Maternal caffeine consumption during pregnancy does not affect preimplantation development but delays early postimplantation growth in rat embryos

Reproduction, Fertility and Development

Volumn 11, Issue 4-5, 1999, Pages 211-218

  Jacombs, Anita ^a   Ryan, John ^b   Loupis, Anne ^a   Pollard, Irina ^a  

^a MACQUARIE UNIVERSITY   (Australia)

^b N Shore Assisted Repro Technol   (Australia)

Author keywords

Embryogenesis; Implantation; Intrauterine growth retardation (IUGR); Neural tube closure; Toxicology

Indexed keywords

CAFFEINE;

ANIMAL EXPERIMENT; ARTICLE; BLASTOCYST; BRAIN DEVELOPMENT; CONTROLLED STUDY; INTRAUTERINE GROWTH RETARDATION; NEURAL TUBE; NIDATION; NONHUMAN; PREGNANCY; PREIMPLANTATION EMBRYO; PRENATAL EXPOSURE; RAT;

ANIMALS; BLASTOCYST; CAFFEINE; EMBRYONIC AND FETAL DEVELOPMENT; EMBRYONIC DEVELOPMENT; FEMALE; FETAL GROWTH RETARDATION; MATERNAL EXPOSURE; MICROSCOPY, ELECTRON, SCANNING; NEURAL TUBE DEFECTS; PREGNANCY; RATS; RATS, WISTAR;

EID: 0033495870     PISSN: 10313613     EISSN: None     Source Type: Journal    
DOI: 10.1071/rd99065     Document Type: Article

References (38)

1. Abdi, F., Pollard., I. and Wilkinson, J. (1993). Placental transfer and foetal disposition of caffeine and its immediate metabolites in the 20-day pregnant rat: function of dose. Xenobiotica 23, 449-56.
2. Behnke, M., and Eyler, F.D. (1993). The consequences of prenatal substance use for the developing fetus, newborn, and young child. Int. J. Addictions 28, 1341-91.
3. Berger, A. (1988). Effects of caffeine consumption on pregnancy outcome: a review. J. Reprod. Med. 33, 945-56.
4. Butcher, B.E.,Vorhes, C.V., and Wootten, V. (1984). Behavioural and physical development of rats chronically exposed to caffeinated fluids. Fundam. Appl. Toxicol. 4, 1-14
5. Collins, T.F.X., Welsh, J.J., Black, T.N., and Ruggles, D.L. (1983). A study of the teratogenic potential of caffeine ingested in drinking water. Food Chem. Toxicol. 21, 763-77.
6. Dlugosz L., and Bracken, M.B. (1992). Reproductive effects of caffeine: a review and theoretical analysis. Epidemiol. Rev. 14, 83-100.
7. Dunlop, M., and Court, J.M. (1981). Effects of maternal caffeine ingestation on neonatal growth in rats. Biol. Neonate 39, 178-84.
8. Fenster, L., Eskenazi, B., Windham, C., and Swan, S.H. (1992) Caffeine consumption during pregnancy and fetal growth. Am. J. Public Health 81, 458-61.
9. Fujii, T., and Nishimura, H. (1972). Adverse effects of prolonged administration of caffeine on rat fetus. Toxicol. Appl. Pharmacol. 22, 449-57.
10. Huges, R.N., and Beveridge, I.J. (1991). Behavioral effects of exposure to caffeine during gestation, lactation or both. Neurotoxicol. Teratol. 13, 641-7.
11. James, J.E. (1991). Caffeine and the methylxanthines. In 'Caffeine and Health', pp. 20-41. (Academic Press: San Diego, CA).
12. James, J.E., and Paull, I. (1985). Caffeine and human reproduction. Rev. Environ. Health 5, 151-67.
13. Knutti, R., Rothweiler, H., and Schlatter, C. (1982). Effect of pregnancy on the pharmacokinetics of caffeine. Arch. Toxicol. 5 (Suppl.), 187-92.
14. Legator, M.S., and Zimmering, S. (1979). Review of the genetic effects of caffeine. J. Environ. Sci. Health C13, 135-88.
15. Loupis, A., Ryan, J., Waite, K., and Pollard, I. (1996). Preconceptual caffeine exposure increases glucose utilization and accelerates development in the preimplantation rat embryo. J. Maternal-Fetal Med. 5, 321-7.
16. McDonald, A.D., Armstrong, B.G., and Sloan, M. (1992). Cigarette, alcohol, and coffee consumption and prematurity. Am. J. Public Health 82, 87-90.
17. Nakamoto, T., Hartman A.D., Miller, H.I., Temples T.E., and Quingy Jr, G.E. (1986). Chronic caffeine intake by rat dams during gestation and lactation affects various parts of the neonatal brain. Biol. Neonate 49, 227-83.
18. Narod S.A., de Sanjose, S., and Victora, C. (1991). Coffee during pregnancy: a reproductive hazard? Am. J. Obstet. Gynecol. 164, 1109-14.
19. Nolen, G.A. (1988). The developmental toxicology of caffeine. Issues Rev. Teratol. 4, 305-50.
20. O'Fallon, J.V. and Wright, R.W. (1986). Quantitative determination of the pentose phosphate pathway in preimplantation mouse embryos. Biol. Reprod. 34, 58-64.
21. Palm, P.E., Arnold E.P., Rachwall, P.C., Leyczek, L.C.,Teague, K.W, and Kensler, C.J. (1987). Evaluation of the teratogenic potential of fresh brewed coffee and caffeine in the rat. Toxicol. Appl. Pharmacol. 44, 1-16.
22. Pollard, I. (1988). Increases in plasma concentrations of steroids in the rat after the administration of caffeine : Comparison in plasma disposition of caffeine. J. Endocrinol. 119, 275-80.
23. Pollard, I. (1996). Preconceptual/prenatal care of our children: On the ethics of drug-induced disabilities. EUBIOS 6, 2-8.
24. Pollard, I., and Claassens, R. (1992). Caffeine-mediated effects on reproductive health over two generations in rats. Reprod. Toxicol. 6, 541-5.
25. Pollard, I., and Smallshaw, J. (1988). Male-mediated effects over two generations of rats. J. Dev. Physiol. 10, 271-81.
26. Pollard, I., Jabbour, H., and Mehrabani, P.A. (1987). Effects of caffeine administered during pregnancy on fetal development and subsequent function in the adult rat: prolonged effects on the second generation. J. Toxicol. Environ. Health 22, 1-15.
27. Pollard, I., Williamson, S., and Magre, S. (1990). Influence of caffeine administered during pregnancy on the early differentiation of fetal rat ovaries and testes. J. Dev. Physiol. 13, 59-65.
28. Quinn, P., Warnes., G.M., Kerin, J.F., and Kirby, C. (1985). Culture factors affecting the success rate of in vitro fertilization and embryo transfer. Ann. NY Acad. Sci. 442, 195-203.
29. Ryan, J.P., O'Neill, C., and Wales, R.G. (1990). Oxidative metabolism of energy substrates by preimplantation mouse embryos in the presence of platelet-activating factor. J. Reprod. Fertil. 89, 301-7.
30. Shigorska, B., and Bartel, H. (1970). Teratogenic effects of caffeine in white mice. Fol. Morph. 29, 353-63.
31. Sinton, C.M., Valatx, J.M., and Jouvet, M. (1981). Gestational caffeine modifies offspring behaviour in mice. Psychopharmacol. 75, 69-84.
32. Stanisstreet, M. (1990). Scanning electron microscopy and morphometry. In 'Postimplantation Mammalian Embryos. A Practical Approach'. (Eds A.J. Copp and D.L. Cockroft). pp. 109-26. (IRL Press: Oxford, UK).
33. Tye, K., Pollard, I., Karlsson, L., Scheibner, V., and Tye, G. (1993). Caffeine exposure in utero increases the incidence of apnea in adult rats. Reprod. Toxicol. 7, 449-52.
34. Watkinson, B., and Fried, P.A. (1985). Maternal caffeine use before, during and after pregnancy and effects upon offspring. Neurobehav. Toxicol. Teratol. 7, 9-17.
35. Wilcox, A., Weinber, C., and Baird, D. (1988). Caffeinated beverages and decreased fertility. Lancet 2, 1453-6.
36. Wilkinson, J.M., and Pollard, I. (1993). Accumulation of theophylline, theobromine and paraxanthine in the fetal rat brain following a single oral dose of caffeine. Dev. Brain Res. 75, 193-9.
37. Yazdani, M., Joseph Jr F., Grant, S., Hartman, A.D., and Nakamoto, T. (1990). Various levels of maternal caffeine ingestion during gestation affects biochemical parameters of fetal brain differently. Dev. Pharmacol. Ther. 14, 52-61.
38. York, R.G., Randall, J.L., and Scott Jr W.J. (1985). Reduction of caffeine teratogenicity in mice inducing maternal drug metabolism with β-naphthoflavone. Teratology 31, 217-25.