Cellulose and calcium lower the incidence of chemically-induced colon tumors in rats

Plant Foods for Human Nutrition

Volumn 54, Issue 4, 1999, Pages 295-303

  Ranhotra, G S ^a   Gelroth, J A ^a   Glaser, B K ^a   Schoening, P ^b   Brown, S E ^b  

^a American Institute of Baking   (United States)

^b KANSAS STATE UNIVERSITY   (United States)

Author keywords

Calcium; Cellulose; Colon tumors; Folic acid

Indexed keywords

ANTINEOPLASTIC AGENT; CARCINOGEN; CELLULOSE; DIMETHYLHYDRAZINE; FOLIC ACID;

ADENOCARCINOMA; ADENOMA; ANIMAL; ARTICLE; CALCIUM INTAKE; COLON TUMOR; DIETARY FIBER; DISEASE MODEL; FISCHER 344 RAT; MALE; RANDOMIZATION; RAT;

ADENOCARCINOMA; ADENOMA; ANIMALS; ANTICARCINOGENIC AGENTS; CALCIUM, DIETARY; CARCINOGENS; CELLULOSE; COLONIC NEOPLASMS; DIETARY FIBER; DIMETHYLHYDRAZINES; DISEASE MODELS, ANIMAL; FOLIC ACID; MALE; RANDOM ALLOCATION; RATS; RATS, INBRED F344;

ANIMALIA;

EID: 0033491703     PISSN: 09219668     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1008149107282     Document Type: Article

References (26)

1. Silverberg F, Lubera JA (1989) Cancer statistics. Cancer 39: 3.
2. ACS (1991) Cancer facts and figures, 1991. New York: American Cancer Society.
3. Potter JD, McMichael AJ (1986) Diet and cancer of the colon and rectum: A case-control study. J Natl Cancer Inst 76: 557.
4. Slavin JL (1990) Dietary fiber: Mechanisms or magic on disease prevention. Nutr Today 25 (6): 6.
5. Ausman LM (1993) Fiber and colon cancer: Does the current evidence justify a preventive policy. Nutr Rev 51: 57.
6. Dwyer J (1993) Dietary fiber and colorectal cancer risk. Nutr Rev 51: 147.
7. Karkare MR, Clark TD, Glauert HP (1991) Effect of dietary calcium on colon carcinogenesis induced by a single injection of 1,2-dimethylhydrazine in rats. J Nutr 121: 568.
8. Sitrin MD, Halline AG, Abrahms C, Brasitus TA (1991) Dietary calcium and vitamin D modulate 1,2-dimethylhydrazine-induced colonic carcinogenesis in the rat. Cancer Res 51: 5608.
9. Lupton JR, Steinbach G, Chang WC, O'Brien BC, Wiese S, Stoltzfus CL, Glober GA, Wargovitch MJ, McPherson RS, Winn RJ (1996) Calcium supplementation modifies the relative amounts of bile acids in bile and affects key aspects of human colon physiology. J Nutr 126: 1421.
10. Cravo ML, Mason JB, Dayal Y, Hutchinson M, Smith D, Selhub J, Rosenberg IH (1992) Folate deficiency enhances the development of colonic neoplasia in dimethylhydrazine-treated rats. Cancer Res 52: 5002.
11. Mason JB (1994) Folate and colonic carcinogenesis: Searching for a mechanistic understanding. J Nutr Biochem 5: 170.
12. McSherry CK, Cohen BI, Bokkenhauser VD, Mosbach EH, Winter J, Matoba, N, Scholes J (1989) Effects of calcium and bile acid feeding on colon tumors in the rats. Cancer Res 49: 6039.
13. Lashner BA, Heidenreich PA, Su GL, Kane SK, Hanauer SB (1989) Effect of folate supplementation on the incidence of dysplasia and cancer in chronic ulcerative colitis. Gastroent 97: 255.
14. Baggott JE, Vaughn WH, Juliana MM, Eto I, Krumdieck L, Grubbs CJ (1992) Effects of folate deficiency and supplementation on methylnitrosourea-induced rat mammory tumors. J National Cancer Res 84: 1740.
15. Reddy BS, Sugie S (1988) Effect of different levels of omega-3 and omega-6 fatty acids on azoxymethane-induced colon carcinogenesis in F344 rats. Cancer Res 48: 6642.
16. Clinton SK, Imrey PB, Mangian HJ, Nandkumar S, Visek WJ (1992) The combined effects of dietary fat, protein, and energy intake on azoxymethane-induced intestinal and renal carcinogenesis. Cancer Res 52: 857.
17. Maziya-Dixon BB, Klopfenstein CF, Leipold HW (1994) Protective effects of hard red versus hard white winter wheats in chemically induced colon cancer in CF1 mice. Cereal Chem 71: 359.
18. Dillehay DL, Webb SK, Schmelz EM, Merril JR AH (1994) Dietary sphingomyelin inhibits 1,2-dimethylhydrazine-induced colon cancer in CF1 mice. Nutr 124: 615.
19. Madara J, Harte P, Deasy J, Ross R, Lahey S, Steele A (1983) Evidence for an adenoma-carcinoma sequence in dimethylhydrazine-induced neoplasms of rat intestinal epithelium. Am J Pathol 110: 230.
20. Wilson RB, Hutcheson DP, Wideman L (1977) Dimethylhydrazine-induced colon tumors in rats fed diets containing beef fat or corn oil with and without wheat bran. Am J Clin Nutr 30: 176.
21. Kuratko C, Pence BC (1992) Rat colonic antioxidant status: Interaction of dietary fats with 1,2-dimethylhydrazine challenge. J Nutr 122: 278.
22. NRC (1987) Nutrient requirements of laboratory animals. In Nutrient Requirements of Domesticated Animals. Washington, DC: National Academy of Sciences/National Research Council.
23. SAS (1982) SAS User's Guide. Cary, NC: The Institute.
24. Caderni G, Luceri C, Spagnesi MT, Giannini A, Biggeri A, Dolara P (1994) Dietary carbohydrates modify azoxymethane-induced intestinal carcinogenesis in rats. J Nutr 124: 517.
25. Freeman HJ, Spiler GA, Kim YS (1980) A double-blind study on the effects of differing purified cellulose and pectin fiber diets on 1,2-dimethylhydrazine-induced rat colonic neoplasia. Cancer Res 4: 2661.
26. Reddy BS, Mori H (1981) Effect of dietary wheat bran and dehydrated citrus fiber on 3,2-dimethyl-4-aminobiphenyl-induced intestinal carcinogenesis in F344 rats. Carcinogenesis 2: 21.