Linkage of a marker in intron D of the estrogen synthase locus to rheumatoid arthritis

Arthritis and Rheumatism

Volumn 42, Issue 8, 1999, Pages 1617-1620

  John, Sally ^a   Myerscough, Anne ^a   Eyre, Stephen ^a   Roby, Philip ^a   Hajeer, Ali ^a   Silman, Alan J ^a   Ollier, William E R ^a   Worthington, Jane ^a  

^a UNIVERSITY OF MANCHESTER   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ESTROGEN; SYNTHETASE;

ALLELE; ARTICLE; FAMILY STUDY; FEMALE; FLUORESCENCE ANALYSIS; GENE LOCUS; GENETIC LINKAGE; GENETIC MARKER; GENETIC SUSCEPTIBILITY; GENOTYPE; HUMAN; INTRON; MAJOR CLINICAL STUDY; MALE; ONSET AGE; PRIORITY JOURNAL; RHEUMATOID ARTHRITIS; SEX DIFFERENTIATION DISORDER; SIBLING;

AROMATASE; ARTHRITIS, RHEUMATOID; FAMILY HEALTH; FEMALE; GENETIC PREDISPOSITION TO DISEASE; HUMANS; INTRONS; LINKAGE (GENETICS); MALE; ODDS RATIO; PROBABILITY;

EID: 0033496361     PISSN: 00043591     EISSN: None     Source Type: Journal    
DOI: 10.1002/1529-0131(199908)42:8<1617::AID-ANR8>3.0.CO;2-N     Document Type: Article

References (17)

1. Rigby AS, Voelm L, Silman AJ. Epistatic modelling in rheumatoid arthritis: an application of the Risch theory. Genet Epidemiol 1993;10:311-20.
2. Silman AJ. Epidemiology of rheumatoid arthritis. In: Silman AJ, Hochberg M, editors. Epidemiology of rheumatic diseases. Oxford: Oxford University Press; 1993. p. 7-43.
3. Masi AT, Feigenbaum SL, Chatterton RT. Hormonal and pregnancy relationships to rheumatoid arthritis: convergent effects with immunological and microvascular systems. Scmin Arthritis Rheum 1995;25:1-27.
4. Wingrave SJ, Kay CR. Reduction in incidence of rheumatoid arthritis associated with oral contraceptives. Lancet 1978;1: 569-71.
5. Brennan P, Bankhead C, Silman A, Symmons D. Oral contraceptives and rheumatoid arthritis: results from a primary care-based incident case control study. Semin Arthritis Rheum 1997;26:817-23.
6. Wilder RL. Neuroendocrine-immune system interactions and autoimmunity. Annu Rev Immunol 1995;13:307-38.
7. Masi AT, Da Silva JAP, Cutulo M. Perturbations of hypothalamic-pituitary-gonadal (HPG) axis and adrenal androgen (AA) functions in rheumatoid arthritis. Baillieres Clin Rheumatol 1996;10: 295-332.
8. Worthington J, Ollier WER, Leach MK, Smith I, Hay EM, Thomson W, et al. The Arthritis and Rheumatism Council's National Repository of Family Material: pedigrees from the first 100 rheumatoid arthritis families containing affected sibling pairs. Br J Rheumatol 1994;33:970-6.
9. McGregor AJ, Bamber S, Silman AJ. A comparison of the performance of different methods of disease classification for rheumatoid arthritis: results and analysis from a nationwide twin study. J Rheumatol 1994;21:1420-6.
10. Polymeropoulos M, Xiao H, Rath D, Merril C. Tetranucleotide repeat polymorphism at the human aromatase cytochrome P-450 gene (CYP19). Nucleic Acids Res 1991;19:195.
11. Risch N. Linkage strategies for genetically complex traits. II. The power of affected relative pairs. Am J Hum Genet 1990; 46:229-41.
12. Holmans P. Asymptotic properties of affected sib-pair linkage analysis. Am J Hum Genet 1993;52:362-74.
13. Holmans P, Clayton D. Efficiency of typing unaffected relatives in an affected sib-pair linkage study with single-locus and multiple tightly linked markers Am J Hum Genet 1995;57:1221-32.
14. Symmons DP, Barret EM, Bankhead CR, Scott DG, Silman AJ. The incidence of rheumatoid arthritis in the United Kingdom: results from the Norfolk Arthritis Register. Br J Rheumatol 1994;33:735-9.
15. Wilder RL. Adrenal and gonadal steroid hormone deficiency in the etiopathogenesis of rheumatoid arthritis. J Rheumatol 1996;23 Suppl:1-12.
16. Watanabe J, Harada N, Suemasu K, Higashi Y, Gotoh O, Kawajiri K. Arginine-cysteine polymorphism at codon 264 of the human CYP19 gene does not affect aromatase activity. Pharmacogenetics 1997;7:419-24.
17. Risch N. Assessing the role of HLA-linked and unlinked determinants of disease. Am J Hum Genet 1987;40:1-14.