Evidences for adduct formation between intracellular non-protein thiols and nitroazoles possessing an α,β-unsaturated carbonyl side chain and the effects on radiosensitization of hypoxic cells

Bioorganic and Medicinal Chemistry

Volumn 7, Issue 11, 1999, Pages 2591-2598

  Zhou, Ling ^a   Ino, Akira ^a   Dai, Wei Min ^b   Nishimoto, Sei Ichi ^a  

^a KYOTO UNIVERSITY   (Japan)

^b HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Hong Kong)

Author keywords

Hypoxic cell; Nitroazoles; NPSH depletion; Radiosensitization

Indexed keywords

CYSTEINE; DNA; GLUTATHIONE; PYRROLE DERIVATIVE; THIOL DERIVATIVE;

ARTICLE; CELL CULTURE; DOSE RESPONSE; HYPOXIA; RADIATION DOSE; RADIOSENSITIZATION; X IRRADIATION;

AZOLES; BUFFERS; CELL HYPOXIA; CELLS, CULTURED; CYSTEINE; DOSE-RESPONSE RELATIONSHIP, RADIATION; GLUTATHIONE; HUMANS; PHOSPHATES; RADIATION TOLERANCE; SULFHYDRYL COMPOUNDS;

EID: 0033491806     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0968-0896(99)00187-X     Document Type: Article

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