Enhanced production of penicillin V acylase from Streptomyces lavendulae

Applied Microbiology and Biotechnology

Volumn 53, Issue 1, 1999, Pages 81-84

  Torres, R ^a   Ramon F ^a   De La Mata, I ^a   Acebal, C ^a   Castillon M P ^a  

^a UNIVERSIDAD COMPLUTENSE DE MADRID   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

AMIDASE; BACTERIAL ENZYME; PENICILLIN V;

ARTICLE; BACTERIUM CULTURE; ENZYME ACTIVITY; ENZYME STABILITY; ENZYME SYNTHESIS; NONHUMAN; PH; STREPTOMYCES LAVENDULAE;

ACTINOBACTERIA (CLASS); BACTERIA (MICROORGANISMS); STREPTOMYCES LAVENDULAE; UNCULTURED ACTINOMYCETE;

EID: 0033491935     PISSN: 01757598     EISSN: None     Source Type: Journal    
DOI: 10.1007/s002530051618     Document Type: Article

References (21)

1. Balasingham K, Warburton D, Dunnill P, Lilly D (1972) The isolation and kinetics of penicillin amidase from Escherichia coli. Biochim Biophys Acta 270: 250-256
2. Bradford MH (1976) A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 72: 248-274
3. Carlsen F, Emborg C (1982) Bacillus sphaericus penicillin acylase. I. Isolation and characterization. J Chem Technol Biotechnol 32: 808-811
4. Cooney CL (1981) Growth of microorganisms. In: Rehm HJ, Reed G (eds) Biotechnology, vol 1.VCH, Weinheim, pp 92-93
5. Desphande BS, Ambedkar SS, Sudhakaran VK, Shewale JG (1994) Molecular biology of β-lactam acylases. World J Microbiol Biotechnol 10: 129-138
6. Desphande BS, Ambedkar SS, Shewale JG (1996) Cephalosporin C acylase and penicillin V acylase formation by Aeromonas sp. ACY95. World J Microbiol Biotechnol 12: 373-378
7. García-Ochoa F, Santos VE, Alcón A (1998) Intracellular compound quantification by means of flow cytometry in bacteria. Biotechnol Bioeng 57: 87-94
8. Hamilton-Miller JMT (1966) Penicillin acylase. Bacteriol Rev 30: 761-771
9. Huber FM, Chauvette RR, Jackson BG (1972) Preparative methods for 7-aminocephalosporanic acid and 6-aminopenicillanic acid. In: Flynn EH(ed) Cephalosporins and penicillin compounds: their chemistry and biology. Academic Press, New York, pp 27-73
10. Lowe DA, Romanicik KG, Blander RP (1981) Penicillin acylases: a review of existing enzymes and the isolation of a new bacterial penicillin V acylase. Dev Ind Microbiol 22: 163-180
11. Mahajan PB (1984) Penicillin acylases: an update. Applied Biochem Biotechnol 9: 537-554
12. Pundle A, SivaRaman H (1997) Bacillus sphaericus penicillin V acylase: purification, substrate specificity and active site characterization. Curr Microbiol 34: 144-148
13. Rolinson GN, Batchelor FR, Butterworth D, Wood JC, Cole M, Eustace GC, Harst MV, Richards M, Chain EB (1960) Formation of 6-aminopenicillanic acid from penicillin by enzyme hydrolysis. Nature 187: 236-237
14. Rolinson GN, Richards M, Batchelor FR (1961) Production of 6-aminopenicillanic acid. US patent application 3014845, 3014846, 26 December
15. Schneider WJ, Roehr M (1976) Purification and properties of penicillin V acylase of Bovista plumbea. Biochim Biophys Acta 452: 177-181
16. Shewale JG, SivaRaman H (1989) Penicillin acylases: enzyme production and its application in the manufacture of 6-APA. Process Biochem 24: 146-154
17. Shewale JG, Sudhakaran VK (1997) Penicillin V acylase: its potential in the production of 6-aminopenicillanic acid. Enzyme Microbiol Technol 20: 402-410
18. Shewale JG, Desphande BS, Sudhakaran UK, Ambedkar SS (1990) Penicillin acylases: applications and potentials. Process Biochem 25: 97-103
19. Sudhakaran VK, Shewale JG (1995) Purification and characterization of extracellular penicillin V acylase from Fusarium sp. Hind Antibiot Bull 37: 9-15
20. Torres R, Mata I, Castillón MP, Arroyo M, Torres J, Acebal C (1998) Purification and characterization of penicillin V acylase from Streptomyces lavendulae. In: Ballesteros A, Plou FJ, Iborra JL, Hailing PJ (eds) Progress in biotechnology 15. Stability and stabilization of biocatalysts. Elsevier, Amsterdam, pp 719-724
21. Vandamme EJ (1980) Penicillin acylases and β-lactamases. In: Rose AH (ed) Economic microbiology, vol 5. Academic Press, New York, pp 467-479