메뉴 건너뛰기




Volumn 23, Issue 7, 1999, Pages 489-495

D,L-α-difluoromethylornithine, an irreversible inhibitor of ornithine decarboxylase, induces differentiation in MEL cells

Author keywords

D,L difluoromethylornithine; Differentiation; Murine erythroleukemia cells

Indexed keywords

BROXURIDINE; DEXAMETHASONE; EFLORNITHINE; HEMOGLOBIN;

EID: 0033492924     PISSN: 10656995     EISSN: None     Source Type: Journal    
DOI: 10.1006/cbir.1999.0398     Document Type: Article
Times cited : (6)

References (48)
  • 1
    • 0018241978 scopus 로고
    • Induction of erythroid differentiation in Friend leukemia cells by bromodeoxyuridine
    • Adesnik M, Snitkin H. Induction of erythroid differentiation in Friend leukemia cells by bromodeoxyuridine. J Cell Physiol. 95:1978;307-318.
    • (1978) J Cell Physiol , vol.95 , pp. 307-318
    • Adesnik, M.1    Snitkin, H.2
  • 2
    • 0017228326 scopus 로고
    • Studies of cellular differentiation by automated cell separation. Two model systems: Friend virus-transformed cells andHydra attenuata
    • Arndt-Jovin DJ, Ostertag W, Eisen H, Klimek F, Jovin TM. Studies of cellular differentiation by automated cell separation. Two model systems: Friend virus-transformed cells andHydra attenuata. Cell. 24:1976;332-347.
    • (1976) Cell , vol.24 , pp. 332-347
    • Arndt-Jovin, D.J.1    Ostertag, W.2    Eisen, H.3    Klimek, F.4    Jovin, T.M.5
  • 3
    • 0026697676 scopus 로고
    • Increased survival of L1210 leukemic mice by prevention of the utilization of extracellular polyamines. Studies using a polyamine uptake mutant, antibiotics, and a polyamine-deficient diet
    • Ask A, Heby O. Increased survival of L1210 leukemic mice by prevention of the utilization of extracellular polyamines. Studies using a polyamine uptake mutant, antibiotics, and a polyamine-deficient diet. Cancer Lett. 66:1992;29-34.
    • (1992) Cancer Lett , vol.66 , pp. 29-34
    • Ask, A.1    Heby, O.2
  • 4
    • 0027278536 scopus 로고
    • Antileukemic effects of non-metabolizable derivatives of spermidine and spermine
    • Ask A, Persson L, Seiler N, Heby O. Antileukemic effects of non-metabolizable derivatives of spermidine and spermine. Cancer Lett. 69:1993;33-38.
    • (1993) Cancer Lett , vol.69 , pp. 33-38
    • Ask, A.1    Persson, L.2    Seiler, N.3    Heby, O.4
  • 6
    • 0027213483 scopus 로고
    • Interaction of a polyamine analogue 1,19-bis-(ethylamino)-5,10,15-triazanonadecane(BE4-4-4-4), with DNA and effect on growth, survival, and polyamine levels in seven human brain tumor cell lines
    • Basu HS, Pellarin M, Feuerstein BG, Shirahata A, Samejima K, Deen DF, Marton LJ. Interaction of a polyamine analogue 1,19-bis-(ethylamino)-5,10,15-triazanonadecane(BE4-4-4-4), with DNA and effect on growth, survival, and polyamine levels in seven human brain tumor cell lines. Cancer Res. 53:1993;3948-3955.
    • (1993) Cancer Res , vol.53 , pp. 3948-3955
    • Basu, H.S.1    Pellarin, M.2    Feuerstein, B.G.3    Shirahata, A.4    Samejima, K.5    Deen, D.F.6    Marton, L.J.7
  • 7
  • 8
    • 0024957745 scopus 로고
    • Polyamines and their derivatives as modulators in growth and differentiation
    • Canellakis ZE, Marsh LL, Bondy PK. Polyamines and their derivatives as modulators in growth and differentiation. The Yale J. Biol. Med. 62:1989;481-491.
    • (1989) The Yale J. Biol. Med. , vol.62 , pp. 481-491
    • Canellakis, Z.E.1    Marsh, L.L.2    Bondy, P.K.3
  • 9
    • 0020083989 scopus 로고
    • Changes of ornithine decarboxylase activity and polyamine content upon differentiation of mouse NB-15 neuroblastoma cells
    • Chen KY, Presepe V, Parken N, Liu AVC. Changes of ornithine decarboxylase activity and polyamine content upon differentiation of mouse NB-15 neuroblastoma cells. J Cell Physiol. 110:1982;285-290.
    • (1982) J Cell Physiol , vol.110 , pp. 285-290
    • Chen, K.Y.1    Presepe, V.2    Parken, N.3    Liu, A.V.C.4
  • 10
    • 0020025252 scopus 로고
    • Inducer-mediated commitment of murine erythroleukemia cells to differentiation: A multi-step process
    • Chen Z, Banks J, Rifkind RA, Marks PA. Inducer-mediated commitment of murine erythroleukemia cells to differentiation: a multi-step process. Proc Natl Acad Sci U S A. 79:1982;471-475.
    • (1982) Proc Natl Acad Sci U S a , vol.79 , pp. 471-475
    • Chen, Z.1    Banks, J.2    Rifkind, R.A.3    Marks, P.A.4
  • 13
    • 0016168103 scopus 로고
    • Induction of S-aminoleulinic acid synthetase during erythroid differentiation of cultured leukemia cells
    • Ebert P-S, Ikawa Y. Induction of S-aminoleulinic acid synthetase during erythroid differentiation of cultured leukemia cells. Proc Soc Exp Biol Med. 146:1974;601-604.
    • (1974) Proc Soc Exp Biol Med , vol.146 , pp. 601-604
    • Ebert, P.-S.1    Ikawa, Y.2
  • 14
    • 0015009308 scopus 로고
    • Haemoglobin synthesis in murine virus-induced leukemic cells in vitro: Stimulation of erythroid differentiation by dimethyl sulfoxide
    • Friend C, Scher W, Holland JG, Sato T. Haemoglobin synthesis in murine virus-induced leukemic cells in vitro: stimulation of erythroid differentiation by dimethyl sulfoxide. Proc Natl Acad Sci U S A. 68:1971;378-382.
    • (1971) Proc Natl Acad Sci U S a , vol.68 , pp. 378-382
    • Friend, C.1    Scher, W.2    Holland, J.G.3    Sato, T.4
  • 15
    • 0021073923 scopus 로고
    • Friend erythroleukemia cell differentiation: Induction by retinoids
    • Garg L-C, Brown J-C. Friend erythroleukemia cell differentiation: induction by retinoids. Differentiation. 25:1983;79-83.
    • (1983) Differentiation , vol.25 , pp. 79-83
    • Garg, L.-C.1    Brown, J.-C.2
  • 16
    • 0028920881 scopus 로고
    • Inhibition of cell growth by combination of α-difluoromethylornithine and an inhibitor of spermine synthase
    • He Y, Shimogori T, Kashiwagi D, Shirahata A, Igarashi K. Inhibition of cell growth by combination of α-difluoromethylornithine and an inhibitor of spermine synthase. J Biochem. 117:1995;824-829.
    • (1995) J Biochem , vol.117 , pp. 824-829
    • He, Y.1    Shimogori, T.2    Kashiwagi, D.3    Shirahata, A.4    Igarashi, K.5
  • 17
    • 0009560701 scopus 로고
    • Polyamine synthesis inhibitors act as both inducers and suppressors of cell differentiation
    • P.P. McCann, A.E. Pegg, & A. Sjoerdsma. Orlando: Academic Press
    • Heby O, Luk GD, Schindler J. Polyamine synthesis inhibitors act as both inducers and suppressors of cell differentiation. McCann PP, Pegg AE, Sjoerdsma A. Inhibition of polyamine metabolism. Biological significance and basis for new therapies. 1987;165-186 Academic Press, Orlando.
    • (1987) Inhibition of Polyamine Metabolism. Biological Significance and Basis for New Therapies , pp. 165-186
    • Heby, O.1    Luk, G.D.2    Schindler, J.3
  • 18
    • 0027202387 scopus 로고
    • Polyamines are essential for cell transformation by pp60v0src: Delineation of molecular events for the transformed phenotype
    • Holtta E, Auvine M, Andersson L-C. Polyamines are essential for cell transformation by pp60v0src: Delineation of molecular events for the transformed phenotype. J Cell Biol. 122:1993;903-909.
    • (1993) J Cell Biol , vol.122 , pp. 903-909
    • Holtta, E.1    Auvine, M.2    Andersson, L.-C.3
  • 19
    • 0027077604 scopus 로고
    • Chemoprevention in prostate cancer: The role of difluoromethyl ornithine (DFMO)
    • Kadmon D. Chemoprevention in prostate cancer: the role of difluoromethyl ornithine (DFMO). J Cell Biochem Suppl. 16:1992;122-127.
    • (1992) J Cell Biochem Suppl , vol.16 , pp. 122-127
    • Kadmon, D.1
  • 20
    • 0018557674 scopus 로고
    • Alterations in translational control mechanisms in Friend erythroleukemic cells during dimethylsulfoxide induced differentiation
    • Koch G, Weber C, Bilelleo JA. Alterations in translational control mechanisms in Friend erythroleukemic cells during dimethylsulfoxide induced differentiation. Hematol Bluttransfus. 23:1979;295-301.
    • (1979) Hematol Bluttransfus , vol.23 , pp. 295-301
    • Koch, G.1    Weber, C.2    Bilelleo, J.A.3
  • 21
    • 0018582953 scopus 로고
    • Memory of MEL cells to a previous exposure to inducer
    • Levenson R, Housman D. Memory of MEL cells to a previous exposure to inducer. Cell. 17:1979;485-490.
    • (1979) Cell , vol.17 , pp. 485-490
    • Levenson, R.1    Housman, D.2
  • 22
    • 0027058343 scopus 로고
    • A prospective clinical trial of difluoromethyl ornithine (DFMO) in patients with resected superficial bladder cancer
    • Loprinzi CL, Messing FM. A prospective clinical trial of difluoromethyl ornithine (DFMO) in patients with resected superficial bladder cancer. J Cell Biochem Suppl. 161:1992;153-155.
    • (1992) J Cell Biochem Suppl , vol.161 , pp. 153-155
    • Loprinzi, C.L.1    Messing, F.M.2
  • 23
    • 0001092512 scopus 로고
    • Regulation of normal differentiation in mouse and human myeloid leukemia cells by phorbol esters and the mechanism of tumor promotion
    • Lotem J, Sachs J. Regulation of normal differentiation in mouse and human myeloid leukemia cells by phorbol esters and the mechanism of tumor promotion. Proc Natl Acad Sci U S A. 76:1979;5158-5162.
    • (1979) Proc Natl Acad Sci U S a , vol.76 , pp. 5158-5162
    • Lotem, J.1    Sachs, J.2
  • 24
    • 0018257047 scopus 로고
    • Early transport changes during erythroid differentiation of Friend leukemic cells
    • Mager D, Bernstein A. Early transport changes during erythroid differentiation of Friend leukemic cells. J Cell Physiol. 94:1978;275-286.
    • (1978) J Cell Physiol , vol.94 , pp. 275-286
    • Mager, D.1    Bernstein, A.2
  • 25
  • 26
    • 0029134770 scopus 로고
    • Development of difluoromethyl ornithine as a chemoprevention agent for the management of colon cancer
    • Meyskens FL Jr, Gerner EW. Development of difluoromethyl ornithine as a chemoprevention agent for the management of colon cancer. J Cell Biochem Suppl. 22:1995;126-131.
    • (1995) J Cell Biochem Suppl , vol.22 , pp. 126-131
    • Meyskens F.L., Jr.1    Gerner, E.W.2
  • 28
    • 0028215197 scopus 로고
    • Effects on tumor induction, growth, metastasis and histology of concurrent administration of putrescine and its metabolizing inhibitor α-difluoromethylornithine in nickel tumorigenesis in soft tissue
    • Ohmori T, Okada K, Tabei R, Shibata T. Effects on tumor induction, growth, metastasis and histology of concurrent administration of putrescine and its metabolizing inhibitor α-difluoromethylornithine in nickel tumorigenesis in soft tissue. Carcinogenesis. 15:1994;647-652.
    • (1994) Carcinogenesis , vol.15 , pp. 647-652
    • Ohmori, T.1    Okada, K.2    Tabei, R.3    Shibata, T.4
  • 29
    • 0343596536 scopus 로고
    • Differentiation in erythroleukemic cells and their somatic hybrids
    • Orkin SH, Harosi FI, Leder P. Differentiation in erythroleukemic cells and their somatic hybrids. Proc Natl Acad Sci U S A. 72:1975;98-102.
    • (1975) Proc Natl Acad Sci U S a , vol.72 , pp. 98-102
    • Orkin, S.H.1    Harosi, F.I.2    Leder, P.3
  • 30
    • 0023881236 scopus 로고
    • Polyamine metabolism and its importance in neoplastic growth and as a target for chemotherapy
    • Pegg AE. Polyamine metabolism and its importance in neoplastic growth and as a target for chemotherapy. Cancer Res. 48:1988;744-759.
    • (1988) Cancer Res , vol.48 , pp. 744-759
    • Pegg, A.E.1
  • 31
    • 0029455991 scopus 로고
    • Ornithine decarboxylase as a target for chemoprevention
    • Pegg AE, Shantz LM, Coleman CS. Ornithine decarboxylase as a target for chemoprevention. J Cell Biochem Suppl. 22:1995;132-138.
    • (1995) J Cell Biochem Suppl , vol.22 , pp. 132-138
    • Pegg, A.E.1    Shantz, L.M.2    Coleman, C.S.3
  • 32
    • 0029455991 scopus 로고
    • Ornithine decarboxylase as a target for chemoprevention
    • Pegg AE, Shantz LM, Coleman CS. Ornithine decarboxylase as a target for chemoprevention. J Cell Biochem Suppl. 22:1995;132-138.
    • (1995) J Cell Biochem Suppl , vol.22 , pp. 132-138
    • Pegg, A.E.1    Shantz, L.M.2    Coleman, C.S.3
  • 33
    • 0028880977 scopus 로고
    • Relationship between ornithine decarboxylase cytoskeletal organization in cultured human keratinocytes: Cellular responses to phorbol esters, cytochalasins and alph difluoromethylornithine
    • Pomidor MM, Ruhl KK, Zheng P, Song Y, Joanne OA, Tuan RS, Hickok NJ. Relationship between ornithine decarboxylase cytoskeletal organization in cultured human keratinocytes: cellular responses to phorbol esters, cytochalasins and alph difluoromethylornithine. Exp Cell Res. 221:1995;426-437.
    • (1995) Exp Cell Res , vol.221 , pp. 426-437
    • Pomidor, M.M.1    Ruhl, K.K.2    Zheng, P.3    Song, Y.4    Joanne, O.A.5    Tuan, R.S.6    Hickok, N.J.7
  • 34
    • 0029584282 scopus 로고
    • 12-bis(ethyl)spermine in L1210 leukaemia cells
    • 12-bis(ethyl)spermine in L1210 leukaemia cells. Biochem J. 312:1995;749-756.
    • (1995) Biochem J , vol.312 , pp. 749-756
    • Poulin, R.1    Pegg, A.E.2
  • 35
    • 0029023317 scopus 로고
    • Induction of differentiation in murine erythroleukemia cells by 1α, 25-dihydroxy vitamin D3
    • Radhika S, Choudhary SK, Garg LC, Dixit A. Induction of differentiation in murine erythroleukemia cells by 1α, 25-dihydroxy vitamin D3. Cancer Lett. 90:1995;225-230.
    • (1995) Cancer Lett , vol.90 , pp. 225-230
    • Radhika, S.1    Choudhary, S.K.2    Garg, L.C.3    Dixit, A.4
  • 36
    • 0018147505 scopus 로고
    • Changes in ornithine decarboxylase activity during matrix-induced cartilage, bone and bone marrow differentiation
    • Rath NC, Reddi AH. Changes in ornithine decarboxylase activity during matrix-induced cartilage, bone and bone marrow differentiation. Biochem Biophys Res Commun. 81:1978;106-113.
    • (1978) Biochem Biophys Res Commun , vol.81 , pp. 106-113
    • Rath, N.C.1    Reddi, A.H.2
  • 37
    • 0015466148 scopus 로고
    • Globin messenger RNA induction during erythroid differentiation of cultured leukemia cells
    • Ross J, Ikawa Y, Leder P. Globin messenger RNA induction during erythroid differentiation of cultured leukemia cells. Proc Natl Acad Sci U S A. 79:1972;3620-3623.
    • (1972) Proc Natl Acad Sci U S a , vol.79 , pp. 3620-3623
    • Ross, J.1    Ikawa, Y.2    Leder, P.3
  • 38
    • 0017404231 scopus 로고
    • Tumour promoters inhibit spontaneous differentiation of Friend erythroleukemia cells in culture
    • Rovera G, O'Brien T, Diamond L. Tumour promoters inhibit spontaneous differentiation of Friend erythroleukemia cells in culture. Proc Natl Acad Sci U S A. 74:1977;2894-2896.
    • (1977) Proc Natl Acad Sci U S a , vol.74 , pp. 2894-2896
    • Rovera, G.1    O'Brien, T.2    Diamond, L.3
  • 39
    • 0018148864 scopus 로고
    • Control of normal cell differentiation and the phenotypic reversion of malignancy in meyloid leukemia
    • Sachs L. Control of normal cell differentiation and the phenotypic reversion of malignancy in meyloid leukemia. Nature. 284:1978;535-539.
    • (1978) Nature , vol.284 , pp. 535-539
    • Sachs, L.1
  • 40
    • 0026559923 scopus 로고
    • Polyamine deprivation, malnutrition and tumor growth
    • Sarhan S, Bolkenius FN, Rennert OM. Polyamine deprivation, malnutrition and tumor growth. Anticancer Res. 12:1992;457-466.
    • (1992) Anticancer Res , vol.12 , pp. 457-466
    • Sarhan, S.1    Bolkenius, F.N.2    Rennert, O.M.3
  • 41
    • 0017289492 scopus 로고
    • Sequential induction of enzymes of the heme biosynthetic pathway in Friend erythroleukemia cells in culture
    • Sassa S. Sequential induction of enzymes of the heme biosynthetic pathway in Friend erythroleukemia cells in culture. J Exp Med. 143:1976;305-315.
    • (1976) J Exp Med , vol.143 , pp. 305-315
    • Sassa, S.1
  • 42
    • 0020966292 scopus 로고
    • Inhibition of ornithine decarboxylase induces embryonal carcinoma cell differentiation
    • Schindler J, Kelly M, McCann PP. Inhibition of ornithine decarboxylase induces embryonal carcinoma cell differentiation. Biochem Biophys Res Commun. 114:1983;410-417.
    • (1983) Biochem Biophys Res Commun , vol.114 , pp. 410-417
    • Schindler, J.1    Kelly, M.2    McCann, P.P.3
  • 43
    • 0025298549 scopus 로고
    • Polyamine transport in mammalian cells
    • Seiler N, Dezeure F. Polyamine transport in mammalian cells. Int J Biochem. 22:1990;211-218.
    • (1990) Int J Biochem , vol.22 , pp. 211-218
    • Seiler, N.1    Dezeure, F.2
  • 44
    • 0021267038 scopus 로고
    • Effects of polyamine depletion on proliferation and differentiation of murine erythroleukemia cells
    • Sugiura M, Shafman T, Kafe D. Effects of polyamine depletion on proliferation and differentiation of murine erythroleukemia cells. Cancer Res. 44:1984;1440-1444.
    • (1984) Cancer Res , vol.44 , pp. 1440-1444
    • Sugiura, M.1    Shafman, T.2    Kafe, D.3
  • 45
    • 0019499636 scopus 로고
    • Effects of parathyroid hormones and cyclic AMP analogues on the activity of ornithine decarboxylase and expression of the differentiated phenotype of chondrocytes in culture
    • Takigawa M, Takano T, Suzuki F. Effects of parathyroid hormones and cyclic AMP analogues on the activity of ornithine decarboxylase and expression of the differentiated phenotype of chondrocytes in culture. J Cell Physiol. 106:1981;259-268.
    • (1981) J Cell Physiol , vol.106 , pp. 259-268
    • Takigawa, M.1    Takano, T.2    Suzuki, F.3
  • 46
    • 0028059218 scopus 로고
    • Characterization of polyamine transport in rat aortic smooth muscle cells
    • Toursarkissian B, Endean ED, Aziz SM. Characterization of polyamine transport in rat aortic smooth muscle cells. J Surg Res. 57:1994;401-407.
    • (1994) J Surg Res , vol.57 , pp. 401-407
    • Toursarkissian, B.1    Endean, E.D.2    Aziz, S.M.3
  • 47
    • 0022889285 scopus 로고
    • Effects of ornithine decarboxylase inhibition on c-myc expression during murine erythroleukemia cell proliferation and differentiation
    • Watanabe T, Sherman M, Shafman T, Iwata T, Kufe D. Effects of ornithine decarboxylase inhibition on c-myc expression during murine erythroleukemia cell proliferation and differentiation. J Cell Physiol. 127:1986;480-484.
    • (1986) J Cell Physiol , vol.127 , pp. 480-484
    • Watanabe, T.1    Sherman, M.2    Shafman, T.3    Iwata, T.4    Kufe, D.5
  • 48
    • 0019425999 scopus 로고
    • Erythroid differentiation and commitment in rat erythroleukemia cells with hypertonic culture conditions
    • Yamaguchi Y, Kluuge N, Ostertag W, Furusawa M. Erythroid differentiation and commitment in rat erythroleukemia cells with hypertonic culture conditions. Proc Natl Acad Sci U S A. 78:1981;2325-2329.
    • (1981) Proc Natl Acad Sci U S a , vol.78 , pp. 2325-2329
    • Yamaguchi, Y.1    Kluuge, N.2    Ostertag, W.3    Furusawa, M.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.