, Sanz-Burgos AP, Hannon GJ, Gutierrez C. 1996. Plant cells contain a novel member of the retinoblastoma family of growth regulatory proteins. EMBO J. 15:4900-8
171. Yoo BC, Harmon AC. 1996. Intramolecular binding contributes to the activation of CDPK, a protein kinase with a calmodulin-like domain. Biochemistry 35:12029-37
172. Yun B, Farkas R, Lee K, Rabinow L. 1994. The Doa locus encodes a member of a new protein kinase family and is essential for eye and embryonic development in Drosophila melanogaster. Genes Dev. 8:1160-73
173. Zhang K, Letham DS, John PCL. 1996. Cytokinin controls the cell cycle at mitosis by stimulating the tyrosine dephosphorylation and activation of p34(cdc2)-like hi histone kinase. Planta 200:2-12
174. Zhang SH, Lawton MA, Hunter T, Lamb CJ. 1994. Atpk1, a novel ribosomalprotein kinase gene from Arabidopsis. 1. Isolation, characterization, and expression. J, Biol. Chem. 269:17586-92
175. Zhang SQ, Klessig DF. 1997. Salicylic acid activates a 48-kD MAP kinase in tobacco. Plant Cell 9:809-24
176. 2+-dependent protein kinase. FEBS Lett. 410:126-30
177. Zhao Y, Kappes B, Franklin RM. 1993. Gene structure and expression of an unusual protein kinase from Plasmodium falciparum homologous at its carboxyl terminus with the EF hand calcium-binding proteins. J. Biol. Chem. 268:4347-54
178. Zhou JM, Loh YT, Bressan RA, Martin GB. 1995. The tomato gene Ptil encodes a serine/threonine kinase that is phosphorylated by Pto and is involved in the hypersensitive response. Cell 83:925-35
179. Zhou R. 1998. The Eph family receptors and ligands. Pharmacol. Ther. 77:151-81